Later this week, Vera Kiyasova, Director, Clinical Development, and Dan Brennan, Senior Vice President, Corporate and Commercial Strategy, will be heading to Orlando, FL for @CureSMA’s 2026 Annual SMA Conference. This is one of the leading events for the spinal muscular atrophy (#SMA) community, providing an important opportunity to strengthen our connections with individuals living with SMA, their families, clinicians, and fellow researchers, and we are proud to be a sponsor.
While at the conference, Vera and Dan will be presenting ‘An update on ignaseclant (NMD670): An investigational oral therapy enhancing activation muscle activation to improve strength, endurance, and daily function in adults with SMA’ during the Family-Friendly Poster Session. This #presentation will detail the latest updates on our SYNAPSE-SMA trial of ignaseclant, our first-in-class skeletal #muscle targeted therapy, in ambulatory adults living with SMA and will be available for view and discussion on 26 June from 6:30-8:30PM EDT in the Grand Harbor Ballroom. Jeff Selby, an NMD Adult SMA Patient Advisor who participated in the SYNAPSE-SMA clinical trial, will also be with Dan and Vera at the poster to discuss the importance of joining clinical research as a way to make an impact in moving #science forward toward more and better treatments for adults living with SMA.
In addition, we’re excited to be hosting a recognition buffet dinner event for individuals who participated in the SYNAPSE-SMA study, as well as caregivers and those who volunteered but were unable to directly participate in the trial. We hugely appreciate all those who take part in the #research process and look forward to formally recognising the significant contributions that they have made towards advancing our collective understanding of ignaseclant and its potential to improve the lives of people living with SMA.
Learn more about the conference here: https://t.co/Xb48GX0OM7
#CureSMA #SpinalMuscularAtrophy #Biotech #DrugDevelopment #NeuromuscularDisease #Conference
Over the weekend, NMD Pharma joined scientists, clinicians, and patient advocates at the 2026 @PNSociety1 (PNS) Annual Meeting in Maastricht, The Netherlands, where further safety and efficacy data from the Phase 2a SYNAPSE-CMT study evaluating ignaseclant in patients living with Charcot-Marie-Tooth disease (#CMT) was presented in a late-breaking oral #presentation by David Herrmann, MD, Chief of the Neuromuscular Division and Vice Chair for Strategic Initiatives in the Department of Neurology at the University of Rochester Medical Center.
Key findings showed that ignaseclant demonstrated consistent and sustained signals of benefit across multiple secondary functional endpoints. These improvements were observed in the CMT Functional Outcome Measure (CMT-FOM) composite scale at Day 7, which continued to improve further to Day 21 and sustained with statistical significance 7 days after treatment cessation. Similar patterns were also observed in hand grip strength, with additional improvement trends seen in the 9-hole peg test and lower limb outcomes.
Thank you to the PNS for the opportunity to share our #research with global experts, patients living with neuromuscular diseases, and patient advocacy organizations as we continue to advance our investigational first-in-class skeletal muscle activation enhancing oral drug therapy to improve muscle strength, function, important daily activities and quality of life.
Read the full press release here: https://t.co/cCWeRTZeBz
#PNS2026 #Conference #NMDPharma #Biotech #RareDisease #CharcotMarieToothDisease #CMTA #CMTRF #HNF #CMTFrance #ECMTF
Thomas Holm Pedersen, PhD, CEO of NMD Pharma, and Aldemar Degroot, PhD, VP, Business Development, will be in San Diego, CA from June 22-25 for the @IAmBiotech (BIO) 2026 International Convention, joining over 20,000 #biotech and #pharma leaders from around the world.
While at #BIO2026, Thomas and Aldemar will be available to discuss ignaseclant, our lead compound and first-in-class small molecule ClC-1 inhibitor, and provide updates on the broader NMD Pharma pipeline. In an exploratory Phase 2a study in Charcot-Marie-Tooth disease (#CMT), ignaseclant demonstrated consistent and clinically meaningful functional improvements across muscle strength, motor performance, and patient-reported outcomes. The Company is also conducting a Phase 2a study in adults with spinal muscular atrophy (#SMA), which has recently dosed its final participant, and a Phase 2b study in generalized myasthenia gravis (#gMG).
If you’re also planning to attend and would like to learn more, please reach out to [email protected] or via the BIO Partnering™ system to set up a meeting.
#NMDPharma #Innovation #BusinessDevelopment #DrivenbyPurpose
We’re pleased to announce that safety and efficacy data from the Phase 2a SYNAPSE-CMT study evaluating ignaseclant in patients living with Charcot-Marie-Tooth disease (#CMT) types 1 or 2, has been accepted for a late-breaking oral presentation at the 2026 @PNSociety1 Peripheral Nerve Society (PNS) Annual Meeting, being held in Maastricht, The Netherlands from June 13-16, 2026.
The presentation, entitled ‘Efficacy and Safety of Ignaseclant in Charcot-Marie-Tooth Disease: A Phase 2a Study’, will be given on Sunday, June 14 at 12.45pm CEST by David Herrmann, M. B. B. Ch., Chief of the Neuromuscular Division and Vice Chair for Strategic Initiatives in the Department of Neurology at the University of Rochester Medical Center.
In addition, Thomas Holm Pedersen, Chief Executive Officer, Ana de Vera, Chief Medical Officer, and Dan Brennan, Senior Vice President, Corporate and Commercial Strategy, from NMD Pharma will also be at the Conference to discuss our scientific progress, clinical plans and ongoing #ClinicalTrials in generalized myasthenia gravis (#gMG).
Discover the full #PNS2026 agenda here: https://t.co/4pLfCSlQSu
#NMDPharma #Conference #Biotech #Innovation #RareDisease #CharcotMarieToothDisease #ScientificResearch #NeuromuscularDisease
June is #MyastheniaGravis (#MG) awareness month, a time to raise awareness of this rare and chronic autoimmune disease that is estimated to affect more than 700,000 people worldwide.
In individuals living with MG, immunoglobin G (IgG) autoantibodies disrupt the normal communication between the nerves and muscles, which is important not just for mobility, but also for general healthy signalling involved in cardiovascular or gastrointestinal health, mood, cognition, diabetic control, and bone health. Over time, the cumulative impact of IgG attacks lead to structural changes in the muscle membrane which, along with the interrupted signalling, can cause ongoing, debilitating, and potentially life-threatening muscle weakness and fatigue that significantly impacts quality of life. MG commonly affects the muscles that contribute to proper eyesight, chewing, swallowing, and speaking and can also lead to difficulties with walking, running, or going up and down stairs. In addition, while MG is more commonly seen in adult women under 40 years of age and men aged 50 and over, it can occur at any age, including childhood.
There is currently no cure for MG, and despite the many approved therapies and medicines in development to address the autoimmune aspects of this #NeuromucularDisease, the associated muscle weakness and fatigue can significantly impact patients’ functional level and quality of life.
NMD Pharma is proud to be working on a skeletal muscle targeted drug therapy that has the potential to improve muscle strength and endurance, as well as restore the other aspects of normal nerve-muscle signalling that is so important to daily life. Our Phase 2b clinical trial is still enrolling for the next few months – if you are interested in taking part in this study you can “See if you Qualify” here: https://t.co/PlOSuPg5sZ
For more information: https://t.co/PGRRhKvlS0
#MyastheniaGravisAwarenessMonth #Innovation #RareDisease #Awareness
We’re proud to share an important milestone for NMD Pharma and the Spinal Muscular Atrophy (SMA) community: the final participant has been dosed our Phase 2 SYNAPSE-SMA clinical trial evaluating ignaseclant in ambulatory adults living with SMA Type 3.
We would like to thank all trial participants, families, investigators, study coordinators, and the broader SMA community for your support, commitment, and partnership throughout this journey. Your contribution is helping advance our understanding of ignaseclant and its potential to improve life for people living with SMA.
The study enrolled 52 participants across sites in the US and Europe. As we move into the next stage of the trial, our teams are working closely with investigators, data experts, and statisticians to ensure all study data are collected, verified, and analysed to the highest scientific standards.
We anticipate sharing an update on the SYNAPSE-SMA trial outcomes with the SMA community in the middle or late summer. If the results are positive, we look forward to working closely with people living with SMA, investigators, researchers, regulators, and the broader community to plan the next phase of clinical development.
Thank you to everyone who has been part of this important journey 🙏🏻
#SMA #SpinalMuscularAtrophy #ClinicalTrials #Biotech #DrugDevelopment #NeuromuscularDisease #ClinicalResearch
How do you get an extra dose of motivation in your workday?
At NMD Pharma, we recently had the immense pleasure of welcoming Stefan Bos, who lives with SMA, and his caregiver, Erna Speelman, who is also his mother, to our offices in Aarhus.
Stefan lives with spinal muscular atrophy (#SMA), but, as he puts it: “I have SMA, I am not SMA.”
During his visit, Stefan met with colleagues across #NMDPharma, toured our in-house laboratory facilities, and shared his personal story of living with SMA. He gave us valuable insights into his everyday life, what works, what does not, and what continued movement would mean to him.
Stefan also shared a message that resonated with all of us: “If you can help me keep the movement in my finger, support my voice, and support my breathing, I would be very appreciative.”
For our #scientists and teams working to advance small-molecule drug candidates designed to enhance #MuscleFunction and endurance in people living with #NeuromuscularDiseases, Stefan’s visit was a powerful reminder of why individual patient stories must remain central to #DrugDevelopment.
At NMD Pharma, we are dedicated to improving the lives of people living with neuromuscular diseases, and we value the voices, experiences, and perspectives of #Patients and #Caregivers. Their insights help shape how we think about research, clinical development, and the potential impact of our work.
Thank you to Stefan and Erna, for sharing your story, your valuable perspectives, and your world with us 🙏🏻
#SMA #SpinalMuscularAtrophy #NeuromuscularDisease #DrugDevelopment #RareDiseases #LifeSciences #PatientCommunity
NMD Pharma is excited to welcome Max Siller as Senior Scientist, based in our Copenhagen office, Denmark.
Max brings extensive experience in regulated bioanalysis across #preclinical and #clinical development, joining us from Ferring Pharmaceuticals, where he supported global development and clinical trial teams, including outsourced studies, bioanalytical method development, and regulatory submissions. His earlier roles in #DrugDiscovery and in vivo #pharmacology at AstraZeneca, Active Biotech, and AnaMar have given him broad expertise across the R&D value chain.
With an https://t.co/nsC7GCNn0y. in Molecular Biology from Lund University and a passion for high-quality science and collaboration, Max brings valuable expertise as we advance ignaseclant, our first-in-class skeletal muscle-specific ClC-1 ion channel inhibitor, through clinical development.
We’re thrilled to have Max on board and look forward to his contributions.
Welcome to the team!
#NMDPharma #NewHire #Careers #ClinicalDevelopment #LifeSciences #Biotech #Innovation
Please join us in wishing a warm #welcome to Anders Ulv Mandsholm, who joins NMD Pharma as IT Manager at our headquarters in Aarhus.
Anders brings extensive technical expertise as an IT System Manager and IT Business Partner, with a strong background in enterprise resource planning systems, business applications, and project and #ProgramManagement. With almost 20 years of experience, he has worked in system implementation, vendor management, and global IT operations, most recently at VOLA A/S and BioMar Group. We are thrilled to have him onboard and know that he will be a strong asset to our team!
Welcome to the team, Anders!
#NMDPharma #NewHire #Biotech #NeuromuscularDiseases #Career
Yesterday, Draupnir Bio, Teitur Trophics and NMD Pharma - together with ALBA – Aarhus Life science & Biotech Alliance and INCUBA A/S - had the pleasure of hosting representatives from the Business and Sustainable Development Department at Aarhus Kommune.
It was a valuable opportunity to discuss how we can strengthen the framework for life science and biotech companies in Aarhus, attract and retain critical talent, and ensure the right conditions for continued growth of a strong and competitive ecosystem.
We appreciate the open dialogue and look forward to continued collaboration.
#LifeScience #Biotech #Innovation #Aarhus
Last month, the #NMDPharma team participated in the Hereditary Neuropathy Foundation's (HNF) CMT Summit + Health & Wellness Retreat 2026, where Thomas Holm Pedersen, our CEO, had the honor of delivering the Welcome and Keynote Address. The opportunity to share our vision for the future of Charcot-Mariet-Tooth disease (#CMT) treatments, as well as an introduction to NMD Pharma and an update on progress with ignaseclant, our investigational skeletal muscle targeted drug therapy for patients with genetically confirmed CMT, with this engaged community was truly meaningful, but the real highlight for us was the opportunity to hear presentations and candid stories from patients living with CMT.
As proud sponsors of this Summit, we were energized by the collaborative spirit that defined the event. The combination of rigorous scientific discussion and genuine patient advocacy created an environment where real progress feels possible. We're grateful to the HNF for bringing the community together and for their continued leadership in advancing CMT #research.
#CharcotMarieTooth #Biotech #NeuromuscularDisease #PatientAdvocacy #HereditaryNeuropathyFoundation
Our CEO, Thomas Holm Pedersen, and VP, Business Development, Aldemar Degroot, will be heading to Prague, CZ next month to attend Bio€quity Europe, organized by @BioCentury.
If you are attending and interested in learning more about ignaseclant, our first-in-class ClC-1 inhibitor which has previously demonstrated clinically meaningful improvements across muscle strength, motor performance, and patient-reported outcomes in Phase 2 studies, then please connect via the partneringONE® platform or reach out to [email protected].
Looking forward to seeing you there!
#BioEquityEurope #NMDPharma #BioEquityEurope2026 #Biotech #Innovation #NeuromuscularDisease
Steen Saaby joins NMD Pharma as Scientific Director, API Development & Supply, based in Aarhus, Denmark.
Steen brings 20+ years of experience in small molecule chemical development and holds a PhD in Chemistry from Aarhus University. His experience spans process development, scale-up, technology transfer and commercial manufacturing, with a strong track record in advancing API development from early-stage to commercial readiness.
As we continue advancing ignaseclant through clinical development, we’re excited to welcome Steen to NMD Pharma.
Welcome to the team, Steen!
#NMDPharma #NewHire #Careers #DrugDevelopment #LifeSciences #Biotech #Innovation
Earlier in the week starting on Sunday afternoon, NMD Pharma joined patients, clinicians and advocates from across the myasthenia gravis (#MG) community in Hollywood Beach, Florida for the 6thAnnual @MyastheniaOrg (MGFA) National Patient Conference.
NMD Pharma’s Dan Brennan and our Patient Community Advisor Jeff Selby shared information at an exhibit table about the NMD Pharma SYNAPSE-MG clinical trial for those with generalized myasthenia gravis (gMG) that are experiencing muscle weakness and fatigue despite existing treatments. Jeff Selby an adult SMA patient who was a participant in the SYNAPSE-SMA clinical trial, helped engage in meaningful discussions with patients and caregivers about the experience of participating in #ClinicalTrials and the importance of participating in clinical research for new and unique treatments. It was great to see such strong engagement from the MG community, with many valuable conversations and a high level of interest in the study.
Thank you to everyone who stopped by to connect with us. We remain committed to advancing research, improving outcomes, and helping create a brighter future for people living with MG and other neuromuscular diseases.
For those with MG or their friends/family who would like to learn more about our SYNAPSE-MG clinical trial, please visit this site to “See if You Qualify”: https://t.co/nSmBGqMoYn
#MGFA #MyastheniaGravis #NMDPharma #NeuromuscularDisease #ClinicalTrials #Innovation
We’re thrilled to announce that the following NMD Pharma team members have been promoted: Anette Kjær Petersen, Senior Laboratory Technician, Beatriz Sevilla-Jensen, Clinical Trial Manager, Jesper Emil Jakobsgaard, Senior Research Scientist, Morten Dahl Sørensen, Senior Director, Medicinal Chemistry, Nicole Nicolajsen, Senior Administrative Coordinator, Vibeke Uhre, Senior Laboratory Technician.
Join us in congratulating them all on their promotions, and in wishing them the best of luck in their new roles!
Looking for a role in #biotech where your work truly matters? Browse our latest openings and learn how you could join a team committed to advancing care for people with neuromuscular diseases: https://t.co/CzSuXvPsqe
#CareerGrowth #Promotions #NeuromuscularDisease #Innovation #NMDPharma
New #job opening!
As we continue to advance our pipeline of novel therapeutics for neuromuscular diseases, NMD Pharma is looking to hire a motivated and highly skilled Communication Director to join our growing team. If you have experience in strategic communications within biotech, pharma or the life sciences, we’d love to hear from you.
Key responsibilities will include defining and executing NMD Pharma’s integrated corporate communication strategy, collaborating with external communications agencies and media partners and actively contributing to strengthening NMD Pharma’s internal communication culture and engagement.
The position will be based in either Aarhus or Copenhagen – find out more about the role, including necessary qualifications and key benefits, and apply online here: https://t.co/xYMY8yPfd2
To hear directly from one of our team members about what life is like behind the scenes at NMD Pharma: https://t.co/UjmmnMmdAz
#Hiring #Jobs #Innovation #Biotech #NeuromuscularDisease #Recruitment #publicrelations #communications
𝐍𝐌𝐃 𝐏𝐡𝐚𝐫𝐦𝐚 𝐜𝐨𝐧𝐭𝐢𝐧𝐮𝐞𝐬 𝐭𝐨 𝐞𝐱𝐩𝐚𝐧𝐝! With promising topline results from our Phase 2a study of ignaseclant in #Charcot-Marie-Tooth disease Types 1 and 2 announced earlier this year and the results of two further Phase 2 trials in generalised #myastheniagravis and #spinal muscular atrophy also expected this year, it is an exciting time to join our business.
We’re expanding our team and hiring a Translational Scientist – Muscle Biology to help drive our next phase of progress.
This is an opportunity to join a clinical-stage #biotech at a pivotal moment and contribute directly to the development of first-in-class therapies designed to restore skeletal muscle health and improve quality of life for people living with neuromuscular diseases. Key responsibilities in this role include designing, executing, and interpreting experiments in skeletal muscle #biology to support target validation, mechanism-of-action studies, and #preclinical candidate selection and turning complex biological data into clear insights that help guide both our current clinical studies and future research directions.
If you’re motivated by scientific rigor, collaboration, and the opportunity to make a meaningful impact for patients with high unmet medical needs, we’d love to connect.
Apply here: https://t.co/R849tAm2jf
#ClinicalDevelopment #NeuromuscularDisease #BiotechCareers #Hiring #LifeSciences #TranslationalScience #NewJob #JobOpportunity
#ICYMI, NMD Pharma has been invited to give two #presentations at the upcoming 2026 @MDAOrg (MDA) Clinical & Scientific Congress, being held at the Hilton Orlando, Orlando, FL from March 8-11.
The first, a late-breaking oral #presentation entitled ‘Efficacy and safety of ignaseclant in adults with Charcot-Marie-Tooth Disease: Top Line Results of a Phase 2a study,’ will detail further data from the Phase 2a SYNAPSE-CMT study evaluating ignaseclant (formerly known as NMD670) in patients living with Charcot-Marie-Tooth disease (#CMT) types 1 or 2. Topline results, which were announced last month, showed that ignaseclant was well-tolerated, with sustained improvements in objective functional measures and patient-reported outcomes. Taking place in Florida 4 at 2:15 PM ET on Wednesday, March 11, this presentation will be given by W. David Arnold, M.D., Executive Director of the NextGen Precision Health Initiative, Professor of Physical Medicine and Rehabilitation, Co-Director of Tom and Anne Smith MD/PhD Program, University of Missouri School of Medicine.
Earlier that day, CEO of NMD Pharma, @NMDpharmaThomas, will be giving an update on the ongoing Phase 2 SYPANSE-MG #ClinicalTrial of ignaseclant in patients living with generalized myasthenia gravis (#MG) who are AChR or MuSK antibody positive. To learn more, be sure to stop by Florida 4 at 9:00 AM ET on March 11.
Read the full press release here: https://t.co/Z9o3ldLScr
#MDA #MuscularDystrophyAssociation #Conference #Biotech #Innovation #NMDPharma #NeuromuscularDisease #MyasetheniaGravis #CharcotMarieTooth #RareDisease
We’re delighted to welcome Anne-Marie Larsen back to NMD Pharma as Principal QA Specialist.
Anne-Marie brings extensive quality experience across biotech and larger pharmaceutical organisations, covering GMP, GCP, GLP, GDP, and pharmacovigilance. Many will remember her from her previous time with us, where she played an important role in developing our Quality Management System during an earlier stage of our growth.
We’re very pleased to have her re-join the team and look forward to the expertise she brings as we continue to advance our pipeline.
Please join us in welcoming Anne-Marie!
#NMDPharma #Welcome #Biotech #Pharma #GMP #Pharmacovigilance #QualityManagement
The NMD Pharma team is growing!
As we advance our pipeline of small molecule inhibitors of skeletal muscle-specific ClC-1 ion channels into late-stage clinical development across #CMT, #MG, and #SMA, we’re expanding our team and hiring a Drug Substance Specialist in #SmallMolecules, to be based at either our headquarters in Aarhus or our office in Copenhagen, Denmark.
This is an opportunity to join a clinical-stage #biotech at a pivotal moment and contribute directly to the development of first-in-class therapies designed to restore skeletal muscle health and improve quality of life for people living with neuromuscular diseases. In this role, your main responsibilities will be to lead the drug substance #development program for our lead program, ignaseclant (formerly known as NMD670), from preparation for Phase 3 to commercialization, function as lead on other small molecule drug projects, in addition to establishing and maintaining strong collaboration with external partners and regulators.
If you’re motivated by scientific rigor, collaboration, and the opportunity to make a meaningful impact for patients with high unmet medical needs, we’d love to connect.
Apply here: https://t.co/9uQqehFkDF
#ClinicalDevelopment #NeuromuscularDisease #BiotechCareer #Hiring #LifeSciences #Job #NewJob