Bjørn Olav Bøe

Status viatoris, just like you

[Bjørn Olav Bøe @stprest]

@amazing_physics T

[Bjørn Olav Bøe @stprest]

@MagneBjella Fornuftig!

[Bo Wang @BoWang87]

This is really cool (and wild):

Scientists simulated a complete living cell for the first time. Every molecule, every reaction, from DNA replication to cell division.

The paper (Luthey-Schulten et al., Cell 2026, https://t.co/PXxXWKC8yp), just out today, used JCVI-Syn3A — a synthetic minimal bacterium with fewer than 500 genes. A 3D+time simulation of the full 105-minute cell cycle: DNA replication, protein translation, metabolism, division. Every gene, protein, RNA, and chemical reaction tracked through physical space.

It took years to build. Multiple GPUs. Six days of compute time per run.

And this is the simplest possible cell.

A human cell has ~20,000 genes. It lives in tissue. It interacts with neighbors. It differentiates. It responds to drugs in ways that depend on context we haven't fully measured.

Mechanistic simulation of the minimal cell costs 6 GPU-days for 105 minutes of biology. You cannot scale that to human cells. The complexity isn't 40x harder. It's exponentially harder.

This is why the field pivoted to data-driven models. You can't hand-encode the regulatory wiring of a human hepatocyte. But you can learn it — if you have the right perturbation data collected across enough diverse biological contexts.

The two approaches aren't competing. Papers like this generate the ground truth that future ML models need for validation. But the path to a clinically useful virtual cell runs through foundation models, not through scaling up mechanistic simulation.

Amazing work!

[Tansu Yegen @TansuYegen]

Incredible footage from the perspective of wild mountain goats with cameras attached; they're literally flying without wings.

[Vala Afshar @ValaAfshar]

Isaac Asimov's three laws of robotics, 1965

[Bjørn Olav Bøe @stprest]

@vebjornselbekk Det avhenger vel helt av hva som skjer videre…?

[Tom Nichols @RadioFreeTom]

@WarintheFuture A farrago of charges and goals, but no actual identification of an end state that would tell us when we're done

[Brian Roemmele @BrianRoemmele]

A generation…

[Tall Kogi Man @TallShortKing]

They don't make comedy like this anymore

[Captain Dave @DaveWallsworth]

It’s now 40 years since this quite brilliant episode of Yes, Prime Minister was broadcast but somehow it still seems remarkably appropriate after all this time! One of the best comedy series ever and superbly acted.

[Bjørn Olav Bøe @stprest]

@elonmuskPBG 2

[Vala Afshar @ValaAfshar]

“It will never get easier. What happens is you handle hard better.”

—Kara Lawson, head coach @DukeWBB

[Jonny G 🇺🇦 @dontforgetchaos]

I make no apology for posting this photo. I think it’s a photo that will haunt America in the years to come.

This is what you have become. If you defend this, have a word with yourself.

[Bjørn Olav Bøe @stprest]

Det er bemerkelsesverdig å se titalls millioner kristne rettferdiggjøre, overfor seg selv og hverandre, en politisk bevegelse ledet av en ondartet narsissist – drevet av hat og hevnlyst, som håner de døde og fryder seg over å påføre de maktesløse smerte.

[Bjørn Olav Bøe @stprest]

@Elonmusklona Sure! 👎

[Ounka @OunkaOnX]

The reason why Venezuela is under attack

U.S. Southern Command chief General Laura Richardson just said the truth out loud:

the U.S. focus in Latin America isn’t “democracy” — it’s controlling oil, lithium, gold, and rare earth minerals. Venezuela, with the largest oil reserves and key strategic resources, is the main target

[Bjørn Olav Bøe @stprest]

@KaterynaLis So true!

[Bjørn Olav Bøe @stprest]

@ElonMuskNews47 42

[Bjørn Olav Bøe @stprest]

@Anaya__ Have you seen me?

[Bjørn Olav Bøe @stprest]

@elonmuskTN It’s a face