Storm Therapeutics

STORM Therapeutics is a biotech company discovering and developing novel small molecule therapies for RNA modification enzymes for oncology and other diseases

[Storm Therapeutics @storm_tx]

🚨 New data at #ASCO2026: First-in-class RNA-targeting therapy #STC15 shows early activity in #sarcoma.

📅 June 1, 1:30–4:30 PM CDT

🔗 Read more: https://t.co/I813wmNpyU

[Storm Therapeutics @storm_tx]

📢 We’ve announced a $56 million Series C financing to support the advancement of STC‑15, our first‑in‑class, oral small‑molecule METTL3 inhibitor. The first patient has now been dosed in a Phase 2 monotherapy trial in selected sarcoma indications. https://t.co/xC77sWmabt

[Storm Therapeutics @storm_tx]

Excited to team up with AlidaBio to explore how METTL3 inhibition affects RNA regulation in cancer patients. We're using AlidaBio's advanced sequencing platforms to analyze samples from our Phase 1/2 trials with STC-15, our first-in-class METTL3 inhibitor. https://t.co/P997pFOMRd

[Storm Therapeutics @storm_tx]

Meet STORM at @ELRIG_SCIENCE Drug Discovery 2025!

Join us for our poster presentations to explore the critical role of RNA-binding proteins in cellular replication stress mechanisms.

📍 Poster #163
📅 21 & 22 Oct
🕐 13:00-13:45 BST
📌 Beside the Tech Theatre

[Storm Therapeutics @storm_tx]

📢 Discovery data to be unveiled at AACR-NCI-EORTC 2025 📢

STORM Therapeutics will present new data on #STM11315, its allosteric, potent & selective #DHX9 helicase inhibitor, on 24 October.

🗣️ Oral Presentation: 5:26–5:36 PM EDT
📌 Poster Presentation: 12:30–4:00 PM EDT

[Storm Therapeutics @storm_tx]

📣 Appointment news from STORM!

We're excited to welcome veteran cancer drug developer Eric Martin as Chief Development Officer as we advance our METTL3 inhibitor STC-15 through Phase 1b/2 development.🔗 Learn more: https://t.co/kCHT6of13w

#oncology #biotech #drugdevelopment

[Storm Therapeutics @storm_tx]

Clinical milestone achieved & CMO appointed! The #firstpatient has been dosed in our collaboration with Coherus Biosciences, commencing a Phase 1b/2 study with STC-15 in combination with Coherus’s next generation PD-1 inhibitor, LOQTORZI® (toripalimab). https://t.co/BgAVrDadYm

[Storm Therapeutics @storm_tx]

Look out for the #STORM team at London Life Sciences Week! Our CEO, Jerry McMahon, will attend the upcoming @Jefferies London Healthcare Conference from 19-21 November alongside our CBO, Marguerite Hutchinson.

[Storm Therapeutics @storm_tx]

Our Group Leader, Molecular Cell Biology, Alexandra Sapetschnig, is presenting at RNA Modifications and Epitranscriptomics on 15 November from 11:20-11:40 CET! Come along to hear about #STORM's first-in-class #METTL3 inhibitor #STC15 and new #clinical data presented at #SITC2024.

[Storm Therapeutics @storm_tx]

Check out the latest insights from our CEO, Jerry McMahon, featured in an article by International Clinical Trials discussing the current field of Alzheimer’s disease, drugs, biomarkers, and the future of treatment options for #neurogenerativediseases: https://t.co/TqVeMENHlT

[Storm Therapeutics @storm_tx]

Read the press release here: https://t.co/WPPRx4JiWA

[Storm Therapeutics @storm_tx]

#STORM presents new #clinical data at #SITC2024 from its Phase 1 study evaluating #STC15. Highlights include promising signs of clinical activity observed in multiple tumor types and gene expression data showed upregulation of innate immunity pathways. Read more in the comments👇

[Storm Therapeutics @storm_tx]

Visit our poster presentation at #SITC2024!

📝 Title: Phase 1 dose escalation and cohort expansion study evaluating safety, PK, PD and clinical activity of STC-15, a METTL3 inhibitor, in patients with advanced malignancies
📅 Date: Saturday 9 November
📌 Abstract number: 676

[Storm Therapeutics @storm_tx]

STORM is in Barcelona for the EORTC-NCI-AACR (#ENA) Symposium! Poster details below 👇

📢 Session Title: New therapies in immuno oncology
📅 Session Date and Time: 25 October, 09:00 - 15:00 CEST
🏢 Location: Exhibition Hall
📌 Catalog Number: 451
🗞️ Presentation Number: PB439

[Storm Therapeutics @storm_tx]

Thanks to @Cambridge_Uni for spotlighting us as one of '10 Cambridge spinouts changing the story of cancer'!
Check out STORM in the article 👇 and discover how we are pioneering cellular reprogramming through RNA modifications to treat disease🧬#lifesciences #biotech #cancer

[Cambridge University @Cambridge_Uni]

💡A brilliant idea for helping cancer patients is just that – an idea – until it is put into practice.

Here's how 10 companies spun out of research at Cambridge are doing it:
https://t.co/sR3SESXxzS

#ChangingTheStoryOfCancer

[Storm Therapeutics @storm_tx]

Read the press release here: https://t.co/CaHoUyRZVn

[Storm Therapeutics @storm_tx]

#STORM is presenting a poster on its updated interim results from its ongoing Phase 1 trial with lead product, STC-15, at the ENA Symposium! STC-15 is a potent and selective oral small molecule that inhibits METTL3.

💡 Find out more in the press release linked in the comments.

[Storm Therapeutics @storm_tx]

Meet the #STORM team at @ELRIG_UK Drug Discovery 2024 on the 📅2-3 October at the 📍ExCel in London, where will be presenting the poster, 'Working towards pandemic preparedness: Inhibiting viral 5' RNA cap methylation with potent, selective, broad-spectrum small molecules'.

[Storm Therapeutics @storm_tx]

Our CEO, Jerry McMahon, provides insight into the potential of STORM's lead product STC-15 "across multiple therapeutic areas" in @DDWJournal's article which delves into the new mechanisms of action, receptors and modalities in cancer immunotherapy, here: https://t.co/XTR11sq1un

[Storm Therapeutics @storm_tx]

#STORM's Senior Vice President Therapeutics, Matthew Fyfe, is chairing a session at the International Symposium on Medicinal Chemistry!

📢 Title: Session 4 'Chemical Biology': Targeting RNA and RNA-Regulatory Proteins
🕐 Date & Time: 2nd September, 13:45 CEST
📍 Rome, Italy