@landau_lab Heartfelt congratulations on your well-deserved promotion to full professor! It's truly an honor to know and work alongside someone as talented and driven as you. Once again, congratulations, and thank you for being such a profound influence in my life!
(1/2) Great paper by #GetzLabAlum Michael S Lawrence’s group! @RemiBuisson and colleagues determined one mechanism underlying #PassengerHotspot generation in cancer involving an effect of #APOBEC3A on cytosine-rich #DNAHairpin structures. https://t.co/iquqgLKHni
Today in @nature: Multi-omics method Genotyping of Transcriptomes (GoT), collab. supervised by @landau_lab of @nygenome/@WeillCornell & @nygctech’s @psmibert. Learn how GoT further dissects #cancer complexity, why 1st co-authors' fingerprints in study art: https://t.co/paTHoBjJbl
Excited to share our single-cell multi-omics work @nature! GoT links somatic mutations to single-cell RNAseq with @10xGenomics scale.
Congrats @AnnaEnim@thinktank_Q @ChaligneRonan and big thanks to many friends & for @psmibert magic!
https://t.co/DgwzLg2ipZ
Not only are we all somatic mosaics, but we are chock full of mutated clones (especially with aging)
Analysis of ~500 people in 29 "healthy" tissues w/ RNA-seq
https://t.co/PnDWM8W31J @sciencemagazine@getz_lab@broadinstitute and collaborators
How do mutant clones gain selective advantage over other cells? With surprising frequency, their "secret sauce" involves inherited alleles. (1/3) https://t.co/i7CLt4xZvK
A (brief) tweetorial (@CharlesSwanton request) for our latest work - Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia https://t.co/PWGIHH0BVD
Excited to share our latest! Single-cell multi-omics uses DNA methylation to infer lineage histories in human leukemias, and intersect trees with DNA mutations and transcriptional identities. https://t.co/I6uOMSGEE4
Congrats @fgaiti @ChaligneRonan; huge thanks to many friends!
Excited to share our newest work on the study of epigenetic diversification in cancer evolution: https://t.co/yVCEwodPqh
With @AbdelWahablab and many friends.