Underbite

[Underbite @underbite]

@murbster33 @krassenstein AHahahaaa! Good one. The #MAGACult's got nothing.

[Frank Campanello 🇺🇸🦅 @sportsgeek19]

@krassenstein Fake names, you say?

[MC @Chick43235]

@krassenstein So I guess that means JD Vance should immediately resign as well since he has changed his name 3 times

[The Tennessee Holler @TheTNHoller]

“The billionaires… the billionaires…”

[Brian Krassenstein @krassenstein]

Trump calls for Ilhan Omar to immediately resign from Congress for using the name Ilhan Omar.

So then, what should happen to somebody who was found liable of raping a woman, was found liable of hundreds of millions of dollars in fraud, and was found guilty on dozens of felony counts?

Death penalty?

[Mark Bourrie @MarkBourrie]

Get out and vote.
The slimiest people in Toronto want this guy to win.

[Gator⚡Gum @gator_gum]

There are RW Influencers that are literally hoping for shitty things to happen to Canada. They want pain. They want more struggle.

They're privileged and insulated from most of it, and therefore they literally want failure so they can tweet and rage bait over it and swipe at the PM of Canada.

How brutal.

[Laura Miers @LauraMiers]

The U.S. has been ignoring dramatically increasing TB since the Biden administration. The largest increases in TB have been reported in American children. TB is rampant in schools. California has reported large TB outbreaks with high attack rates. Covid reactivates latent TB.

[Miles Taylor @MilesTaylorUSA]

They kicked us out of the Washington Monument for filming this.

But Trump CANNOT stop us from releasing it next Tuesday.

One week before the election.

https://t.co/KcbWknrVLi

[Essenviews @essenviews]

Wolves roam into Finnish villages after Google destroys 1,300 acres of forest for AI data centers
https://t.co/0gy3f0vwxW

[Underbite @underbite]

This scene from #GOT seems somehow very relevant right now 🤔
#VoteBlueToSaveAmerica
#FascistGOP
#PedoPOTUS
https://t.co/VtMhFVmIur

[Bloom Lab @jbloom_lab]

Given some follow-up posts about this study, I am pasting as image below last paragraph of Discussion.

To elaborate, multiple studies (eg, https://t.co/WtzrYl5Gfm, https://t.co/dSJtv7Twtx) show primary exposure to new SARS-CoV-2 variants still elicits neutralizing antibodies, albeit w somewhat different specificities. I'm unaware of head-to-head quantitative assessments of human post-primary exposure homologous titers to newer vs older variants, but primary exposure to new variants still elicits decent homologous neutralizing antibody titers.

More generally, reduced inherent antigenicity to naive B cells is one mechanism (alongside glycan masking and positioning of RBD in more down conformation) by which evolution of human endemic coronaviruses can affect antibody elicitation. Understanding these mechanisms can improve vaccine / antibody development, and is scientifically interesting. However, newer viral variants remain immunogenic, albeit probably at modestly reduced levels--so this work does not support alarmist interpretations about the immune system no longer recognizing SARS-CoV-2. The human antibody response has an amazing ability to recognize highly diverse antigens, although it can certainly recognize some more easily than others.

[Bloom Lab @jbloom_lab]

In new study, we show that SARS-CoV-2 has evolved decreased inherent antigenicity in humans, as quantified by a ~3-fold decrease in the number of naïve human B cells that can bind the spike RBD.

https://t.co/OabX5bSYwp

[tern @1goodtern]

Interesting to see this in writing, but it was obvious it was heading this direction via chronic infections.

Covid is evolving to avoid even more of the inbuilt immune responses.

Expect more and more chronic infection.

[Essenviews @essenviews]

Kyiv denies reports that Trump, Musk have restored Starlink speeds in Ukraine
https://t.co/2g1LwDaQxY

[Jack Hopkins @thejackhopkins]

On Tuesday, in a hotel conference room in Little Rock, FEMA’s administrator told every state emergency chief in the country to build their own reserves and expect fewer federal declarations.
No press conference.
POLITICO got the tape.
If a river, a coast, or a fault line runs through your state, this is the most important thing you’ll read this week.

[Vicki Campbell🇨🇦 @merry123459]

If Torontian don’t remember or know about the Walkerton water disaster that killed multiple people and left many others with lifetime defects, they may want to do some research before they vote for Brad Bradford and his water privatization idea.

[Brown Eyed Susan @smc429]

TRUMP LIES

[Judd Legum @JuddLegum]

Ramaswamy has produced an attack ad weaponizing the rape of his opponent, Amy Acton, when she was 12 years old. It features Acton’s mother, who abandoned Acton after she was raped by her step-father, fleeing the state with her husband.

Here is the corporate money helping fund that ad.

[Billy Hanlon @bhanlon15]

NPR: 'The dormant viruses in all of us may help explain long COVID'

14-minute listen ft. Akiko Iwasaki.

Host Nathan Rott shares that he has family members impacted by Long COVID

https://t.co/UaZQYtVl8L