grape king

writer of short stories & long essays, hater of (redacted). just trying to make it in this bitch of a life • AuDHD • hEDS • LC

[grape king @titdance]

i was 24 working on my portfolio to apply to grad school when C19 disabled me and triggered the symptomatic phase of a genetic disorder. i’ve lost friends, family, my writing community, and my capacity to work a normal job. at times i can’t use my arms or walk/stand well.

[Jack | amatica health @JackHadfield14]

COVID is the main driver in the increase of unemployment.

I was 21, starting my career in aerospace engineering, when I was infected by COVID-19 - that ended immediately.

I am now 25 and still unable to work a normal job. I am 1 in millions with this exact story.

[Harry Spoelstra @HarrySpoelstra]

Beyond brain fog: viral proteins as convergent drivers of neuroinflammation and proteinopathy

🚨“COVID-19 never really leaves your brain.”

New science review proposes SARSCoV2 viral proteins stay behind as long-lived toxins, triggering chronic neuroinflammation and planting the seeds of Alzheimer’s and Parkinson’s, even after mild infection.

This very interesting and eye-catching GERMAN review reframes post-viral neurological syndromes( L0ngC0vid) as driven by persistent viral proteins acting as long-term toxins ("protein-as-pathogen" model), not just the active infection!

➡️Core mechanisms:
- SARSCoV2 Spike and OTHER viral proteins activate glial TLR4/TLR2 receptors, triggering chronic neuroinflammatory cascades via NLRP3 inflammasome,
- They also disrupt autophagy, allowing toxic protein aggregates (tau, amyloid-beta, α-synuclein) to accumulate and seed neurodegeneration,

➡️SARSCoV2 specific evidence:
- Animal studies show Spike protein alone (without live virus) induces TLR4-mediated cognitive deficits, memory impairment, synaptic loss, and sustained neuroinflammation, recapitulating post-COVID syndrome,
- Spike binds α-synuclein, accelerating Parkinson-like clumps,

➡️Human data evidence:
- Millions experience "brain fog,"
- Post-COVID patients exhibit measurable brain damage: cortical thinning, hippocampal iron accumulation, and biomarkers of ongoing neuronal injury,

➡️Broader risks:
- Even mild infections leave lingering proteins that promote Alzheimer’s and Parkinson’s-like pathology via shared pathways,
- Same pathways seen in influenza, dengue, West Nile etc,
- Mild infection = no protection,

‼️So, according to this review, the “protein-as-pathogen” model makes it crystal clear: every new SARSCoV2 infection (even mild or asymptomatic) deposits more of these long-lived toxic viral proteins into the brain. They don’t fully clear. They accumulate.

Each reinfection reloads the TLR4/TLR2 → NLRP3 inflammasome trigger and further collapses autophagy, speeding up the tau/amyloid/α-synuclein proteinopathy and neurodegeneration.

SARS-CoV-2 does not just infect.

It weaponizes its own proteins as long-lived intracellular saboteurs.

Millions are probably already carrying this hidden payload.

This is not brain fog.

This is a silent, population-scale reprogramming of human brains toward dementia-like decline.

The long-term neurological cost will probably dwarf the acute pandemic itself!
#AvoidSars2 #AvoidReinfections
https://t.co/x0oxacaNwl

[Laura Miers @LauraMiers]

@JamesThrot @DawnAllsun I think it was 2021 when I realized we were all going to go through some things, & no one was going to listen, & there would be no way to stop it.

[James Throt MBBS, MD, PhD, FRCPath @JamesThrot]

What am I seeing?

- Reduced empathy
- Increased aggression
- Rising support for authoritarianism
- Declining critical thinking
- Less moral inhibition
- Rising disinhibition & antisocial behavior
- Lack of focus/commitment
- Frequent memory lapses
- Increased impulsivity

[Conor Browne @brownecfm]

1. Remember that any attempt to paint Long Covid as psychogenic in nature deliberately and completely incorrectly biologically decouples SARS-CoV-2 infection from Long Covid. In essence, this rhetoric shifts the causative factor for LC from the virus to the patient's mind.

[James Throt MBBS, MD, PhD, FRCPath @JamesThrot]

As a neurologist, it is now patently clear to me that the vast majority of people on the planet are suffering from neuroinflammation or brain damage (likely both)

The way people speak & behave has changed. Markedly so.

Whether irl, or via messaging/social media. It’s noticeable

[Samira Hosam @Vibeka]

If you can't donate as charity for my father's soul, please help us with a meal to ease our hunger. We are going through very hard days, and even a small contribution can make a real difference for my family today 😭💔🙏https://t.co/Pqi4iyecWl

[yousef In Gaza🇵🇸 @yousefHame64303]

Pain has become a daily part of my life, and I depend on painkillers to get through the day. With my current circumstances, covering these basic needs has become difficult.
Any support would be greatly appreciated. Thank you.
https://t.co/PnlleBk8XB

[Salah_Gaza🇵🇸🍉 @Salah_Gaza18]

This is me.

Most people only see the posts I share, but they do not see the weight I carry every day.

I am a father trying to protect his child. A brother trying to care for Mustafa, who suffers from cerebral palsy and severe muscle atrophy. A student still fighting to complete his education despite everything that has happened.

Some days I feel strong. Other days I feel exhausted and overwhelmed. But I keep going because my family depends on me.

I am not looking for sympathy. I am simply asking you not to forget us.

Please keep Mustafa and my family in your thoughts, and if you can, help us share our story. ❤️🙏🇵🇸

#GazaGenocide‌ #FREEPALESTİNE #Palestine #GazaİçinSesÇıkar

@academic_la @ireallyhateyou @DrNeenaJha @indianloonie @ISASaxonists @ihcentoo @AnfieIdFix @umaymohamed @IWantToBeSam2 @anarchotadigism @kvwesley_ @KhawajaMAsif @9mmScorpion @cleradinsm @sydneyimpact @iwasnevrhere_ @lukeisamazing @cherryfunked @mikerecine @squared_nation @Louis_Allday @digermesele @enoughformethx @sistertonin @flackospalace @mrs_socialista @tnega74 @sale_gose @burak_turna @ThatTimWalker @KatanaSpeaks @obaa_boni @Frances_Coppola @soulkhan @meralhece @olivelacedpen @Terrilltf @ainiladra @mothDOOMtongue @WarFrontIntel
@lsthart @AlexSamTG @atulysharma @quelespaso @andrewtanyongyi @ArcticMangoes @AyshaSusmaz @sawaya_nicolas @CaronAymericoff @LaurenH10706635

[Cat (CovidSolidarity) @CovidSolidarit1]

They told people kids don’t get Covid. They told people kids don’t get Long Covid. People went back to “normal” telling themselves it was “for the sake of the kids”.

This is where we’re at.

[Harriet Carroll: Long Covid Scientific Consultancy @angryhacademic]

By playing the psyche card, he is inferring that our minds are separate from the physical world (we are all made of atoms, fundamentally). Thats quite an extraordinary claim in itself, let alone when used to tell sick people they need to think themselves better

[Harriet Carroll: Long Covid Scientific Consultancy @angryhacademic]

Plus the myriad of factors that we havent worked out yet - like central B12 deficiency which is only recently starting to be properly recognised in research (not yet in clinical practice), despite evidence im aware of from at least the 1990s

[Harriet Carroll: Long Covid Scientific Consultancy @angryhacademic]

Infers fatigue and chronic pain have no known organic cause.

Which is true, if you ignore small fibre neuropathy, autoimmunity, neuroinflammation, dysmetabolism, nutrient deficiencies, endocrine problems, mast cell activation (etc)... Most of which are not properly tested for

[Harriet Carroll: Long Covid Scientific Consultancy @angryhacademic]

Apparently post-war functional paralysis has no known structural cause so the ONLY other possibility is a functional cause.

Couldnt possibly be that weve not worked out the right tests yet!

[Harriet Carroll: Long Covid Scientific Consultancy @angryhacademic]

This is absurd. He gives the example of an athlete breaking their finger during a game and not realising until the end. Apparently there's no biological reason for this 🧐🧐🧐

*Whispers* adrenaline

[Free Rodney Hinton 🇸🇳 @onlineva_]

there's a new bathroom in downtown, but to use it you have to have a phone so they can send you a OTC. the perfect enmeshment of anti homeless infrastructure and surveillance.

anyway everyone read smooth cities.

[Prem Thakker @prem_thakker]

A US group founded to “enhance Israel’s image” & staffed by ex-Israeli officials (including Netanyahu’s negotiator who got US to send $3.8B per year to Israel) is revealed to have helped blueprint the new Republican push to fuse the Israeli & US militaries.https://t.co/t0lJM3FeaW

[Prof. Stefan Rahmstorf 🌏 🦣 @rahmstorf]

I'm afraid that this is why the US administration wants to shut down ocean observations: they don't want the people to know what is happening in our oceans, as it does not fit their ideology and the interests of their fossil fuel industry funders.

https://t.co/G1E5zXdyid

[tern @1goodtern]

"If you stop testing it will go away"

I do find it weird that climate activists fell for this when it was done with Covid.

[Olive 🌿 @oliveegirl]

"Few people were later found dead amongst the ruins. Some of the corpses were disposed as garbage, thrown out with rest of the rubble."

[t a z z i @CurlyTazzi]

The sadness in his eyes is soul crushing. Children should never have to suffer or pay the price for the greed of murderous politicians.