📢 Small NF PanNETs can/should be observed
#ASPEN🏔️ @spartelli#ESMO25
👥Prospective multi-centre cohort 1️⃣0️⃣0️⃣0️⃣ PanNETs <2cm
An image 🏞️ is worth 1000 words👇🏻
For resection:
😳NNT 276
⚠️NNH 6
✅No difference in OS surgery vs active surveillance
👏Congrats on landmark work!
Excited to present at #ESMO2025 the results of the ASPEN study on 1,000 patients with pancreatic NETs <2 cm.
What do you think the data will support? Surgery 🔪 or observation 🔭
@myESMO
Grateful for another inspiring #ItaNET meeting🇮🇹 Honoured to receive the Best Poster Award🏅for our #3DpNETModels🔬work!
Fantastic talk by @valentinandreas on🔪of small pNET🔥exciting studies from our group on💰toxicity & borderline✂️
Proud to be part of @MyUniSR team✨@spartelli
Most looking forward on this list to the results of #ASPEN 🏔️ - final analysis of multicentre prospective cohort of observation for small sporadic non functional PanNETs🦓
Congrats on the #ESMO25 late-breaking abstract @spartelli!👏🏻 ✨
Grateful for an inspiring @sito_trapianti meeting! Honoured to have presented our research on graft pancreatitis and to receive the Best Abstract Award! 🏆 And very proud of our team sharing the first 💯 transplants at @SanRaffaeleMI! 🚀@spartelli
Surveillance over right hemi for appendix #NETs 1-2cm - not only safe but cost-effective💰
Markov analysis from 🇮🇹
✅Survival is same >98%
✅Surveillance cost-effective - ⬆️with longer FU
Varies in 🌎👉🏻less cost-effective South Asia & Africa
📝🔗 https://t.co/fgp0JCsrUb
Thrilled to have attended #IPITA2025 in Pisa, presenting our work on graft pancreatitis!
Grateful to have shared this experience with my mentor @StefanoPartelli and with friends from @UniSR.
Heading home 🇮🇹/🇬🇧 full of motivation for the next steps ahead! 🚀
☢️ Is there a role for ablative radiation therapy for technically resectable pancreas cancer?!
🇺🇸 25 pts T1-T2 with comorbidities (❌surgery)
👍 2-year local progression 20% overall survival 43%
😱 Very provocative read!
https://t.co/HrYVpghI47
🦠 Microbiome plays a role in pancreatic surgery for PDAC - Enterococcus in bile → ⬆️ SSI
→ ⬇️ OS
🚨 Highest risk: Preop ERCP + E. faecalis in bile aspirates
💊 THM: Consider piperacillin-tazobactam for periop prophylaxis
#PDAC#microbiome#surgery
https://t.co/pFAIEGsKak
Can we predict🔮 early progression ⏰after surgery for PanNET with LM?
🇮🇹54 patients
👨🏼🦳Age >70⚠️risk factor
👩🏼🦰Female gender 🛡️protective, even with bilobar LM
⚔️Is a more aggressive surgical strategy justified in younger patients/females?
https://t.co/gWqeXXhUPy @spartelli
Because you can resect does not mean you should
Not all NETs are the same
@spartelli introducing biological unresectability for PNETs at #ENETS25 👉🏻 identifying futile surgery & when preop therapy will help
We have 💊options - let’s figure out how to combine with surgery!
Not all nodal metastases are equal for #PNETs - @valentinandreas@spartelli at #ENETS24
Resected PNETs:
🔬micromets (<5mm) have same DFS as N0
➡️Not all nodal disease is clinically meaningful
⚠️Important info in discussing extent of surgery & LND
Stefano Partelli summarizing the ENETS SurvivApp study on appendiceal NET 1-2cm before the #ENETS will close. This study will lower the rate of hemicolectomies in these patients. @inselgruppe@igmp_unibern