David Twesigomwe

Bioinformatician in the making 🌍🖥

[David Twesigomwe @TwesiDave]

@pgrnhub Many thanks to @pgrnhub, @PacBio and @TwistBioscience for supporting our research. Looking forward to uncovering new insights and advancing the PGx evidence base in Africa with a great team of collaborators.

PS: First grant (3rd time lucky for me) hits different!

[Scott Hazelhurst @shazeZA]

The last of our @H3Africa /GSK ADME Project papers, "Characterization of CYP2B6 and CYP2A6 Pharmacogenetic Variation in Sub‐Saharan African Populations" has just appeared. https://t.co/c017hdfqWS

[David Twesigomwe @TwesiDave]

@sproul_lab @EdinburghUni @mrc_hgu @EdinUni_IGC Congrats @sproul_lab 👏🏽

[David Twesigomwe @TwesiDave]

Such a treat attending the Mutational Scanning Symposium #VariantEffect23 at the @wellcomegenome with colleagues based at @mrc_hgu @EdinburghUni

[David Twesigomwe @TwesiDave]

Congrats to these talented young scientists on their graduation yesterday #MscMed_GenomicMedicine #classof2022 @WitsHealthFac

[AfriPopGen @AfriPopGen]

Looking forward to hosting @atelvee in our next #AfriPopGenWebinar on June 22, 2023 at 3pm CAT!

Register to join at: https://t.co/GaFuSssIBO

@asbcb1 @H3Africa @AfSHGenetics @GeneMAPOfficial @WACCBIP_UG @H3ABioNet @ICHG2023

[David Twesigomwe @TwesiDave]

So excited to present our #PGx poster on CYP2D6, CYP2B6, and CYP2A6 star allele characterisation in African populations at #ESHG2023. Wonderful meeting great colleagues @ChantalResearch and @synthymama 🙂

[David Twesigomwe @TwesiDave]

@synthymama presenting on the priorities for sickle cell disease #genetherapy in Africa @eshgsociety #ESHG2023 @GeneMAPOfficial @SickleInAfrica

[Scott Hazelhurst @shazeZA]

Come join our team!!!

[David Twesigomwe @TwesiDave]

Such an honour sharing this moment with my PhD supervisors @shazeZA and @dl_zane! Thanks also to my friends, family, colleagues and mentors for the great guidance and support.

[Scott Hazelhurst @shazeZA]

Congratulations to the @SBIMB1’s @TwesiDave for winning the most prestigious PhD thesis in the @WitsHealthFac prize giving for 2022

[David Twesigomwe @TwesiDave]

@nancybird_ @beleza_sandra Congrats 👏🏽

[AfriPopGen @AfriPopGen]

Very excited to host @cschlebu from @HumanEvoUU for our next #webinar on May 4, 2023 at 3pm CAT!

Register to join at: https://t.co/MZuHMdu2ag

@asbcb1 @H3Africa @AfSHGenetics @H3Africa @SAHumanGenetics @GeneMAPOfficial @humangeneticstz @genome_gov @TACG_Group @GenomicsEngland

[Segun Fatumo @SFatumo]

We @MRC_Uganda with @eventsWCS @AceUganda @Makerere are organising a Polygenic Risk Score (PRS) analysis workshop in Uganda.

The course is subsidised by Wellcome Connecting Science Courses and Conferences and is FREE to attend.

APPLY and Join us in Uganda

@H3Africa

[David Twesigomwe @TwesiDave]

@ClaudineN27 @ICHG2023 Thanks @ClaudineN27 🙏🏽 and thanks to everyone who made @ICHG2023 the best! This award would not have been possible without the support of @shazeZA, @dl_zane, @brittdrog, @GalenWright, @agaedigk, @SBIMB1, @WitsHealthFac, @H3ABioNet, @H3Africa, @SAHumanGenetics, and many others!

[David Twesigomwe @TwesiDave]

Such an honour presenting at the @H3ABioNet 10 year symposium! H3ABioNet has greatly contributed to my bioinformatics training, and opened doors for collaboration with (and learning from) scientists @UVRIug, @SBIMB1, @HPCBio, across Africa and beyond.
#H3ABioNet10YearImpact

[Scott Hazelhurst @shazeZA]

@TwesiDave and Nhamulo gave great presentations to the @H3ABioNet symposium on tools developed at @SBIMB1 to support African pharmacogenomics

[Scott Hazelhurst @shazeZA]

I'm very chuffed that the @SBIMB1 has contributed to two articles in Clinical Pharmacology & Therapeutics (
@ASCPT_ClinPharm) special issue on Diversity, Equity and Inclusion.

[Ed Hollox @edhollox]

Funded PhD project announcement time! Two potential projects available, @wellcometrust Public Health Genomics PhD prog @uniofleicester. Applicants from low-middle income countries welcome. @H3Africa @AfSHGenetics @SAHumanGenetics @eshgsociety @GeneticsSociety Please RT! 1/6

[David Twesigomwe @TwesiDave]

It was great meeting you too @SFatumo! Your mentorship and support of young African scientists is making a difference and setting a great example for us.

[Segun Fatumo @SFatumo]

Great to catch up with long time colleagues @manuelcorpas @TwesiDave @SBIMB1 at the @GenomicsEngland diverse data event #RGEC22 in London today.

[David Twesigomwe @TwesiDave]

This study highlights the distribution of POR star alleles in Africa and across global populations with a view toward informing future precision medicine implementation. Standardisation of the POR allele nomenclature is warranted given the #PGx importance of this gene.

[David Twesigomwe @TwesiDave]

Our #PGx paper on the Characterization of POR haplotype distribution in African populations is now out @PGSjournal. Congrats to @RossBooyse for excellently leading this research—such a pleasure co-supervising him with @shazeZA, @SBIMB1 @WitsHealthFac.

https://t.co/wf5TKAbLlI

[David Twesigomwe @TwesiDave]

Five novel rare POR haplotypes were computationally inferred from the African WGS data; five other unresolved diplotypes contained novel African-ancestry POR alleles. More novel POR alleles were identified in African populations compared to other global populations.