No. That is criminal. You do not bring back Wuhu Island and then treat the Miis like background extras. Wuhu Island belongs to the Miis. That island has Mii DNA in the pavement. The swordplay arena, the cycling roads, and the little resort vibes that is sacred Mii territory.
wow… after years of being told to “just lose weight” and getting body shamed over symptoms tied to insulin resistance, it feels validating to finally see the condition named in a way that actually reflects how debilitating it can be.
hoping this leads to better research lol 😅
In 1935, two American doctors examined seven women's ovaries and saw small lumps. They called them cysts and named the disease after them. They were wrong. It took 91 years to fix.
What we called PCOS is now Polyendocrine Metabolic Ovarian Syndrome (PMOS), announced today in The Lancet by an international panel of doctors and patients. The renaming followed more than a decade of consensus work and 22,000 patient and clinician survey responses.
The lumps Stein and Leventhal saw were never cysts. Modern imaging shows they were follicles, the tiny sacs inside the ovary that grow and release an egg each month, frozen partway through by a hormonal imbalance. PMOS is a multi-system disorder centered in the endocrine system, the body's network of glands that produces hormones like insulin (controls blood sugar), cortisol (the stress hormone), and thyroid hormones (set the body's metabolism). The ovary trouble flows downstream from there.
The naming choice is not academic. When doctors hear "ovary" in a diagnosis, they look at the ovary. "Metabolic" and "endocrine" send them to the whole body.
PMOS affects roughly 1 in 8 women worldwide, more than 170 million people. The WHO estimates 70% have never been diagnosed. Among those who do, 1 in 3 wait more than 2 years, and nearly half see 3 or more doctors first. The CDC reports more than half of women with PMOS develop type 2 diabetes by age 40, a risk 5 to 10 times higher than women without the condition. Around 37% have clinically significant depression, compared with 14% in women without it. Anxiety runs at 42% versus 8.5%.
A label born from a 1935 look at seven ovaries is finally going away. The new diagnostic guidelines roll out fully in 2028. By then, a woman walking into a clinic with these symptoms should hear questions about her blood sugar and her mood alongside her cycle. Those are the parts of the disease the old name hid for 91 years.
Happy RSD friends! We’ll be monitoring over 200 record stores on our Discord tomorrow for when overstock goes up online.
Meanwhile, to celebrate RSD, like and repost this tweet for a chance to win one of two copies of Fortnight 7in from last year’s RSD 🫶🏻
🎶 NKST RSD GIVEAWAY 🎶
Want to win some exclusive Noah Kahan RSD vinyls?!
In honor of Record Store Day, and Noah’s past releases, the Noah Kahan Street Team is giving away:
• A 2024 RSD exclusive I Was / I Am vinyl
• A 2024 RSD exclusive Lacy / Stick Season 7” vinyl