van Dam Lab

[van Dam Lab @vanDamLab]

Our droplet-based implementation of the Cu-mediated radiosynthesis of [18F]FBnTP, including a new scale-up approach to achieve clinical dose amounts, was recently published in Lab on a Chip: https://t.co/4Qj9zoYdS0. Congrats to the whole team!

[van Dam Lab @vanDamLab]

Our collaborative work with ETH Zurich, using droplet radiochemistry to efficiently optimize the synthesis of their novel MAGL PET tracer, was recently published in Lab on a Chip: https://t.co/XDPEsscnTx. Congratulations to my student Joanne Lu who spearheaded this project!

[van Dam Lab @vanDamLab]

Our development of a robotic system for automated high-throughput chemistry (up to 64 reactions in a few hours) was recently published in Chemical Engineering Journal (https://t.co/Tw8LP6QbH4) and presented at the ISRS 2023 meeting. Congratulations to Jason Jones and the team!

[van Dam Lab @vanDamLab]

We just published a proof of concept of using high-resolution TLC separation as a way to purify microfluidically-produced radiotracers, without the size/cost of an HPLC system: https://t.co/iUxQt0jV8N. Congratulations to Travis Laferriere-Holloway and the whole team!

[van Dam Lab @vanDamLab]

Our research in mobile phase optimization using the PRISMA method to maximize radio-TLC resolution was recently published: (https://t.co/K4uoR6kGa1). Congratulations to Travis Laferriere-Holloway and the whole team! Congratulations also to Travis on his PhD defense last week!

[van Dam Lab @vanDamLab]

Our work on development of high-throughput methods for radiochemistry optimization (using droplet-based approaches) was just published in Scientific Reports: https://t.co/x798CGpTWJ. Congratulations to my student Alejandra Rios and the whole team!

[van Dam Lab @vanDamLab]

Our collaborative work with SOFIE, Inc. on developing and evaluating a robotic platform for microvolume radiochemistry (PHENYX) was just published in Chemical Engineering Journal: https://t.co/WHhqocQAxw. Congratulations to the team!

[van Dam Lab @vanDamLab]

Congratulations to my graduate student Alejandra Rios who was selected as one of the Student Research Competition winners at @Pacifichem 2021 for her presentation on "High-throughput approaches for the optimization and analysis of radiopharmaceuticals"!

[van Dam Lab @vanDamLab]

Our book chapter detailing the methods for our droplet-based radiochemistry approach has just been published in "Biomedical Engineering Technologies" Vol 1. https://t.co/BKdCuySHTV Congratulations Jia!

[van Dam Lab @vanDamLab]

Our work showing clinical-scale (and quality) production of [18F]FET and [18F]Florbetaben using droplet radiochemistry was just published in Scientific Reports (https://t.co/wpTjLPX0ov). Congratulations to Ksenia, Jia, Joanne, and our collaborators at SOFIE and Trace-Ability!

[van Dam Lab @vanDamLab]

The video protocol accompanying our recent JoVE paper was just released, showing how we perform parallel radiochemical reactions in small droplets for synthesis optimization: https://t.co/uqxHfGRmhu

[van Dam Lab @vanDamLab]

Excited to be giving a plenary talk tomorrow on droplet radiochemistry at the Australian and New Zealand Society of Nuclear Medicine (ANZSNM) annual meeting 2021! https://t.co/Zbcu3H3rHl

[van Dam Lab @vanDamLab]

At the eSRS conference May 17-19, 2021 (https://t.co/Cg9FLArADY), our lab will be giving 7 presentations on recent developments in radiochemistry miniaturization, high-throughput radiochemistry, and analytical methods. Full list here: https://t.co/BoSw6eBHGE.

[van Dam Lab @vanDamLab]

Giancarlo Pascali, Yuji Kuge, and I are hosting a symposium during Pacifichem 2021 focused on "Innovative Technologies for Production, Purification, Analysis and in Vitro Evaluation of Radiopharmaceuticals". Abstract submissions are open until Apr 12 (https://t.co/HZoXECfUZj)

[van Dam Lab @vanDamLab]

My colleague Arion Hadjioannou and I just published a review in Frontiers of Physics on the many applications of Cerenkov imaging in understanding and optimizing microscale radiosynthesizers, and in analyzing radiopharmaceuticals (via TLC). https://t.co/wF1Ni0h6Jl

[van Dam Lab @vanDamLab]

Congratulations to our lab member Ksenia Lisova, who just successfully completed her Ph.D. defense in the Physics and Biology in Medicine (PBM) program at UCLA! Very well done!

[van Dam Lab @vanDamLab]

We have been developing new methods for efficient high-throughput optimization in radiochemistry based on droplet reactions. A detailed protocol has just been published in JoVE (video version coming soon): https://t.co/1BzwCTAY1V. Thanks to Alejandra Rios and the whole team!

[van Dam Lab @vanDamLab]

Our review of droplet-based synthesis approaches in the radiochemistry field was recently published in the journal Molecular Imaging. Thanks to my former postdoc Jia Wang for all of her hard work on this! https://t.co/JY0K26ySTn

[van Dam Lab @vanDamLab]

Our work in scaling the amount of activity in droplet microreactors for radiochemistry was just published in RSC Advances. We demonstrate the production of >7 GBq of the PET tracer [18F]Fallypride (enough for multiple patient doses) in an 8 uL reactor. https://t.co/cooNL9fgWa

[van Dam Lab @vanDamLab]

Our project on microchip electrophoresis (MCE) for analysis of radiopharmaceuticals was just published in Analytical Chemistry. In collaboration with Arion Hadjioannou, we integrated a radiation detector for simultaneous positron and UV detection. https://t.co/tffqa2QpTv