Tornike Mamuladze

[Ruchita Kothari @RuchitaKothari_]

Very excited to share our work in @CellCellPress. Here, we propose that meningeal mast cells regulate brain inflammation after stroke by coordinating immune infiltration from the skull bone marrow, through the meninges, and into the brain!

https://t.co/km7u0AhrJN

[Tornike Mamuladze @tmamuladze]

Finally, this work was a true team effort. Immense thanks to my brilliant co-authors, to @jonykipnis for his invaluable mentorship, to the entire @kipnislab at @WUSTLmed, @felipe_pinh0 @TiagoZaninelli Mike Diamond @WUSTL Xinzhong Dong @JohnsHopkins for their support.

[Tornike Mamuladze @tmamuladze]

I'm excited to share our new study published in Cell.
This work uncovers a critical role for dural mast cells in shaping cerebrospinal fluid flow and protecting the brain from infection. https://t.co/a8k9Qny1yc

[Jonathan Kipnis 🟦 @jonykipnis]

Excited to share this new work from our lab, led by an exceptional graduate student, Tornike Mamuladze (@tornikemamu), on the role of meningeal mast cells in regulation of brain/dura access points, with implications to CSF flow dynamics and meningitis ||
https://t.co/DXnOZ8TZhb

[Tornike Mamuladze @tmamuladze]

This mechanism serves as a frontline defense against CNS infection. Pathogens such as S. agalactiae and S. pneumoniae exploit ACE points to access the brain. Mast cell activation redirects CSF flow and recruits neutrophils, limiting this bacterial invasion.

[Tornike Mamuladze @tmamuladze]

@StateDeptSpox Don't leave Georgian people with Russia! US should take a definitive actions and sanction Georgian government!

[State Department Spokesperson 2013-2025 @statedeptspox_a]

Georgian Dream’s decision to suspend EU accession is a betrayal of the Georgian constitution. We condemn excessive force used against Georgians exercising their freedom to protest and have suspended our Strategic Partnership with Georgia.

[Jonathan Kipnis 🟦 @jonykipnis]

Just watched a wonderful Guillermo del Toro's Pinocchio film! Beautiful and masterful!
"Lies, my dear boy, are found out immediately because they are like long noses, visible to all but the teller of the lie." Geppetto

[Jonathan Kipnis 🟦 @jonykipnis]

Very excited to share a new story from @kipnislab led by @Drieu_Antoine in collaboration with many others from within&outside our lab on parenchymal border macrophages (PBMs) in regulation of CSF flow with implications to aging and Alzheimer's disease || https://t.co/CbBWljpT2D

[Jonathan Kipnis 🟦 @jonykipnis]

I’m humbled and honored beyond words! Thank you @theNAMedicine and everyone who supported me!

[WashU Medicine Pathology & Immunology @washu_pathology]

Exciting! #NIH awarded Marco Colonna, @jonykipnis @GwenRandolph_ with @WashUNeurology @holtzman4 $15M for Alzheimer’s research. Focus is on myeloid cells including microglia & macrophages & lymphatics in Alzheimer’s disease & Cerebral amyloid angiopathy. https://t.co/bEv8O8gyJW

[Eto Buziashvili @EtoBuziashvili]

On this day in 2008, when I was doing groceries, Russia invaded Georgia. As the news on Georgian radio were nervously reporting about Russia’s bombing and killing civilians, I was already running to my parents’, with the only thought to see them. 1/9

[Jonathan Kipnis 🟦 @jonykipnis]

When we stated working on meninges ~15 years ago, nobody cared about "the borders"... over the years "the borders" of the brain have taken the central stage of neuroimmunology! "From esoteric mainstream" could have been an alternative title of this feature https://t.co/mKYxbzKRJw

[WUSTL Immunology @WUSTLImmuno]

🥳🥳🥳Congratulations to @WUSTLImmuno's very own Dr. Marco Colonna @TheColonnaLab on his election to @theNASciences! 🎉🎉🎉

[Jose A. Mazzitelli @mazzitelli_j]

@smyth_leon and I are excited to share our latest work @NatureNeuro ! We describe an unexpected form of neuroimmune communication whereby CSF gains direct access to skull bone marrow niches and regulates immune supply to CNS borders. https://t.co/ZoZoOE0GjB

A thread. 👇

[Tornike Mamuladze @tmamuladze]

Слава Україні!

[Dmytro Kuleba @DmytroKuleba]

Putin has just launched a full-scale invasion of Ukraine. Peaceful Ukrainian cities are under strikes. This is a war of aggression. Ukraine will defend itself and will win. The world can and must stop Putin. The time to act is now.

[Global Immunotalks @globalimmuno]

The recorded video of Dr. Jony Kipnis seminar entitled Immunological uniqueness of brain borders is now available at “Global Immunotalks” YouTube Channel https://t.co/DAmIeN0faP
Hope you enjoy it!
#globalimmuno #immunology

[Tornike Mamuladze @tmamuladze]

@jonykipnis Congratulations

[Jonathan Kipnis 🟦 @jonykipnis]

Now officially out… a great effort of ⁦@JasminHerz1⁩ and co-authors on how IL4 regulates memory || GABAergic neuronal IL-4R mediates T cell effect on memory - ScienceDirect https://t.co/1BNguXwYTU

[Kipnis Lab @kipnislab]

Massive congrats to @JSRustenhoven for getting one of the 2021 Rutherford Discovery Fellowships! 👏👏👏