FMO3 Metabolic Malodor (mostly sulfides + TMAU ?)

Metabolic body malodor
FMO3 malodor = 99%?
5%+ 'at risk' ?
TMAU is severe type ?
most = sulfides malodor
Likely cures
to tests

[FMO3 Metabolic Malodor (mostly sulfides + TMAU ?) @systemicBO]

not posted much on TMAU ...

E.esperance probiotic project for TMAU (and probably FMO3 Malodor) is so perfect, there's no urge to plead to world anymore.

just a case of waiting year or 2.
base price is like $10/week

https://t.co/M9YYhZhWQF

[FMO3 Metabolic Malodor (mostly sulfides + TMAU ?) @systemicBO]

only 30 grams of unabsorbed carbs can allow gut bacteria to produce over 10 liters of gas in the intestines

[FMO3 Metabolic Malodor (mostly sulfides + TMAU ?) @systemicBO]

Read the Fast Tract Digestion IBS book for more information about FP and its dietary solution. When you are ready to implement the solution, use the Fast Tract Diet app.

[FMO3 Metabolic Malodor (mostly sulfides + TMAU ?) @systemicBO]

FP = Fermentation Potential : a point system that measures symptom potential (low, medium, high) based on amount of offending fermentable carbs that feed gas and symptom-causing bacteria in each condiment, food, drink, and even supplement vs. how much they absorbed into blood.

[FMO3 Metabolic Malodor (mostly sulfides + TMAU ?) @systemicBO]

Hydrogen gas is the hallmark of SIBO/IBS-D (diarrhea). It feeds archaea, and well-fed archaea produces methane, leading to IMO/IBS-C (constipation).

H gas also feeds hydrogen sulfide producing bacteria, leading to bloating (77.0%), constipation (50.8%), and ab pain (50.8%)

[FMO3 Metabolic Malodor (mostly sulfides + TMAU ?) @systemicBO]

Fmo induction as a tool to screen for pro-longevity drugs
Leiser et al.
University of Michigan (Aug24)

https://t.co/Wt2wgLcN5n

[FMO3 Metabolic Malodor (mostly sulfides + TMAU ?) @systemicBO]

Flavin-containing monooxygenases (FMOs) are highly conserved xenobiotic-metabolizing enzymes with a clear role in promoting longevity in nematodes and a plausible similar role in mammals.

[FMO3 Metabolic Malodor (mostly sulfides + TMAU ?) @systemicBO]

is it you that's hungry ?
or your out of control microbiome ?

e.g.
SIBO
colon dysbiosis

Ab ultrasound should spot

[FMO3 Metabolic Malodor (mostly sulfides + TMAU ?) @systemicBO]

imho thesis

1. our microbiome is overfed (eg SIBO)
2. permanent fermentation (gas. drunk)
3. acutely prone to d-lactic acidosis (ask a farmer)

Dr Norm Robillard is worth listening to on gut microbiome (maybe even he underestimates, eg jasmine rice)

https://t.co/Wbniufy4zf

[FMO3 Metabolic Malodor (mostly sulfides + TMAU ?) @systemicBO]

thesis :
1st test for dysbiosis and/or FBO should be ab ultrasound scan ?
to look for gas.
in the colon ? up in small intestine ?

sadly we dont live in sensible world for such problems.
horses get checked, but humans are just to get on with it.

[FMO3 Metabolic Malodor (mostly sulfides + TMAU ?) @systemicBO]

good news ... slower but still good 👍
"Unfortunately, we are far from having a purchasable product. We are still in the lab experiment stage of development. Research on the cell-based therapeutic is continuing within the Institute for Pediatric Rare Diseases here at FSU."

[FMO3 Metabolic Malodor (mostly sulfides + TMAU ?) @systemicBO]

FSU IGEM 23 project : E.esperance 'probiotic' for TMAU (TMA metabolizer)

Dunno if anyone is still working on it (it was student project).
asking around...

https://t.co/BnEszw5PCA

[FMO3 Metabolic Malodor (mostly sulfides + TMAU ?) @systemicBO]

podcast with E.Esperance team member (Jan 24)
not heard much since.

Probiotic to metabolize Trimethylamine.

The InNOLEvation® Mindset (S5E7): Tackling Fish Odor Syndrome - Sai Devulapalli of E. esperance https://t.co/F0NMEe56VJ via @ListenNotes

[FMO3 Metabolic Malodor (mostly sulfides + TMAU ?) @systemicBO]

general health article ..
intermittent fasting .. like 5:2 or 16:8

sounds plausible ???

https://t.co/3ZTv4Sv9YC

[FMO3 Metabolic Malodor (mostly sulfides + TMAU ?) @systemicBO]

ORD cases are probably mostly FMO3 Malodor cases
ORD is flagship of craziness of psychiatry ?

https://t.co/vLQwZZAaou

[FMO3 Metabolic Malodor (mostly sulfides + TMAU ?) @systemicBO]

ORD myth ..

"Olfactory reference disorder (ORD) is a mental illness in which individuals overestimate their sense of smell and worry about the negative impact of odors...
Using this model, this study reports a successful treatment process of a 53-year-old female with ORD"

[FMO3 Metabolic Malodor (mostly sulfides + TMAU ?) @systemicBO]

"7-sessions intensive intervention over 3 weeks, her symptoms of ORD, anxiety,depression reduced. High-frequency CBT practices could be beneficial in treatment of patients with severe ORD, facilitating rapid improvement in both ORD symptoms and functioning."

crazy shrinks ?

[FMO3 Metabolic Malodor (mostly sulfides + TMAU ?) @systemicBO]

https://t.co/BFxJKM0ROf

[FMO3 Metabolic Malodor (mostly sulfides + TMAU ?) @systemicBO]

ORS myth Japan style ...

"In the 1960s and 1970s, there was widespread discussion in Japan about the pathological experience of "unpleasant odors emanating from one's body." This symptom is called "Jikoshu"

[FMO3 Metabolic Malodor (mostly sulfides + TMAU ?) @systemicBO]

likely :
all probably have transient FMO3 Malodor

for ORS .. all should be tested :
FMO3 gene
TMAU

TMAU not best biomarker test (only spots severe's) but all we have.

ORS diagnosis likely shows up how crazy our Psychiatry Systems are