Another failure for TIGIT as a target as Skyscraper-03 failed to improve survival for pts undergoing CRT for NSCLC when adding anti-TIGIT to PD-L1-inh.
So far, neoadjuvant chemo-IO is given to pts with respectable disease. But could it also be used for downstaging of borderline respectable disease? That is explored in the MDT-bridge trial. Borderline respectable pts where given 2 cycles before new MDT. 71% got surgery.
Tarlatamab continues to impress. In the Dellphi 303 study where Tarlatamab was given with chemo and PD-L1 inhibitor from the start in 1L.
👉12m OS 81%
NB! Phase 1b non-randomised, n=96.
This promises a new era for our patients!
Zongertinib and sevabertinib are both promising as HER2-TKIs also in 1L. Presented by Sanjay Popat and Xiuning Le. Awaiting results from phase 3 trials.
No survival benefit of adding atezolizumab to CRT for SCLC-LD in the ACHIlES-Trial presented by Bjørn Henning Grønberg at #ASCO25 today. The discussant stressed the exceptionally good outcome in the control arm, the benefit of PCI and the possibly of twice-daily fractionation.
Prognostic value of FDG-PET before treatment with ipi/nivo +/- the UV1 vaccine for pts with mesothelioma. Congrats Solfrid Thunold! https://t.co/bB4Tt6ujIS
Ultimovacs kunngjorde tirsdag kveld at det har vært en signifikant og klinisk relevant økning i totaloverlevelse blant pasienter med brysthinnekreft som mottok kreftvaksinen UV1 i fase 2-studien NIPU.
https://t.co/qoaNgpawOm
Åslaug Helland fikk i dag overrakt Kong Olav´s kreftforskningspris av Kong Harald i Universitetets Aula. Gratulerer, Åslaug - vel fortjent!
@HellandAslaug
Today, @HellandAslaug received the prestigious King Olav V's Cancer Research Prize from King Harald V of Norway. A well-deserved recognition, congratulations!
Alkohol har en negativ effekt på hele 200 sykdommer. Gitt det er det en naturlig konsekvens at kostrådene, som er der for å ivareta hensyn til helsen, anbefaler avhold.
https://t.co/hY7YnNHrnI
@BHGronberg Great study with important information to all clinicians!! Do you have a screening-log indicating if the inclusion rate in your trial was different for older than younger patients?