sock_o

Work hard, play harder ️ ️ ️

[Massimo @Rainmaker1973]

Psilocybin made human cells live 50% longer.

A new study has uncovered surprising anti-aging potential in psilocin—the active metabolite produced when the body breaks down psilocybin, the psychoactive compound found in magic mushrooms.

In laboratory experiments, researchers exposed two human cell lines (skin fibroblasts and fetal lung fibroblasts) to a 100 μM concentration of psilocin. The results were striking: lung cells took 57% longer to reach replicative senescence (the point at which cells permanently stop dividing and accumulate damage), while skin fibroblasts extended their replicative lifespan by 51%.

These findings suggest psilocin may slow fundamental cellular aging processes, possibly by lowering oxidative stress, enhancing DNA-repair pathways, supporting mitochondrial health, or dampening chronic inflammation—mechanisms that overlap with those targeted by leading experimental longevity drugs.

The benefits extended beyond cell culture. In aged female mice (19 months old at the start, equivalent to approximately 60–65 human years), a single monthly dose of psilocybin dramatically improved outcomes. After 10 months of treatment, 80% of the psilocybin-treated animals remained alive, compared with only 50% of untreated controls. Treated mice also displayed markedly fewer visible signs of aging, including reduced fur loss and graying.

This research marks the first direct demonstration that psilocybin/psilocin can influence biological aging itself, rather than solely producing psychological effects. The authors emphasize that the study used relatively conservative dosing and are now advocating for follow-up work with higher or more frequent administration, detailed assessments of immune, metabolic, and cognitive function, and investigations into whether the extended lifespan corresponds to genuine improvements in healthspan and quality of life.

["Psilocybin treatment extends cellular lifespan and improves survival of aged mice." npj Aging, 2025]

[Rob Dyrdek @robdyrdek]

In 2015 I built a spreadsheet that would change my perspective on time forever. I realized time had a clear structure and everything unfolded in this structure. This Rhythm of Existence capacity planner is the genesis of what https://t.co/9yB9qxQNBf would become 10 years later.

[Dr. Nicole LePera @Theholisticpsyc]

Is ADHD actually complex trauma in some people?

My answer to this question:

[sock_o @sock_o]

@tomgreenlive Yup 🫡

[Dr. Rhonda Patrick @foundmyfitness]

Two cannabis compounds commonly found in hemp were able to bind to the spike protein and prevent the SARS-CoV2 virus from entering cells and causing infection.

The authors suggest that since hemp is safe it should be explored as a potential therapeutic.

https://t.co/DIOfWqPRUe

[sock_o @sock_o]

Merry Christmas 🎄🎁🎅🏽

Joe Rogan - Santa Claus Was a Mushroom! https://t.co/glERXYbpdY via @YouTube

[sock_o @sock_o]

@TheDailyShroom Trauma

[sock_o @sock_o]

@CHEK_News No.

[Kate Quigley @KateQFunny]

😂 😂 😂 Hilarious @TinFoilHatCast

[Lori Shemek, PhD @LoriShemek]

This 30-Year Harvard Study Reveals 5 Daily Habits Can Add 12 to 14 Years to Your Life (and Cut Your Risk of Alzheimer's in Half)
#health #longevity #brainhealth https://t.co/PgTmg83zAs

[Edward Snowden @Snowden]

Apple and Google intend to push pandemic trackers into most of the world's smartphones. In response, @ACLU just published a whitepaper listing bottom-line principles phone-based contact-tracing systems must follow to comply with basic rights. Summary: https://t.co/ZZ4KuaKUIb

[sock_o @sock_o]

@hartluck White rum and coconut water

[Marc Emery @MarcScottEmery]

We aren’t “in this together”. Old people have homes paid off, pensions, assets, investments, savings & children grown up.Young people have debt,live paycheque to paycheque, pay rent,have young children,have no investments or savings & will pay suffocating taxes for crisis forever

[Lori Shemek, PhD @LoriShemek]

Protein is one of the building blocks of antibodies, which are produced by the body’s immune system to help fight off foreign invaders like bacteria and viruses.

Keep your protein intake up to strengthen immunity.

#immunity #protein #antibodies #saturdaymotivation

[Insider Tech @TechInsider]

This is what having the novel coronavirus looks like

[Graham Hancock @Graham__Hancock]

Celebrating the marriage of heaven and earth. Left: the alignment of the rising equinox sun with the central tower of Angkor Wat. Right: rear view of the head of the Great Sphinx silhouetted at dawn. It's gaze directly targets the rising equinox sun.
Photos: Santha Faiia

[Twisted🀄trucker @twisted_trucker]

Anybody looking for stock tips..
No hockey. No basketball. No March madness. No soccer. We're all quarantined. What else is left?..

I'm putting it all in Pampers.
It's gonna pay off huge in 9 months.

[Mashable @mashable]

This artificial human cornea only takes 10 minutes to 3D print https://t.co/PObGWbGT1R