A pharmacological arsenal without measurement is guesswork. A technological one without intervention is surveillance. The self-enhancer insists on both & that insistence is the whole shift now !
Armed with pharmacological levers and technological feedback, self-enhancers have collapsed the distance between how they feel and what is actually happening inside them
Every drug is approved against a disease, so every drug is measured against disease endpoints.
The effects that matter to a healthy person - body composition, cognition, sleep etc. sit in secondary endpoints. Underpowered, exploratory, honest about their own limits.
That's a real epistemic risk. It's also where most of the optimisation signal lives.
Hedonic engineering is the application of bioscience towards raising standards of mental health in the general population
Creative psychopharmacology can boost both drive and the capacity for incisive, goal-directed thought, in addition to sharpening, intensifying and diversifying our states of consciousness, hardly a proscription for a boring or incompetent life.
- David Pearce
Your thymus, the organ that trains your immune system starts shrinking after late 20's.
Chronic stress, bad sleep, and metabolic disease speed it up. India runs on all three.
We're not just getting sick. We're aging our immunity early.
Deep empathy, world-transforming creative energy, euphoric peak experiences and sublime states of blissful well-being can become the new norm of mental health
- David Pearce