I'm very pro-statins for their incontrovertible benefit vs atherosclerotic buildup and reduction of cardiovascular adverse events. Their benefits greatly overrides the risks.
However, I always keep in mind 2 key side-effects:
1. Inducing Type 2 diabetes, uncommon, but more likely with aggressive dosing of statins. I've written about this concern since 2012 in a @nytimes oped and got a lot of flak for it. Can be missed by clinicians not cued it.
https://t.co/Bd7lZADuY4
2. Myopathy, muscle inflammation, cramps. Not uncommon, hit me after years of taking statins. New paper on the putative mechanism https://t.co/gcnGOEBsGx
More than 40 years ago, I arrived in Chicago in search of an idea. I was a young man looking for purpose, who believed deeply in America, was inspired by the Civil Rights Movement, and wanted to be a part of something larger. The America I believed in was one where everyone has opportunity, everyone is seen, everyone belongs—because that was an America that had a place for me, too.
here's Michelle Obama's entire speech commemorating the opening of the Obama Presidential Center, which in part served as an extended (tacit) rebuke of Trumpism
The coronavirus vaccine reduced the risk of major cardiovascular events linked to covid-19 — strokes, heart attacks, and hospitalization from heart disease — by about 40 percent, according to new research. https://t.co/cQjvi8EMpX
My cautionary posts about SpaceX/Semiconductors seem to have struck a nerve.
Receiving many enraged/offensive e-mails.
Last time I saw this was in 2021 when I was warning about the meme stock/SPAC/ARKK manias.
History doesn't repeat itself, but it often rhymes.
Lloyd Blankfein, former CEO of Goldman Sachs, broke down his entire personal trading setup:
portfolio: 98% risky assets. 75-90% single stocks. mostly big tech hyperscalers plus "second tier" names slightly below blue chip.
"i invest in risky assets. that's what's fun for me."
"do you have a team? oh, just me."
hardware: no computer. an iPad and a phone.
information source: texting and calling people.
"somebody will text me. i'll text them. then i'll get tired of tapping things out because of my fat fingers. so i just call people up."
frequency: trades every single day. multiple times.
"it's taking a lot of discipline not to look at my screen while i'm talking to you right now."
"some people listen to music. to me, the market is like music. it's out there. it's going on."
has he outperformed the market? "yes, i have for a while. it's because of where i focused, tech, energy, and financial services. i know a lot about financial services having been in financial services."
the former CEO of Goldman Sachs. manages his own money. on an iPad. alone. focused on three sectors he actually knows. and beats the market.
sometimes the edge isn't the model. it's 40 years of pattern recognition and a phone full of the right contacts.
Julia Roberts: Renee Nicole Goode is not a symbol. She is an American woman, a queer woman who was doing the very best she could do to be good in an unjust world.
And I am honored to celebrate her life and her legacy tonight, because the life she gave is our responsibility to carry.
Rod Brind'Amour on winning the Stanley Cup as a coach compared to as a player:
"I've been asked that a lot here now. It's still awesome. It's just as awesome. But as a player, it was a little different because I'd worked and dreamt about winning the Cup my whole life. And so that was like a piano came off my back. This time around, I wanted it for the group. I wanted them to feel what it's like, and I wanted it so bad for them. So to watch them finally get it, and then when I'm grabbing it, just to see the look on their faces, it's priceless. Because you know how happy they were for me, and it was the other way around for me, you know? And I'll never forget that." #CarolinaCulture #SoundTheSiren #StanleyCup
It was great joining Njideka Akunyili Crosby — a gifted Nigerian-born, Los Angeles-based artist — to unveil our first portrait together. This piece reflects so many chapters of Michelle and my story, and we’re thrilled that it will be on display in the Hope and Change lobby at the Obama Presidential Center starting this Juneteenth.
🚨 Japan left their dressing room spotless after their match against the Netherlands. 👏
A tradition built on respect, discipline, and responsibility. ❤️🇯🇵
CURACAO SCORE THEIR FIRST EVER WORLD CUP GOAL AND IT'S AN ABSOLUTE BEAUTY!
THE SMALLEST NATION TO EVER QUALIFY HAVE SCORED AGAINST THE FOUR TIME WORLD CHAMPIONS 🇨🇼🔥