Sriram

A perpetual student of science learning a lot of immunology every day. Developing immunotherapeutics

[Sriram @vesriram]

overall - claim that cellular aging states at tissue level can be decoupled via circulating plasma proteins is vulnerable to confounding by so many factors: cell-type shedding dynamics, vascular permeability changes, and causality interpretation artifacts.

[Sriram @vesriram]

I'm a bit skeptical about extrapolating cellular aging from plasma proteomic signatures. not a bioinformatics expert but logic tells me that there are significant gaps in our knowledge for categorically claiming signatures = something specific . https://t.co/xYUdCRk3bh

[Sriram @vesriram]

That said - it's an elegant work especially from orthogonal validation standpoint. biomarker discovery is notoriously platform-dependent. one would doubt aptamer platform would behave similar to an antibody platform but the authors have done robust cross-platform validation

[Sriram @vesriram]

https://t.co/o5IbpbZ4ZR - A patient with 10 years of clinically diagnosed adv AD was treated with mushroom and reported to be autobiographical and improvements in other functional activity (transient). N=1 study

[Sriram @vesriram]

@Niraja_karthik கீரை கூட்டு (அ ) மிளகு குழம்பு

[Sriram @vesriram]

Bird brain

[Sriram @vesriram]

In Chennai on a personal trip. Any biotech VCs, founders, students who want to chat - connection appreciated. Would love to get to know the ground realities.

[The Hindu-Hyderabad @THHyderabad]

CCMB scientists identify rare gene behind #Indian girl’s red hair

@geetanathvallur
https://t.co/0ZXAYWqq88

[Sriram @vesriram]

Wockhardt secures US FDA approval for antibiotic Zaynich - A proud moment for many https://t.co/zjjMHsvo0a

[Sriram @vesriram]

பொறுப்பும் இல்ல பருப்பும் இல்ல - Gericare hospital in Chennai

[Sriram @vesriram]

Artwork installed at @CSMIA_Official Chhatrapati Shivaji Maharaj International Airport Mumbai is amazing. World class and i wish more ppl appreciate it

[Sriram @vesriram]

As the authors cite attributing to Henri Poincaré, a collection of facts is no more a science than a heap of stones is a house. Modern biology has become an astonishingly massive, multi-billion-dollar heap of stones. -end-

[Sriram @vesriram]

Biology Needs Philosophy, But What Philosophy? https://t.co/7aNaeNUCLw

[Sriram @vesriram]

When finding statistical correlations across massive datasets replaces mechanistic and causal theorizing, our field begins to mistake technical resolution for conceptual understanding. 10/n