Toby Baker

PhD student in the Cancer Genomics Laboratory at the Francis Crick Institute. Studying the evolutionary trajectories of metastatic cancers.

[Peter Van Loo @VanLooLab]

Tumor samples vary in purity and ploidy, both of which confound DNA methylation measures from bulk sequencing. We developed CAMDAC to clean up this signal. Here's our extended preprint with new insights from applying CAMDAC to TRACERx lung RRBS data: https://t.co/064PgTFt1l

[Maxime Tarabichi @MaxGalder]

Millions of extra mutations retrieved in the non-unique regions of cancer genomes!? In the coding sequence of known cancer genes? In immunoglobulin genes in lymphoid tumours? And members of intriguing gene families?
So thrilled this is finally out:
https://t.co/3zUsWReDsI
🥲🙃

[Lili Larose Cadieux, PhD @DrLaroseCadieux]

CAMDAC: Copy number-Aware Methylation Deconvolution Analysis of Cancer live on GitHub at https://t.co/RnpS1jceSz! Run CAMDAC on tumour RRBS data & get tumour purity, allele-specific copy number and methylation rates free from normal contaminants. Preprint: https://t.co/NHM2uJpjVS

[The Francis Crick Institute @TheCrick]

📰 @VanLooLab, @MaxGalder & the #PCAWG consortium have analysed tumours from over 2,600 patients.

They found lots of genetic diversity in individual tumours, and confirmed that tumour evolution is driven by changes that benefit the cancer. @CellCellPress
https://t.co/fzk7oEn9Z5

[Nicholas Navin @nicholas_navin]

Excited to share our new work published in @nature today by @darlanminussi @VanLooLab @HanghuiYe and Franziska michor on TNBC, in which we asked what happens after the initial burst of chromosome instability? https://t.co/qny1SF1uAP

[Maxime Tarabichi @MaxGalder]

Please join us for an afternoon of virtual talks on the 30th November starting at 12.30pm UK time: Somatic Evolution and Tumour Microenvironment Symposium 2020 https://t.co/RIIo0MVgvH 👌🙂

[The Francis Crick Institute @TheCrick]

📰 By analysing 47 million genetic changes in 2,658 tumours, a team led by our @VanLooLab and @emblebi has found that there can be genetic signs of cancer years earlier than we thought.

��️ @ATJCagan | #pcawg | Read the full story ➡️ https://t.co/0FmkpkrQQs