I'm excited to announce that @AmcaInc has raised a $300M Series B at a >$1B valuation, led by @CaffeinatedCap with major support from @LightspeedVP, @a16z, @Lux_Capital, and others.
We're on a mission to reconstitute a supply chain that has too often put profit over country.
Today Boom unveils our first completed supersonic turbine core, a 2GW Superfactory, and—one more thing—the world's most advanced all-digital foundry to cast single crystal turbine blades and vanes https://t.co/q2KpL3dZi2
Στα εγκαίνια της Διακλαδικής Σχολής Μη Επανδρωμένων, αλλά και των Αυτονόμων Συστημάτων Θάλασσας. Ένα περαιτέρω βήμα, που δημιουργεί τεράστιες δυνατότητες για το Πολεμικό Ναυτικό μας στο Αρχιπέλαγος, με τα Αυτόνομα Συστήματα τα οποία μπορούν να προσφέρουν απεριόριστες δυνατότητες στην επιτήρηση και αναγνώριση, στην προστασία των λιμένων, στον ναρκοπόλεμο και στην ασφάλεια των υποδομών.
Αυτό το νέο Πολεμικό Ναυτικό με τις σύγχρονες πλατφόρμες, θα μπορεί να προστατεύει όχι μόνο την κυριαρχία και τα κυριαρχικά δικαιώματα, αλλά και τα ενεργειακά και επικοινωνιακά δίκτυα στον βυθό, τα οποία είναι επίσης απαραίτητα για την ασφάλεια της Πατρίδας.
(από τον χαιρετισμό μου στην τελετή των εγκαινίων του Κέντρου Διακλαδικής Εκπαίδευσης Μη Επανδρωμένων και Αυτόνομων Θαλάσσιων Συστημάτων στο Κέντρο Εκπαίδευσης ΠΑΛΑΣΚΑΣ του ΠΝ)
#HellenicNavy
Let me explain why is @VardaSpace is such an important company
A patient who has cancer has cells that have proteins that are activated leading to growth, replication and then damage.
Targeted drugs work on these cells in 2 ways:
1. Inhibit the receptor (the protein), essentially jamming its function until the drug wears off. An example is Tamoxifen, used in breast cancer to block oestrogen receptor binding.
2. Degrading the receptor altogether so signalling doesn't work and the cell needs to spend time recreating the receptor before it can work again, an example being Fulvestrant which degrades the receptor itself.
The second option here is important to understand because the effect of it significantly out lasts how long the drug lasts in your system. One type of these drugs is called PROTACs - it's a newer type of cancer drug that destroys these proteins (proteolysis) removing functions often related to cancer signalling.
Now these drugs are complex, 15+ chemical steps and can be upto 4x more heavy than normal drugs. With each molecule taking many shapes, when packed together, they often don't form a uniform lattice shape. On Earth, gravity leads to convection currents that feeds these molecules unevenly into the forming crystal, too fast resulting in non-uniform crystal formation.
These drugs:
- Dissolve poorly when ingested
- Have difficulties crossing cell membranes
- Lead to unpredictable bioavailability
- Require high doses in order to get enough drug in the system
Varda here by @WillBruey and @zebulgar aims to solves this with undisturbed crystal formation growth in microgravity.
With a new purer drug you get:
- Predictable bioavailability
- A more stable drug
- A better outcome for patients
This is Varda
We’re 3 for 3 in orbit this October. This time, it’s space drugs. W-7 carries pharmaceutical hardware and a promising new type of cancer medicine known as a protein degrader. Microgravity will help overcome one of its biggest limitations: poor solubility.
Growing fast and looking for hyper-talented people that want to solve hard problems, work on a mission-driven team and change the world together! If that’s you come join the top startup in Austin!
Go @AvenCard 🚀
"My brother Mark’s buddy who was a senior executive at Amazon did a $200,000 aven loan to redo his kitchen and the guy was apparently super impressed with the entire process and the product"
This is the tip of the iceberg for synthetic biology. Our data centers are still primarily powered by biology. Natural gas crimes from biology’s ability to organize matter in a negentropic way. Biology gives us order at very little economic cost. Programming it efficiently will lead to a new Cambrian explosion.