Research Faculty @UofLMedicine focussed on environmental medicine. Former healthcare entrepreneur and public sector champion @OPI2Lou and @ONC_HealthIT
Fertilization is not random, and the fastest sperm does not always win: in reality, the egg decides who succeeds.
While for decades we were taught that fertilization is a race won by the fastest sperm, a study published in Proceedings of the Royal Society B shows how human reproduction actually works.
Scientists analyzed follicular fluid from 60 couples undergoing fertility treatment at St Mary's Hospital in Manchester, UK. They discovered that the egg releases chemical signals (chemoattractants) that actively attract sperm from certain men over others.
Through these chemical signals, the egg exerts its own biological selection, influencing which sperm manage to get close. The egg appears to favor sperm that offer optimal genetic compatibility with its own genome — particularly in genes related to the immune system — which may help produce healthier offspring.
Interestingly, this cellular preference does not always align with the couple’s conscious partner choice. In many cases, eggs showed stronger attraction to sperm from non-partner males.
This chemical communication demonstrates that female biology continues to evaluate and select options even after intercourse. Understanding this process could lead to more precise solutions for unexplained infertility. Science continues to reveal the remarkable level of biological interaction that occurs during reproduction.
[Fitzpatrick, J. L. et al. (2020). Chemical signals from eggs facilitate cryptic female choice in humans. Proceedings of the Royal Society B, 287(1928), 20200805. DOI: 10.1098/rspb.2020.0805]
Happy Fathers Day. Remember, we’re all just passing through. All your stuff will be gone, sold or given away. Your children are your heritage. Be a father they can be proud of. 🇺🇸
We need a more modest sales and business development culture in healthcare.
Over time, we’ve normalized behaviors that would feel out of place in almost any other mission-driven sector: lavish conferences, big ticket sponsorships, and a sales ethos that is about everything except the people we serve.
This didn’t happen overnight. It emerged slowly—through competitive escalation, misplaced beliefs about “what it takes to win,” and a creeping assumption that these costs are simply the price of admission in healthcare.
They’re not.
Every dollar spent sustaining excess is a dollar not spent on care, our workforce, or on lowering costs for patients and purchasers.
And in a moment when the system is under real financial strain, continuing to defend this culture should make us uncomfortable.
In my latest Forbes column, I trace how we got here—and why it’s time to reset expectations around what responsible growth and business development culture should look like in healthcare.
https://t.co/1b0Ju5VlWf
A class action case over odor emissions from the JBS pork plant is nearing a settlement.
More than 100 odor complaints in 2025 mentioned JBS directly, records show, and dozens more described smells associated with the slaughterhouse. See the data here:
https://t.co/5bWVENYnF2
Unpopular opinion o' the day:
Muscle mass becomes very unhealthy when it exceeds your cardiovascular system's ability to support it.
This leads to:
* High sympathetic tone
* Increased reliance on sugar burning
* Sleep problems
* Increased Blood Pressure
* Increases in heart & arterial "stiffness"
You don't want more muscle, you want Aerobic Muscle