Tom Greenfield ND

naturopath and osteopath, writer, lecturer, presenter, self-employed, views are not those of my employer. RT = retweet

[Eric Topol @EricTopol]

There hasn't previously been a treatment vs pancreatic cancer this successful. Striking improved (a > doubling) survival results @NEJM and @ASCO today with daraxonrasib, which also became available via an FDA approved early access program and began shipping to physicians this week @RevMedicines
https://t.co/e04jqJMPw0

[A Midwestern Doctor @MidwesternDoc]

This is a recent update from the man with terminal COPD who was able to cure it with nebulized DMSO.

He is mostly recovered now, his doctor admits he's improved, and many others have also reported similar results for asthma, severe COPD, and other "incurable" lung disease.🧵

[Tom Greenfield ND @TomGreenfield]

A systematic overview and second-order meta-analysis of nature-based interventions for stress, anxiety and depression

[Eric Topol @EricTopol]

Nature-based interventions are good for your health. A new systematic assessment (and they are free)
https://t.co/0xoorjvwss

[Eric Topol @EricTopol]

Important #LongCovid finding of auto-antibodies in patients directed to neural tissue, and then, by transferring the antibodies, recapitulated the disease symptoms in mice @CellCellPress @VirusesImmunity @putrinolab
https://t.co/s4bSXjTVe6

[Tom Greenfield ND @TomGreenfield]

Breast cancer (BC) incidence was positively associated with conjugated bile acids, including the novel glycohyocholic acid, and inversely associated with unconjugated bile acids, suggesting a potential role for bile acid conjugation in carcinogenesis. Multiple dietary factors were linked to these metabolites, highlighting potential metabolic pathways connecting diet and BC.
https://t.co/yo0zbCfp4p

[Ian Miles Cheong @ianmiles]

Japan just had the fewest babies born in any year on record. Not since the war. Not since the 1918 flu. Since records began in 1899.

705,809 births, the tenth annual record low in a row, and they're now down 30% in a decade. More than two deaths for every birth. The population shrank by almost 900,000 people in twelve months.

This is what a demographic spiral looks like in real time. Fewer young people now means fewer parents in twenty years, which means fewer births in thirty. Recovery requires reversing a trend that has been running for half a century.

[Tom Greenfield ND @TomGreenfield]

After a a 16-week resistance training programme:
“Resistance training significantly improved muscle strength regardless of diet type, suggesting that a vegan diet did not compromise adaptations to strength training.”

https://t.co/Xnw0LZmSsa

[Tom Greenfield ND @TomGreenfield]

“Emerging evidence suggests that maternal ketogenic diet may significantly influence brain development, maturation and behavior on numerous levels, possibly linking brain abnormalities, microbiota alterations and behavioral deficits.”

https://t.co/fCIo5Ot0zH

[Reiner  @erlesen]

Artificial sweeteners drive divergent gut and genetic responses across generations
https://t.co/tHO1kjdjgS
Can sugar substitutes affect your unborn child? Mouse study links sucralose and stevia to gut and metabolic changes passed across generations
https://t.co/lQOnYOl1jY

[Tom Greenfield ND @TomGreenfield]

The consumption of a diet high in fat and fructose induces sex-specific
alterations in the expression of key genes related to insulin synthesis,
inflammation and apoptosis in the pancreatic beta-cells of rodents.

“females showed lower vulnerability, possibly because of adaptive responses in insulin synthesis signaling influenced by sex hormones.”

https://t.co/L0pLJfadlp

[Tom Greenfield ND @TomGreenfield]

Serum thyroglobulin (Tg) can predict population iodine status categories based on Urine Iodine Concentration (UIC) thresholds. The proposed median Tg cutoffs appear particularly useful for detecting iodine deficiency (higher Tg values) at lower ends of the UIC spectrum.

https://t.co/fNbWD0hCH2

[Tom Greenfield ND @TomGreenfield]

“The present meta-analysis revealed the efficacy of ketogenic diet therapy (KDT) in the treatment of genetic epilepsies, particularly in epilepsies associated with SLC2A1 and SCN1A mutations, but KDT had relatively poor efficacy in epilepsies related to CDKL5 and KCNT1 mutations. Notably, compared to other follow-up intervals, at the 6-month post-KDT follow-up interval patients showed the highest overall responder and seizure-free rates.”

https://t.co/FNId3LvEs4

[Tom Greenfield ND @TomGreenfield]

“current findings underscore the promise of dietary DNMT modulators (e.g., epigallocatechin-3-gallate, curcumin, genistein, resveratrol, sulforaphane, and folate) as foundational elements for precision nutrition strategies aimed at promoting healthy aging and mitigating age-associated disease risk.”

https://t.co/ncE40fJJu3

[Tom Greenfield ND @TomGreenfield]

“This review summarizes mechanistic and clinical evidence on the electrophysiological effects of selected nutrients, food constituents, and supplements-including grapefruit juice, licorice, over-the-counter products, and energy drinks. Gene-nutrient interactions and their impact on ion channel function, drug metabolism, and electrolyte balance are discussed. The second part outlines genotype-specific considerations, such as potassium supplementation and dietary guidance for rare forms of Long QT Syndrome (LQTS), including Andersen-Tawil and Timothy syndromes.”

https://t.co/xf93l7ZENS

[Tom Greenfield ND @TomGreenfield]

“This review synthesizes emerging evidence on both macronutrient and micronutrient influences on serotonin pathways, connecting central and peripheral mechanisms including gut-brain interactions, presenting a new perspective on nutritional targets and translational potential for various serotonin-related diseases spanning mental, metabolic and gastrointestinal outcomes.”

https://t.co/TfiiGW0UBx

[Tom Greenfield ND @TomGreenfield]

“Probiotic and synbiotic supplementation significantly reduces inflammatory cytokines (CRP, IL-6, TNF-α) in individuals with prediabetes and T2DM, with the strongest effects observed in those with higher baseline inflammation and longer intervention durations. These findings underscore the importance of tailoring supplementation strategies to individual inflammation status, intervention duration, and metabolic profile to optimize therapeutic outcomes.”

https://t.co/yEOqIjPbaY

[Tom Greenfield ND @TomGreenfield]

“In this pilot study, Hepatitis C virus (HCV)-cirrhosis presents sex-specific FM differences, suggesting potential microbial signatures. Dietary modifications correlated with microbiota shifts, highlighting the importance of diet-microbiota interactions and the need for targeted dietary interventions to improve patient outcomes.”

https://t.co/nJQI8iCBzb

[Tom Greenfield ND @TomGreenfield]

“Results suggest that a dietary pattern network reflecting the consumption of ultra-processed sweets and snacks is associated with incident CVD in a sample of the French population, independent of diet quality.”

https://t.co/HF2vkr4OY5

[Tom Greenfield ND @TomGreenfield]

“This review mainly discussed the research progress on energy and fat-manipulated diets (caloric restriction diet, ketogenic diet, and high-fat diet) and several nutrients (polyunsaturated fatty acids, phospholipids, copper, iron, zinc, selenium, vitamin A/D/E/C, and some vitamin Bs) in the treatment of Charcot-Marie-Tooth disease (CMT) and related peripheral neuropathies.”

https://t.co/XDBCAZKCQ3