Gaurav

Interested in zebrafish, gene editing, and disease modeling. Opinions are my own and not the views of my employer.

[Gaurav @varshneylab]

@PracheeAC Happy Diwali, Prachee!

[Wolf Prize @WolfPrize_]

ANNOUNCING THE 2026 WOLF PRIZE LAUREATES IN CHEMISTRY
The 2026 Wolf Prize in Chemistry is awarded to Pascal Mayer, Shankar Balasubramanian and David Klenerman for developing impactful, low-cost, next generation DNA sequencing methods for genomic medicine.
Their work helped transform DNA sequencing into a technology capable of operating at extraordinary speed and scale.
Balasubramanian and Klenerman pioneered a massively parallel sequencing approach that contributed to a million-fold improvement in sequencing speed and cost, helping make it possible to sequence a human genome for under $200.
Mayer played a pivotal role in turning those breakthroughs into a practical high-throughput sequencing system, integrating the chemistry, microfluidics, optics and computational components needed to make the technology work at scale.
Today, the sequencing platform that grew from this work forms the technological foundation for more than 90% of global sequencing data, powering major advances in genomics and precision medicine.
Congratulations to the 2026 Wolf Prize Laureates in Chemistry!

@Cambridge_Uni @universitedestrasbourg

[Ankit Sabharwal @ankitsabharwal9]

🧬🐟 This week marks # WorldMitochondrialDiseaseWeek (Sept 14–20). @scekker and I are excited to share our team's new preprint
Z-Terminator: Systematic Engineering of Loss-of-Function Alleles in the Zebrafish Mitochondrial Proteome
https://t.co/AsZbTFX5my
#Mitochondria #Zebrafish

[OMRF @OMRF]

OMRF scientist Dr. Gaurav Varshney developed a method that could one day help make rare genetic disease diagnosis faster and more precise. With a new grant from the NIH, he aims to make this platform available to others who study genetic diseases.

https://t.co/wTHbdCrCLx

[Varun Varshney @varunux]

Streaming gave us everything to watch and somehow made 100 years of cinema invisible.

I built Oddflick to bring it back: swipe through classic film scenes, tap when one catches you, and watch the whole movie.

Free on iPhone.

[Gaurav @varshneylab]

What happened to Ensembl? 😭 Why was it destroyed? I came here to browse a genome, not fight for my life against the bad UI.

[Gaurav @varshneylab]

The Burgess lab has released a new zebrafish genome assembly, GRCz13ab.

[OMRF @OMRF]

On Aug. 28, 1946, OMRF answered the call to people who “were dreaming of a world in which medical advances would alleviate pain and disease.” Since then, we've continued developing new ways to prevent and treat diseases of aging, autoimmune illnesses, cancer and heart disease.

[OMRF @OMRF]

Catch up with the president, see what our scientists are up to, and hear more about how one of our board members races around the world to stay young.

Check out the digital version of our latest Findings magazine now! https://t.co/mrF7KkJ1LA

[Gaurav @varshneylab]

Feng Zhang and David Liu will both get it eventually.

[Anusha @__acbraingenome]

how come Zhang et al. hasn’t won a Nobel Prize yet? 👀

[David R. Liu @davidrliu]

Today in @NatureBiotech we report OptiPrime, a mechanism-based machine learning model for predicting prime editing (PE) efficiencies and suggesting pegRNAs to achieve a user-specified edit. OptiPrime incorporates biochemical knowledge about PE into its mathematical structure, enabling training on ~300,000 PE efficiencies collected using 40 experimental conditions in multiple labs, and outcome predictions of PE variants such as twin prime editing not used in its training. OptiPrime enabled the rapid identification of efficient PE strategies across a variety of applications in vitro and in vivo, and could outperform months or years of manual experimental optimization.
Try out OptiPrime here: https://t.co/ahQPQ9MjYW
PDF: https://t.co/0xHQa5og0f
1/15

[Gaurav @varshneylab]

Heartbreaking news! Dan was an absolutely legendary scientist and amazing person.

[Autoinflammatory All @AAlliance_SAID]

We are saddened to announce that Dr Daniel Kastner, MD, PhD, a legendary, brilliant & kind-hearted physician and researcher passed away this Sunday. Dr Kastner will be greatly missed, but his impact is beyond measure, & everlasting. 🧡 https://t.co/xETuIalSmn
#autoinflammatory

[Gaurav @varshneylab]

@kapahi_pankaj Congratulations!

[Gaurav @varshneylab]

The Burgess Lab has just updated the ZebrafishGenomics public data hub for the UCSC browser (available all the way at the bottom here: https://t.co/no0vrr3qlU). They added several useful tracks, including CRISPR guides and variants.

[Sarah Ocanas, PhD @OcanasSR]

Reach out to me if you are interested in applying for a Nathan Shock Center Pilot Award with the @OKNathanShock Genomic Sciences Core! Up to $20,000 in omic services for aging studies!

[Gaurav @varshneylab]

In 2021, the journal Development published a special issue, “The Zebrafish Issue: 25 Years On.” Unfortunately, all the articles are behind a paywall. At the very least, special issues like this should be made open access. https://t.co/NbHb82cds5

[IZFS @InfoIzfs]

TOMORROW: FREE #IZFSwebinar planned by the @EZS_YoRC. Join the Franklin-Prasher-Kimmel (#FPK) Series tomorrow at 10 am EDT with speakers Stefan Choy and Wei Qin. Read more and register here: https://t.co/3kOAB90ZKA

#zebrafish #zebrafishbiology

[Gaurav @varshneylab]

Excited to share that Dr. Wei Qin (@qinwei007007) from my lab will present his base editing work on June 25!

[IZFS @InfoIzfs]

Join us for a NEW IZFS WEBINAR: Franklin-Prasher-Kimmel (FPK) Series! On June 25th at 10 am EDT with speakers Stefan Choy and Wei Qin. Read more & register here: https://t.co/Jwr3Ta9gRV

This IZFS Webinar is FREE to all registrants, thanks to the #YoRC!

#IZFSWebinar #Zebrafish

[IZFS @InfoIzfs]

Your vote is vital! The 2026 IZFS Board of Directors Election is open and we need your vote! Meet our candidates and vote here for our next President-Elect, Treasurer and four Regional Representatives: https://t.co/3kerlB9XEY

#IZFSElection #VoteNow #BoardofDirectors #Zebrafish

[OMRF @OMRF]

OMRF scientists Drs. Chi Fung Lee and Hina Nizami have discovered a way to reverse the effects of heart disease in diabetic mice.

Read more: https://t.co/bENsJkSmJO