aln🇺🇦

Systems Biology, Bioinformatics and other fun things🥃
Mastodon: @[email protected]

[aln🇺🇦 @systemnaBio]

First keynote at #ISMBECCB2025 #Liverpool #deepmind #alphafold!

[Brad Krajina @BradKrajina]

Select your cell: I'm prototyping an interactive sc RNA-seq portal where the UMAP is dynamically linked to morphing 3D artistic renders of each cell type. You can play with the initial build below.

[Ihor Lachenkov @igorlachenkov]

Center of Kyiv, two Russian missiles hit a regular residential area

[scverse @scverse_team]

anndata 0.12 is out now! We have lots of great features that we hope address some persistent needs. Here are some of the highlights!

[Heng Li @lh3lh3]

We often talk about pangenome reference but what does "reference" mean? If it means the whole graph, what is a variant? My collaborators Pouria and Luke give a clean answer: the reference is a spanning tree including GRCh38 and variants are leftover edges. See preprint for more.

[Luis Pedro Coelho @luispedrocoelho]

The 19th International Conference on Data and Text Mining in Biomedical Informatics,

15-18 December 2025 (Muju, Republic of Korea)

I will be a speaker!

https://t.co/hqF62ImHFZ

[Luis Pedro Coelho @luispedrocoelho]

Latest preprint from the lab (and the last chapter from Shaojun Pan's PhD thesis)

Making strobealign nimbler and faster!

https://t.co/JPRDRxgYke

[Maria Drutska 🇺🇦 @maria_drutska]

Russia killed 31 people in Kyiv yesterday night. Among them were five children.

The youngest victim was just two years old.
159 people were injured, including 16 children.

🕯️

[Olena Halushka @OlenaHalushka]

The death toll from yesterday's barbaric russian attack on Kyiv has risen to 31 — including five children.

[Luis Pedro Coelho @luispedrocoelho]

Re-reading an old grant proposal (from 2023) and marveling that we used to write these without LLMs

[CAMDA 2025 @CAMDA_conf]

And the #CAMDA25 team continues with the celebration (including a visit to the super lambanana), wishing them all the best and looking forward to seeing you next year in the #ISMBECCB2025

[Irina Kostyshina 🇺🇦 🩷💜💙 @irinikostyshina]

А порадьте якийсь хороший наукпоп (можна англійською) на фізичну тематику, щоб позакривати в голові різні прогалини, які лишилися зі школи

[Costa Lab - @costalab.bsky.social @vanvanka123]

Celebreting a busy & sucessfull #ISMBECCB2025

[CAMDA 2025 @CAMDA_conf]

Kinga Zielińska (Jagiellonian Univ.) opens the #CAMDA25, #ISMBECCB2025 the Gut Microbiota Challenge: Can we build a better microbiome health index? With 4,398 samples & taxonomic + functional data, participants are encouraged to go beyond GMHI & hiPCA

[CAMDA 2025 @CAMDA_conf]

David Danko (Biotia Inc.) presents BIOTIA-DX Resistance at #CAMDA25, #ISMBECCB2025, a clinically validated metagenomic workflow adapted for AMR prediction. With curated global data and stringent preprocessing, the tool reached an F1 score of 84 on the challenge test set

[CAMDA 2025 @CAMDA_conf]

Owen Visser (Univ. of Florida) presents an ensemble ML model for AMR prediction at #CAMDA25, #ISMBECCB2025. Trained on strain-specific markers & AMR gene classes, achieving up to 98.2% accuracy (A. baumannii). Permutation analysis reveals key resistance genes in diverse pathogens

[CAMDA 2025 @CAMDA_conf]

Jack Vaska (Stony Brook Univ) applies LLMs to #AMR prediction at #CAMDA25: Fine-tuned DNABERT2 models + DBGWAS identify resistance-linked sequences across 9 pathogens & 4 antibiotics. Results show high accuracy, showcasing the power of deep sequence context in AMR genomics.

[CAMDA 2025 @CAMDA_conf]

Now, Alper Yurtseven (Helmholtz Institute) tackles #AMR at #CAMDA25, #ISMBECCB2025 by predicting resistance across 9 key bacterial species using machine learning. With a focus on scalable, cross-species models in the fight against antimicrobial resistance.

[Mina Shaigan - @minashaigan.bsky.social @MinaShaigan]

🔬 Ever wonder how your immune system ages?
📊 We used single-cell multi-omics (RNA + ATAC) + bulk ATAC on PBMCs to build a cell-by-cell map of aging.
🧠 Find out which genes fade, which chromatin gates close and why some immune systems age slower.
👉 Poster C-482 #ISMBECCB2025

[Jason "boundless delight " Williams @JasonWilliamsNY]

Honored to open day two of #BOSC2025 and BOKR joint session at #ISMBECCB2025 introducing @chrismungall opening keynote: Open Knowledge Bases in the Age of Generative AI

[Costa Lab - @costalab.bsky.social @vanvanka123]

A strong tour by @GiuliaCesaro4 on cell cell Communication and intra celular signaling at ISMB