TILs Working Group

We are interested in the immune infiltrate in Breast cancer and what it means for treatment and prevention.

[TILs Working Group @TILsWorkGroup]

We've recently launched a global survey on the potential use of #TILs for future trial designs and use in daily practice. We would love to hear what you have to say 👇https://t.co/RaEvMXuSYb

[Abi Siva MD @AbiSivaMD]

Such a privilege to be part of the international TIL Working Group @TILsWorkGroup and to collaborate with Dr. Salgado on NeoTIL. #SABCS @muschollings @stolaney1 @OncBrothers @LoiSher

[Sherene Loi, MD @LoiSher]

@TILsWorkGroup moves into our AI era
#sabcs2025
#tils @OncoAlert

[Ilana Schlam @IlanaSchlam]

Amazing presentation by Roberto Salgado from @TILsWorkGroup

TIL assessment of APHINITY using CASE45 AI model and manual TILs (great ICC)

Combining AI and manual assessment is a better prognostic biomarker than either one of them

[Maria Vittoria Dieci @vitti10]

TILs matter in HER2+ BC!

In ShortHER trial, mapping their spatial organization with AI assessing:
🔹Immune-tumor interaction
🔹Aggregates/TLS (Hotspots)
further refines prognosis beyond manual evaluation

PS2-08-11 at #Sabcs25 @UniPadova @iov_irccs @TILsWorkGroup

[Jose Fernando Moura, PhD @FernandoOnco]

Tagging @TILsWorkGroup to amplify this great work

[Sherene Loi, MD @LoiSher]

✨✨hot off the press from the #loilab. We show here that pregnancy & breastfeeding is associated with increased T cells in the normal breast and protection against #tnbc #breastcancer moving the role of immunity from treatment to prevention.
👏👏Thanks to @FAndreMD @DrChoueiri @MyriamChalabi for the opportunity to present #ESMO25 @OncoAlert @myESMO

@PeterMacRes @PeterMacCC @UniMelb

thanks to our funders @BCRFcure @TheMarkFdn @NBCFAus

@Nature Article is here: https://t.co/pu3STvXvm1

[TILs Working Group @TILsWorkGroup]

The EU-funded MSCA Doctoral Network “Spatial Crosstalk in Immune-Oncology” (SpaXio) is now officially recruiting 14 PhD students to decipher the metastasis-promoting microenvironment of colon and breast cancer. More info here: https://t.co/buWAiRPFgV

[Sherene Loi, MD @LoiSher]

😎if #TIL had been the prespecified biomarker, pembrolizumab might well be approved for this indication. PD-L1 IHC has real technical limitations- patients deserve multiple validated ways to identified immune enriched tumors. #TILs are simple, free & readily available- wait 🤔is that the problem? @oncoalert @TILsWorkGroup #bcsm

[TILs Working Group @TILsWorkGroup]

Study across 45 institutions shows AI validity in TIL quantification for melanoma. Reproducible with prognostic validity and open-source. @tznaung 👉 https://t.co/CprLGJYH80
#AIinPathology #Melanoma #ComputationalPathology

[Jose Fernando Moura, PhD @FernandoOnco]

Some studies shows how we can reduce costs based on biomarkers
SHORT-HER 9 weeks of trastuzumab is ✅ based TILS 20% or more
@TILsWorkGroup @OncoAlert #oncoalertAF @JAMAOnc⤵️
https://t.co/VlXgw6Iohh

[TILs Working Group @TILsWorkGroup]

📄 Pitfalls in ML-based TIL assessment
🔗 https://t.co/qpf9qZ1zbt
📄 Spatial analyses of immune infiltration in cancer
🔗 https://t.co/8HlHlVhla9

#ImmunoOncology #DigitalPathology #TILs

[TILs Working Group @TILsWorkGroup]

🎉 Thrilled to share that 2 @JPathol papers from the TILs Working Group ranked in the Top 10% most-viewed in 2023!
👏 Huge thanks to all collaborators, @JPathol & our readers for your support.
📎 Links in comments ⬇️
#TopViewedArticle #TILsinBreastCancer #pathology

[Erika Hamilton, MD, FASCO @ErikaHamilton9]

Great slide highlighting not only are TILs predictive of pCR...it also translates to being prognostic beyond pCR for good outcome and DFS.

Seems like we have a LOT of data on TILs now, why aren't they standardly provided on path reports???🧐

#SABCS24
@SABCSSanAntonio
@OncoAlert

[TILs Working Group @TILsWorkGroup]

Celebrating 10yrs of #til in #BreastCancer #sabcs24

[TILs Working Group @TILsWorkGroup]

🤩🍾10th anniversary TILs-Working Group at @SABCSSanAntonio 2024 - everyone welcome! RSVP here: https://t.co/xMkVqwGYr7

[TILs Working Group @TILsWorkGroup]

The largest TILs-Workshop done so far! More than 100 pathologist, residents in training and medical students learning how to score TILs. Organized by the Narayana Medical College, India. Who follows? 💪🏼

[TILs Working Group @TILsWorkGroup]

@LoiSher

[TILs Working Group @TILsWorkGroup]

Join us for the 2024 Peter Mac Breast Cancer Medical Oncology Education Day! 📅 On Friday, 11th October, dive into the latest in breast cancer care with experts at Peter Mac or via Zoom. Registrations: https://t.co/3OihTUlqSt @PeterMacRes @PeterMacCC

[TILs Working Group @TILsWorkGroup]

🤩Check out latest article in @NatureRevCancer! #TILsInBreastCancer #Researchpaper

[Nature Reviews Cancer @NatureRevCancer]

Towards targeting the breast cancer immune microenvironment https://t.co/GHXVLpHfA9

[Sherene Loi, MD @LoiSher]

Our latest review is out now on targeting #BreastCancer #Immunity #tme #trm #CancerResearch many thanks to @NatureRevCancer

@PeterMacCC @PeterMacRes @TILsWorkGroup