Iza-Bren is very effective (not only in TNBC) but its profile is also very chemo-like.
What’s the targeted contribution vs non-specific uptake? Iza-Bren half-life is ~1 day!
What’s the correlation with EGFR expression? HER3 expression? Co-expression of both EGFR and HER3?
A study in Nature reveals that tumour microenvironments can be decomposed into spatially organized multicellular ecosystems that can be accessed non-invasively via liquid biopsy and used to profile individual cancers and target treatments. https://t.co/3ajlUIxq1B
If you're serious about AI engineering (in 2026), then learn these 13 concepts:
1 How Vector Database Works
→ https://t.co/FVxan8xHH3
2 How RAG Works
→ https://t.co/cGmunPTUlb
3 Design Personal Chat Assistant
→ https://t.co/nNWq3onTnW
4 LLM Concepts - A Deep Dive
→ https://t.co/5lCKxq2g4N
5 How to Design an AI Agent
→ https://t.co/JvnPd9773A
6 What is Reinforcement Learning
→ https://t.co/AVpl9j1oit
7 LLM Evals 101
→ https://t.co/nv3Ol8W53p
8 Context Engineering 101
→ https://t.co/OMkiZhkODL
9 AI Coding Workflow 101
→ https://t.co/paIf9ksIU9
10 Agentic Patterns, Simply Explained
→ https://t.co/8YdBBWvTj1
11 How AI Agents Work
→ https://t.co/tk3zkCjRvg
12 Multi-Agent Architectures, Clearly Explained
→ https://t.co/rS5QQS7Jln
13 How MCP Works
→ https://t.co/wgf8gHnnkn
What else should make this list?
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💾 Save now & repost to help others learn AI engineering.
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🫁 MTAP deletions in NSCLC and EGFR.
MTAP del in 10% (n=4926). In stage IV, 83% co-occurred with drivers; EGFR in 48%.
Shorter time to osimertinib discontinuation (19.0 vs 24.9 mo; HR 1.8; p=0.01). No significant OS difference.
Acquired MTAP del at resistance in 13%. Signal of activity with PRMT5 inhibition (BMS-986504).
📖 @JTOonline
DOI 👉🏻 https://t.co/4LuC6kjlur
#CánCare #NSCLC #EGFR #biomarkers #targetedtherapy #lcsm
Claude can now teach your kids any school subject like a $100/hour private tutor from Khan Academy. For free.
Here are 12 prompts that explain math, science, history, and English at any grade level in minutes:
(Save this before it disappears)
What a time to be alive when I have to choose between attending Brian Wolpin’s talk on Daraxonrasib + chemo in 1st line #PancreaticCancer OR @RevMedicines talk on their preclinical asset RM-055 that overcomes KRAS inhibitor resistance, BOTH at the exact same time!
#AACR26
More than 430 abstracts on ADCs at #AACR26!
⬆️ Largely dominated by TOPO1i ADCs and bispecific ADCs
↗️ Dual payload ADCs are growing (36 abstracts)
↘️ Degrader Antibody Conjugates (DACs) not so much (12 abstracts)
⬇️ Limited novel ADC payload classes (<15 abstracts)
This 2 hour Stanford lecture shows exactly how Stanford trains it's engineers to build AI systems. It's more practical than every Claude tutorial & prompting threads you've seen.
Bookmark & give it 2 hours, no matter what. It'll be the most productive thing you do this weekend.
Claude Chat vs Cowork vs Code Tab vs Code CLI — what's actually different?
I used Claude Code to fact-checked every feature against official Anthropic docs and put together this comparison table.
BREAKING: AI can now analyze any stock like a Wall Street analyst (for free).
Here are 10 insane Claude prompts that replace $2,000/month Bloomberg terminals (Save for later)
Wow! Cool--> #PrecisionMedicine in action 👉Individualized mRNA vaccines evoke durable T cell immunity in adjuvant Triple-negative breast cancer #TNBC @@Nature@OncoAlert
👉Individualized neoantigen mRNA vaccine in 14 patients with TNBC following surgery and after neoadjuvant or adjuvant therapy
👉11/14 patients remained relapse-free for up to six years post-vaccination.
https://t.co/tLOTIBVQs3
🚨BREAKING: Claude is insane for market research.
I reverse-engineered how top consultants at McKinsey, Goldman Sachs, & JP Morgan use it.
The difference is night and day.
Here are 12 insane Claude Opus 4.6 prompts they don't want you to know (Save for later)
Important information to keep in mind.
AI is an incredible tool to supplement your work but don’t use it as a substitute for thinking for yourself .. or you atrophy the parts of your brain used for thinking for yourself.
Tumors resistant to one ADC can regain sensitivity to another ADC with a different payload.
Our work shows payload choice—not just target expression—may extend clinical benefit in breast cancer. No evidence that sequential of FDA approved drugs are beneficial in the clinical setting.
https://t.co/WOquXHML7i