Trey K

Post-Doc in NMR method development and spatial metabolomics. My own views. 🏳️‍🌈

[UEA NMR @UEA_NMR]

Dr @TTKoev and Dr Matthew Wallace from the #WallaceGroup at @uniofeastanglia showcasing their work on quantitative #NMR at the #qNMR 2025 summit in Bari. #NMRChat @nmr900

[UEA NMR @UEA_NMR]

Dr Matthew Wallace from @uniofeastanglia showcasing his group's work on aqueous pKa determination of water-insoluble drugs using chemical shift imaging #NMR at #JPAG 2025. #NMRChat

[César de la Fuente @delafuentelab]

For over a century, the hunt for new antibiotics has focused almost exclusively on bacteria and fungi. Today, that paradigm shifts. By coupling state-of-the-art AI with the vast, largely uncharted diversity of Archaea, we open a new frontier for molecular discovery.

Our APEX model sifted through hundreds of archaeal proteomes in silico, revealing a previously hidden family of antimicrobial peptides we call “archaeasins.” Of the 80 candidates we synthesized, 93% were active against pathogenic microbes in vitro, and one—archaeasin-73—matched the in-vivo efficacy of last-resort drugs such as polymyxin B.

These results show that the marriage of deep learning and evolutionary diversity can surface potent therapeutics at digital speed, expanding the antibiotic toolbox when humanity needs it most. Archaea, once thought biologically esoteric, now stand alongside bacteria and fungi as a rich reservoir of useful molecules.

We are excited to keep discovering antibiotics at digital speed with AI.

Link to the paper @NatureMicrobiol @NaturePortfolio: https://t.co/6BE2mO7GbR

[Markus Weingarth @MarkusWeingarth]

We are expanding our team at Utrecht University and we are looking for a Research Technician w/ interest in natural product isolation (especially lipids) for applications in drug development and pharmaceutical formulations.

Apply here:
https://t.co/ufw2QDFtv2

#jobs #technician

[Andy Lawrence @biomimetic_chem]

A postdoctoral position, funded by the @LeverhulmeTrust for up to 36 months, is available to join my group @EdinburghChem. The project focuses on biomimetic approaches to natural product synthesis.

Deadline: 28th August 2025.

https://t.co/S5GelmP6Cv

[UEA NMR @UEA_NMR]

Jonathan Hewitt from the #WallaceGroup at @uniofeastanglia giving his first talk of his PhD at the @RSC_NMRDG Student Meeting. He told us about the progress he has made into probing the structure and dynamics of #DNA #iMotifs using #CSINMR. #NMR #NMRChat

[UEA NMR @UEA_NMR]

Dr Trey Koev (@TTKoev) from the Wallace group at @uniofeastanglia giving a talk on problems with current consensus methods for testing #DrugDelivery vehicles, and novel #NMR methods of solving them. #NMRChat

[International Manuel Rico NMR School @rmnjaca]

📢 REGISTRATIONS are now OPEN!

Don't miss out the opportunity to attend #MRnmrSchool2025! 🧲

Secure your place on: https://t.co/DpsVzn8Jwd

#NMRSchool #MRSchool #NMRevents #NMRchat #NMR

[Trey K @TTKoev]

Interested in a new, easy to set-up #NMR method for probing crosstalk between #cells across distances?
Check out our new paper in @an_chem on spatially encoded NMR to probe colonocyte-commensal metabolic crosstalk in a simulated #HumanGut. #NMRChat https://t.co/0IR70Y6V3W

[Dominik Kubicki @DominikJKubicki]

🚨 PhD Opportunity 🚨 Would you like to join my group at @UoBChemistry? The school will support 3 exceptional applicants (typically 1st class honours or equivalent).
🗓️ Closing date: Midnight, 3 Feb 2025
🏆 Awards based on academic excellence.
📩 E-mail me for details.

[UEA NMR @UEA_NMR]

Check out the latest from us! Determination of the #pKa and Concentration of NMR-Invisible Molecules and Sites! #NMRChat #NMR https://t.co/NR6jkQLMcX

[Diego del Alamo @DdelAlamo]

Anyone have a walkthrough for setting up MD simulations on the cloud (not Google Colab or equivalent)? Personal pet project so can’t use my employer’s resources

[Stephen Robinson (he/him) 🏳️‍🌈 @RobinsonLab_QIB]

🧵 Exciting new preprint! 🚨 We’ve uncovered how Bifidobacterium pseudocatenulatum capsular exopolysaccharides (EPS) can enhance systemic anti-tumour immunity in pre-clinical breast cancer models. Here's what we found 👇 #cancerresearch #microbiome

[UEA NMR @UEA_NMR]

Haider Hussain, Dr Matthew Wallace and Dr Trey Koev telling us about all things #SpatiallyResolved #NMR at this year's #qNMR Symposium in Switzerland. @UEAPharmacy @TTKoev

[Cristina Paulino @CPaulino_]

Two open fully funded Postdoc positions in my lab in #cryoEM & #cryoET. See description below 👇Please share and spread the word. For all those interested in joining my group and work on exciting and collaborative projects please apply!
https://t.co/v3gfyQEG9T

[CRMN Lyon @crmn_lyon]

We have an opening for a  Research Engineer position! You will be in charge of maintenance and operation of the NMR instruments and work closely with the research groups of the center to develop advanced DNP NMR methods and applications: https://t.co/v5U7i7VLYE

[G. Pileio NMR Methodology Research Group @GPileioGroup]

Fancy doing a #PhD in #Southampton in a project half way between magnetic resonance, tissue engineering and micro fabrication technology? My colleague Yasir Noori and myself have an open position:
https://t.co/byP8kaie9v

[John Janetzko @jjanetzko]

My lab has multiple openings for those interested in doing some very cool science in beautiful Colorado!

Research assistants (tech/lab manager level): https://t.co/cf30hlFdzT

Postdoctoral fellows:
https://t.co/Tg9HlOGZAS

DM or email me if interested and 🙏 share broadly 🪃

[UEA NMR @UEA_NMR]

@TTKoev at @Euromar2024 sharing his exciting work on using spatially encoded #NMR to probe dynamic crosstalk between different cell populations in #RealTime, directly in an NMR tube. #Euromar #NMRChat #Euromar2024 @UEAPharmacy

[Maya 🐾🐹🦔💫 @Looking_at_soil]

Fodder oats as catch crop: potential to reduce nitrogen losses from soil https://t.co/Q6ZOSQnF8A