Not bad, in a Captain Hydra way a time travelling Lyssa Drak made John's parents induct him into fear so he became the first proper supervillain of this universe-... wha-?.. what do you mean that wasn't the intention??...
Change it to - "We translated some passages from a book" Boom!! Evil dead movie
Change it to - "We defrosted a sample from antartica" Boom!! The Thing movie
Change it to - "Something went wrong with the STEM system" Boom!! Evil Within movie
I think the movie has basically nothing to do with Resident Evil that if you change just one line in the whole film and nothing else you can get almost any horror movie you want. When the "Umbrella" scientist said: "we were doing some experiments-, shut up..."