Scientists have identified specific gut bacteria that appear to trigger multiple sclerosis (MS).
In a groundbreaking study conducted at Ludwig Maximilian University of Munich, researchers examined 81 pairs of identical twins in which only one sibling had MS. This unique design allowed them to control for genetic and environmental factors, isolating the role of the microbiome.
The team found that two bacterial species, Eisenbergiella tayi and Lachnoclostridium, were significantly more abundant in the twins with MS. When these microbes were transferred into mouse models, they directly induced MS-like autoimmune symptoms, providing strong causal evidence.
This is the most precise identification of microbial triggers for MS to date and adds powerful support to the gut-brain axis in autoimmune disease. The discovery raises hope for new approaches to early detection, prevention, and treatment — potentially by targeting or modulating these specific bacteria before symptoms appear.
While human clinical trials are still needed, the findings represent a major step toward microbiome-based therapies for MS and other autoimmune conditions.
[Yoon, H., Gerdes, L. A., Beigel, F., Sun, Y., Kövilein, J., Wang, J., Kuhlmann, T., Flierl-Hecht, A., Haller, D., Hohlfeld, R., Baranzini, S. E., Wekerle, H., & Peters, A. (2025). Multiple sclerosis and gut microbiota: Lachnospiraceae from the ileum of MS twins trigger MS-like disease in germfree transgenic mice—An unbiased functional study. Proceedings of the National Academy of Sciences, 122(18), e2419689122. DOI: 10.1073/pnas.2419689122]
#RolandGarros is a joke of a grand slam not having Hawkeye - #CasperRuud won that second set. Every other major is capable of electronic line review but no the French must be stubborn fools
It is with profound sadness that we announce the unexpected passing of Nathan Allman, Ondo's founder. Our hearts are with his family and loved ones.
Nate’s brilliance, humility, and drive shaped every part of what Ondo is today. His belief in the power of technology to create a more open, accessible financial system lives on in everything we build. The impact he had on this industry, and on all of us personally, cannot be overstated.
Nate also helped us build a durable organization with experienced leaders across all facets of the business. Ian De Bode, Ondo Finance’s longtime President, will serve as CEO. Ian has been leading our strategy, product, and day-to-day operations for over two years and has the full confidence of the leadership team.
We will continue building what Nate started. That is the most meaningful way we know to honor him.
ArcNova has raised $15M to power the infrastructure behind AI-native entertainment.
Thanks to our strategic investors and partners:
@Adaverse_Acc@animocabrands@Liquid_Capital_@Redline_Labs@waterdripfund
The future of storytelling is shifting from studios to systems.
Create. Watch. Earn.
RFK Jr: "A Democratic senator claimed it's mathematically impossible to have a drug drop by 600%. I said, 'Well, if the drug was $100 and it raises to $600, that would be a 600% rise. If it drops from $600 to $100, that's a 600% savings.'"
Trump: "Right"
Introducing Predicate Asset Compliance: Automated compliance controls for stablecoins and RWAs.
Issuers define policies for who can and can’t access their assets. Predicate enforces them in real time, directly onchain.
Here's how it works and why we built it.
TUCKER CARLSON: “I’ll be tormented for a long time by the fact that I played a role in getting Donald Trump elected. And I want to say that I’m sorry for misleading people.”
This is a very humble and honest statement. Big respect to Tucker.
What APAC Crypto Looks Like Today (vs the US)
1. Venture Capital (VCs)
- Many APAC VCs are slowing deployment and becoming more selective
- Shift from active investing → portfolio management / exits
- Some crypto-native funds are not raising new funds
Capital concentrated in:
- stablecoin
- RWA
- infra / compliance-related plays
vs US:
More funds still in active deployment cycles
Slightly broader experimentation (e.g. new primitives, prediction markets)
Read More 👇
HSBC completed its first public blockchain pilot on Canton Network.
Tokenised deposits. Atomic settlement. 24/7 real-time transfer across five major currencies.
The infrastructure is no longer being debated. It is being deployed.
There are two ways to touch 8 billion lives: acquire 8 billion individual customers, or build the infrastructure for the institutions that already serve them.
We chose the latter.
Today we're announcing OpenFX’s $94M Series A from @Accel, @atomico, @FactionVC, @M13Company , @northzoneVC, @PanteraCapital, and with support from existing investors @flybridge and @hash3xyz.
Introducing Paragon.
We build financial products from front of mind ideas. Starting with tickers every crypto trader already watches.
$BTC.D, $TOTAL2, and $OTHERS are now perpetual futures on @HyperliquidX.