@heyhi_its_me@agingroy If you do hydroxypropyl-beta cyclodextrin and not beta cyclodextrin (which are different) then you will not face side effects. Do not administer beta-CD to yourself rectally
I am excited to share that CarboHyde will be participating in the BIO International Convention 2026, taking place from June 22 to 25 in San Diego, California.
If you would like to meet please reach out to me at [email protected] to set up a time.
Currently we are hosting two bright guys under the scope of the @Bicyclos_eu project.
Daniele Veclani and Andrea Trifoglio came from Isof CNR (@ilsemanet lab) and work on some new, fancy cyclodextrins - what else?
Cyclodextrins for enhanced CO2 management
Cyclodextrins are gaining attention as a promising platform for carbon capture, utilization, and storage (CCUS).
https://t.co/Cv8sOc8TmR
Check out this review to learn where we are today: https://t.co/Cv8sOc8TmR
Hungarian cyclodextrin science truly rocks!
Today, I am sharing updates from University of Szeged who made
Sulfobutyl-β-Cyclodextrin-Functionalized Albumin Nanoparticles
for intranasal brain delivery of carbamazepine.
How do you like this invention?
https://t.co/42FMtLXx4O
What if osteoporosis treatment could become both more targeted and safer?
New research on β-CDP (phosphate-functionalized β-Cyclodextrin) shows exciting potential for bone-targeted therapy in osteolytic diseases.
https://t.co/RZaWWM6sLv
It seems easy to make a cyclodextrin complex!
Oh, just nine simple steps, and you'll be all set to take your poorly soluble active ingredients to the market!
Because really, who doesn’t love a good challenge? 😉
At CarboHyde, we love this type of challenge!
Stabilization and Delivery of Anti-Vibrio Bacteriophage Therapeutics
This invention by @PhagePro (WO 2026/029901 A1) combines a three-phage cocktail (ICP1, ICP2, and ICP3) with a carefully engineered excipient coating, where hydroxypropyl β-cyclodextrin plays a central role.
Oops, we did it again.
This time with CNR and of course our dear Milo Malanga.
We explored the role, chemistry and biology of defensins, of course with the help of cyclodextrins, particularly succinylated-BCD polymer.
https://t.co/tZXqjN6ORE
HPBCD vs polysorbates
I came across this comparison by Hailong Zhang, where he evaluates HPβCD, which is a well-established excipient used in many approved small molecule drug products, against polysorbates as a stabilizer in biologics formulations.
https://t.co/vns6q6htkA
Ophthalmic Inserts with cyclodextrins
I was fascinated to read this paper from my alma mater, @semmelweishu who developed electrospun nanofiber-based ophthalmic inserts with gamma-CD to improve Amphotericin B eye delivery.
https://t.co/9qYURHqyen
Not often do I say this, but I have encountered something intriguing in cyclodextrin chemistry.
While I am not a synthesis expert, this development is remarkable.
Interior editing of cyclodextrins:
https://t.co/QYOgCa5ICx