Have you looked at the research of Alain Jacquet?
He's done incredible work on innate immune system activation by dust mite allergens(which are ubiquitous in our homes, and we are exposed frequently in large amounts)
https://t.co/9ySorawkQy
There are also challenge studies showing inhaling dust mites can cause e.g. eczema, suggesting it could be affecting the entire body.
https://t.co/fXzFJ8GvHT
Would love to hear if you have any insights on whether there's a connection here.
Migraines have a high overlap with the allergic diseases(over 2x chance of migraines with allergic rhinitis, +50% chance witt asthma):
https://t.co/cnYxhBlHTC
Allergic diseases are mainly caused by dust mites, your home is likely filled with their toxins and you breathe them constantly.
They cause damage to your immune sytem that goes beyond the common idea of allergies, which worsens your outcomes from many health conditions.
You can kill all the dust mites in your home by controlling humidity, then if you clean out all the toxins that hae built up over the years you can drop your exposure dramatically.
If you hold 40% humidity in your house it will pause their lifecycle(which stops new allergens) in the short term, and in the longer term(1-2yrs) it will kill the hibernating colony.
After that, you reduce the amount of allergens in your house by cleaning(launder at 150 degrees), removing contaminated items, and get allergy covers to encase your mattress and pillows.
The allergens have built up in all the permeable items in your house over the years. Curtains, carpets, clothes, book, furniture etc.
@lennysan Super cool! Don’t forget about dust mites - The indoor toxin that causes the highest amount of disease burden of anything else, and the most ubiquitous.
@m0ldilocks Same thing with dust mites! From the research you can see massive numbers of people affected, and the severity. It dwarfs anything else, and yet hardly anyone seems to think it’s their problem.
Very interested in this subject as well.
There is something happening for frontier users that looks like AI workflows decoupling from the OS.
The hardware requirements will trend toward simplicity: storage for a small amount of data, local STT inference, maybe multiple devices for output.
Which should open up the possibility of other hardware.
A few trends along the way:
less work done in apps and websites
demand for full programmatic access to features(neither OS nor apps nor most products are that good at this)
customized workflows that you change by talking to them(probably accomplished in the near term by agents customizing themselves rather than somehow training on your preferences)
not sure where this ends up, or how it results in new hardware products, or how it gets back to larger audiences.
A current favorite use for claude code is proactive PT. I've been in PT twice in the last few years, but why not find and correct issues that aren't yet injuries?
The agent makes it really easy to maintain the plan, access it when you want to use it, iterate on it, try new assessments, etc.
Really cool accomplishment! I hope you will look into dust mites as the cause of your asthma(and digestive issues and more). There is tons of excellent evidence for this. Most people breathe their toxins in all the time at home, and it causes several problems like asthma for millions. It's possible to completely remove them from your home and will likely greatly improve your health.
The number of people affected is so huge - if you are sicker than usual, or suffer from conditions with no known cause, or spend more time in bed than usual, Bayes law says it's likely this is your problem.
Dust mite feces is highly evolved to make you sick. It causes some problems directly, but it also damages the immune system across your entire body, making you more vulnerable to everything else. The goal is to keep you in bed so dust mites can feed on you more. Almost all homes are filled with their allergens, and it's making millions of people extremely sick, but everyone gets diagnosed with countless conditions across the body with "no cause and no cure"
For dust mites -
20-50% of the dust in your house is shedded human skin. It soaks into all the porous items in your house over years. Dust mites transform it into fecal pods which you then breathe in constantly.
if you drop humidity to 40% they will immediately stop producing new allergens( then the adults will die within days, and the rest of the colony(eggs nymphs will die out after a year or so) , but then all your stuff and carpet/curtains/cloth covered furniture is still soaked in their allergens. But if you clean or remove all the contaminated items you can drop dust mite exposure to zeroish. Laundry at 150 degrees is the most practical tool for removing allergens from small fabric items. Allergy cover around the bed to lock in existing allergens b/c it’s the biggest resevoir. Get rid of all low value porous items(like rugs or carpet)
After controlling humidity, items will no longer get contaminated going forward, but old items have been building up allergens for years and should be considered damaged.
IME once you stop the constant exposure at home the epithelial damage will heal within weeks and then you will be more resilient to exposure outside your home.
@nikitabier@GWHayduke97 This is caused by dust mite poisoning! You should try getting dust mite allergens out of your home. If you have any of: chronic cough, digestive issues, allergies, eczema, low vitamin D, or are more prone to sickness than most, it's even surer it would be helpful to you.