We know that aspirin can often be safely discontinued after PCI, provided it is not stopped too early. But how early is too early?
In this meta-analysis of 11 RCTs including 37,443 PCI patients—now incorporating the recent NEOMINDSET and TARGET-FIRST trials—we found that aspirin discontinuation at either ≤3 months or ≤1 month, followed by P2Y12 inhibitor monotherapy, reduced bleeding without increasing MACE compared with 12-month DAPT.
The key finding is that while discontinuation within the first month may provide an additional bleeding benefit, it appears to come at the cost of increased stent thrombosis, particularly in patients at higher ischaemic risk.
https://t.co/83VoBaFuiS
Interventional cardiologists—this one is for you!
The latest focus issue on coronary interventions from @JACCJournals is now live, bringing together key studies and perspectives shaping contemporary practice in interventional cardiology.
From evolving techniques to outcome-driven research, this issue highlights where the field is heading.
Explore the full issue here:
https://t.co/4WDpldtGAn
A selection of original research from this issue:
🫀 The DKCRUSH VIII Randomized Clinical Trial
https://t.co/jHZu7i5yYD
🫀 Intravascular Imaging to Guide Percutaneous Coronary Intervention: Optimize Today for Lasting Outcomes Tomorrow
https://t.co/9PATpstpCa
🫀 Angiographic Surrogate End Points in Drug-Eluting Stent Trials Revisited
https://t.co/q2fbHN1emB
🫀 Immediate vs Delayed Coronary Angiography After Cardiac Arrest Without ST-Segment Elevation: 5-Year Outcomes From the COACT Randomized Trial
https://t.co/xMCBjjdZdt
🫀 Drug-Coated Balloons vs Drug-Eluting Stents for Small-Vessel Coronary Artery Disease
https://t.co/gBlgd6Kk4M
🫀 Aligning Coronary Stent Trial Enrollment With the U.S. Intended-Use Population
https://t.co/oufKMN9vBh
Stay tuned for highlights and key takeaways from our Digital Media Content Creaters!
🚨🇬🇧 BREAKING: British surgeon gives HORRIFYING testimony to the UK Parliament.
He describes how IDF drones arrive right after airstrikes in Gaza, targeting and shooting the injured, including children, right on the spot.
Repost this. Please I beg you
What message does attacking hospitals, pharmaceutical companies and the Pasteur Institute as a medical research center in Iran convey? As a specialist physician, I urge WHO, the Red Cross, Doctors Without Borders and physicians worldwide to respond to this crime against humanity
@MohsinnaqviC42 The real Issue is to Use Public Transport (& make it such that it is usable for the most). Private Cars Should be Banned in Govt. Offices, Esp in Secretariat, Ministries, High Officials { at least as long as Middle easy tension continues, preferably should be the new Norm}
CNN reports Israel is dropping massive bombs directly on residential buildings in eastern Tehran. The blasts are so powerful they are leveling entire apartment blocks and severely damaging surrounding civilian neighborhoods. Absolute war crimes.
Since the declaration of a ceasefire in the Gaza Strip on October 10, 2025, Israel has violated the agreement with near-daily attacks, killing hundreds of Palestinians.
We track Israeli ceasefire violations to date https://t.co/jjnDndNnaK
As we focus on Iran and Lebanon, let's not forget what’s happening in the West Bank.
In one year, more than 36,000 Palestinians were forcibly displaced and 240 were killed. There were over 1,700 attacks by Israeli settlers.
We must end U.S. military aid to Netanyahu.
@Keir_Starmer Did you condemn when Iran's Energy Infrastructure was Bombed? Why were you silent when Isr/USA bombed Girls School in Iran Killing 400+ Innocent, Girls and Their Parents ? Why You didn't condemn when the USA/Isra Started an Illegal War. You don't deserve to be UK Prime Minister
BREAKING: More than 200 children have been killed in US-Israeli attacks on Iran since February 28, according to Iran's Health Ministry
🔴 LIVE updates: https://t.co/sBeD3qRLI0
Israel is destroying branches of a financial institution that serves as a lifeline for thousands of people in desperate need. These attacks are unlawful and must be investigated as war crimes.
https://t.co/xAPhUTLJeW
Talking to leaders of Russia and Pakistan, I reaffirmed Iran’s commitment to peace in the region. The only way to end this war—ignited by the Zionist regime & US—is recognizing Iran’s legitimate rights, payment of reparations, and firm int'l guarantees against future aggression.