like no hate no shade but character design is intentional and tells you about the nature of each character. if you cant replicate that with actors, theres gonna be some visual dissonance. if your character is supposed to be intimidating but your actor isnt, you lose the effect.
there are elements of animation that are unique to it and not replicable (or hard to replicate) in live action. if you wanted to make a live action show to off some cool cgi tricks, maybe make an original story.