Tainla Jamir

Just a regular person from India’s incredible North-East. No trains & Dms| Making life multi-planetary| Hey Charlie, we’ve got it from here| MAGA 🇺🇸🇮🇳🇮🇱

[Tainla Jamir @tainla_jamir]

@Christi26046713 “The woods are lonely, dark and deep,
But I have promises to keep,
And miles to go before I sleep,
And miles to go before I sleep.”
- Robert Frost
🫂✝️

[John Kenney @jlkenney3]

@paulg The Left / Media is completely blinded by ideology. They cannot evaluate even the most basic things, except through heavy, heavy ideological filters.

[LB @CanadaFirst78]

@paulg They wanted this to happen so bad, now it is the defacto place to debate and discuss. The left hates it, I love it. The truth will always prevail!

[Tainla Jamir @tainla_jamir]

@army1325air God bless you, Sir. 🫡

[Tainla Jamir @tainla_jamir]

@doogadoo11 A mercenary attitude.

[Cynical Publius @CynicalPublius]

I feel that the 25th anniversary of 9/11 has caused a critical mass of Americans to reach an inflection point on their understanding of that event.

We are starting to realize that we lost the Global War on Terror. We did not lose it on military grounds. We lost it on spiritual grounds. Domestically we are succumbing to the goals of Sharia and jihad, which was EXACTLY what the 9/11 terrorists sought to bring about with their heinous actions.

Now that more and more people are seeing this, we can combat it--not with tanks and bombs and rifles alone, but with our words, voices and votes.

We must actively combat the Islamification of America. Sharia and jihad are wholly incompatible with the Constitution. Islam is a political movement hiding beneath the cover of freedom of religion. When a "religion" itself is not free, it is no longer a religion and no longer enjoys the protections the Constitution affords.

Spread the word.

[Doog @doogadoo11]

For all the people threatening to sit out the midterms because Trump hasn't solved 250 years' worth of problems in 20 months

Just know, there is no sitting out

You're actually just voting for:

- Open Borders
- Sharia Law
- Communism
- Higher Taxes
- More Crime
- Etc

[Tainla Jamir @tainla_jamir]

@StevenDughetti Congratulations! 👼🏻😇💫🥰

[The_Patriot_Guy @The_Patriot_Guy]

I just recieved her paw prints. I saw someone say, and it's so true.
"For a brief moment in time, they are your best friend, but to them, you're their best friend for a lifetime. 😓

[Tainla Jamir @tainla_jamir]

@The_Patriot_Guy I’m so sorry for your loss, my friend.
🐕🐶💔🐾🖤✨💫🌈🕊️🐶🐕🫂

[Tainla Jamir @tainla_jamir]

@The_Patriot_Guy Thanks! Glad to hear it! Everything is great on my end as well. 🤗

[Tainla Jamir @tainla_jamir]

@doogadoo11 I don’t get it either 🤷‍♀️

[ARMY1325AIR @army1325air]

343 firefighters walked into hell on September 11, 2001 knowing damn well what they were walking into.

They ran toward danger while everyone else was trying to escape.

343 never came home.

Remember their courage. Remember their sacrifice. Remember every innocent life taken that day.

America, never forget.

[Tainla Jamir @tainla_jamir]

@army1325air 👩‍🚒❤️🇺🇸🫡

[Tainla Jamir @tainla_jamir]

@The_Patriot_Guy I know, it has been forever! Great to see you too! How have you been?

Sorry for the late response. 🙏🤗

[Tainla Jamir @tainla_jamir]

We love you, Charlie. You are so missed.

✝️💔🇺🇸

[Tainla Jamir @tainla_jamir]

@army1325air Smile 🤗

[Tainla Jamir @tainla_jamir]

@doogadoo11 Never

[Bill Ackman @BillAckman]

In a previous post which can be found below, I described how Lucy was left nearly completely blind in both eyes as a result of a large left frontal hemorrhage in February. The hemorrhage caused downward herniation, putting bilateral pressure on her optic nerves along with prolonged (~18 hours) elevated intracranial pressure. A hard fall on the right side of her face at the time of injury likely created a traumatic optic neuropathy in her right eye.

In response to my post, we received incredible support from the X community including some interesting ideas on how to help Lucy. To that end, I thought to make a more targeted outreach to the community for any advice, ideas or input from experts in the eye, optic nerve, and brain or otherwise who can help her recover her vision, which remains her most challenging limitation both physically and emotionally.

Below, I provide some background on her vision and treatment to date. We are incredibly grateful for any ideas you may have. Our goal is to help Lucy and others who have suffered a similar fate by crowdsourcing ideas from the X community.

Background

Initially, both of Lucy’s pupils were maximally dilated and unreactive to light. Slight light reactivity came back to both eyes in the weeks after the hemorrhage. Initially, she appeared to be able to perceive light in the left eye but not the right. The slight right eye pupillary reactivity decreased to zero approximately six weeks after the injury.

Because of the severity of her vision loss and the absence of any other viable therapy, we received emergency FDA authorization in May, three months after the injury, to attempt a novel treatment: injection of Lucy's own mitochondria into her eyes. Details of the procedure and the decision-making that led to our decision to do this therapy are described in a preprint manuscript linked here:

https://t.co/k7cQZgAGdS

The principal rationale for the use of mitochondrial injection was based on her imaging. Optical coherence tomography showed that Lucy's outer retina and photoreceptors were fully intact. The damage was confined to her optic nerves and inner retinal neurons that process visual signals and carry them to the brain. The goal, therefore, was to rescue and enhance the function of her neuronal tissue as much as possible. Animal studies have shown that mitochondria delivered intravitreally cross the inner limiting membrane and are taken up by retinal cells.

After careful research into the potential benefits and risks which we believed, after careful analysis, to be low, we chose intravitreal injection in an attempt to place mitochondria directly on the surface of her retinal neurons.

Within two days of her injections, Lucy’s pupillary responses improved in both eyes. Importantly, she experienced no inflammation or infection. Visual evoked potentials measured weeks later improved, indicating stronger signal transmission from her retina to her visual cortex.

After the procedure, Lucy began reacting to pupillometer and visual examinations when previously they did not disturb her. Because Lucy cannot yet describe precisely what she sees, her increased reaction was itself an important indicator of change. Pupillary responses decreased after a few weeks but remained above pre-injection levels.

Given the success and the limitations of this strategy (among them: sourcing mitochondria from muscle biopsy is not a great long-term solution), we are exploring other ways to isolate and administer Lucy's autologous mitochondria, which we are now isolating from autologous stem cells derived from fibroblasts, a process that takes six or so weeks and requires significant management of the cell culture.

While transplanted mitochondria may improve the function of existing neurons and supporting cells, they are unlikely to result in optic nerve regeneration. Lucy's retinal ganglion cells have already suffered severe atrophy, so even in the best case this strategy has limitations.

In the last two weeks, Lucy's daily visual rehabilitation has begun to produce significant results. She can now reliably track objects both horizontally and vertically when before she could not. At first the objects presented to her had to be illuminated to be seen. More recently, she can track projected images and unilluminated objects.

Lucy is far from having functional vision so we are very open to ideas and potential solutions.

We welcome ideas posted here on X as well as emails to [email protected].

Thank you!

[Tainla Jamir @tainla_jamir]

@BillAckman Praying for Lucy 🙏🫂