Systems and Signals

@syssig.bsky.social mtDNA, nets, noise, inference | @IX_AI_SciCentre @ImperialX_AI @ImperialMaths

[Systems and Signals @sys_sig]

Systems and signals group at @ImperialMaths led by Nick Jones. Stay tuned for our latest research on #mitochondria #aging #genetics #biomathematics #physicalbiology #networks and #ML.
We blog regularly https://t.co/OP2yt4PBI5 and there's more info at https://t.co/jk3uGpFUHL

[Systems and Signals @sys_sig]

Our paper 'Cryptic mitochondrial DNA mutations coincide with mid-late life and are pathophysiologically informative in single cells across tissues and species' https://t.co/o4eb5WWzlM now out in Nature Communications. See our thread on bsky

[Systems and Signals @sys_sig]

We will begin the switch over to other social media and have a blueskye account @syssig.bsky.social

[Systems and Signals @sys_sig]

Calorie restriction (CR) is known to improve healthy ageing and we find indications that CR rats have lowered levels of cryptic mtDNA mutations. CR can increase mtDNA numbers and our theory predicts that higher mtDNA copy-numbers slow accumulation of mtDNA mutations. 6/6

[Systems and Signals @sys_sig]

We decided to readvertise our exciting paper 'Cryptic mitochondrial ageing coincides with mid-late life and is pathophysiologically informative in single cells across tissues and species' 1/6 https://t.co/U3xtE5qT2p

[Systems and Signals @sys_sig]

Over 7 datasets, in multiple tissues in humans, mice and rats, cells with cryptic mtDNA mutations have gene expression changes consonant with ageing including immune effects and protein misfolding. We give experimental corroboration in human cell lines. 5/6

[I-X @ImperialX_AI]

🌟 Six 4-year Independent Fellowships dedicated to AI in Science in a program supported by Schmidt Sciences and Imperial College London (offered through @imperialcollege Research Fellowships).

🗓 Deadline: 19 August

🔗 Read about the fellowships ➡ https://t.co/W7qkBrrDs5

3/3

[I-X @ImperialX_AI]

🌟 Ten 2-year Independent Fellowships dedicated to AI in Science in a program supported by @schmidtsciences:

➡ Eight 2-year Eric and Wendy Schmidt AI in Science Postdoctoral Fellowships.
➡ Two 2-year Chapman Schmidt Fellowships.

🗓 Deadline: 20 September

2/3

[I-X @ImperialX_AI]

📢 Job Alert: 16 Independent Fellowships in AI in Science!

The @IX_AI_SciCentre seeks 16 new fellows to join their prestigious programme and accelerate artificial intelligence research in Engineering, Natural and Mathematical Sciences.

How to apply: https://t.co/Dp3K15B0Yk

1/3

[Systems and Signals @sys_sig]

A fun video introducing I-X https://t.co/KleC4u3CN2 @ImperialX_AI @IX_AI_SciCentre

[Systems and Signals @sys_sig]

Please circulate: new I-X lectureship in I-X and Imperial Statistics: https://t.co/8Am6dVfASs @ImperialX_AI learn about I-X here https://t.co/hWyBdMzTYF

[Ben Fulcher @bendfulcher]

Work by @olivercliff @AnnieGBryant @NaoTsuchiya @jlizier published today in @NatComputSci !

Article link: https://t.co/XOxPeSmAKi

And thanks to @jkbren for a really clear and thoughtful commentary: https://t.co/RU83g92n5B

[Systems and Signals @sys_sig]

Work by @FerdinandoInsa1 on boosters for COVID19 versus Delta/Omicron, with great @UKHSA collaborators. https://t.co/DktqvFNkOc Boosters work, but protection wanes in ~4 months highlighting the need for continuous monitoring of vulnerable people and for correlates of protection.

[I-X @ImperialX_AI]

📌JOB VACANCY: Senior Teaching Fellow

We are looking for a Senior Teaching Fellow who will have a key role in the training of the @IX_AI_SciCentre Fellows and developing our educational programmes within I-X.

Deadline: 26 Oct
Apply below⬇️

https://t.co/Y3GCZfNVx2

[I-X @ImperialX_AI]

📢11 new independent Fellowships in #AI in #science are now open for applications👏

Don't miss out on this fantastic opportunity to be at the forefront of @imperialcollege #AIresearch 🤖

⬇️Find out more & apply
https://t.co/Dp3K15B0Yk

@ImperialAI @ImperialDSI @ImperialSci

[I-X Centre for AI in Science @IX_AI_SciCentre]

@SchmidtFutures @ImperialX_AI Coming Soon...

Launching in August, there will be a further round of up to 8 two-year #AI in Science #fellowships.

These are flexible & independent and you will be joining a cohort of top scholars based in @ImperialX_AI!

Keep an eye out here ⬇️
https://t.co/5OprAOvrOD

[I-X Centre for AI in Science @IX_AI_SciCentre]

Applications are now open for 3 independent 4-year fellowships dedicated to #AI in Science & supported by @SchmidtFutures

Based in @ImperialX_AI, these prestigious Imperial College Research Fellows will be given bespoke training & 121 career development

https://t.co/B6oOz6wVbG

[Systems and Signals @sys_sig]

An exciting AI in Science themed independent fellowship for two years joint between the African Institute of Mathematical Sciences in Kigali and Imperial. @ImperialX_AI @AIMS_Rwanda

[I-X @ImperialX_AI]

📢Don't miss out on the AI in Science Postdoctoral Fellowship between London & Kigali: based at @imperialcollege in I-X for the first year & @QL_Africa, @AIMS_Rwanda for the second.

Support from @SchmidtFutures & @CarnegieCorp

Deadline: 31 May
@AIMS_Next
https://t.co/CJXWY2WLYd