Vishvak Subramanyam

Biomedical Informatics PhD student @UCSF & @arcinstitute

[Johnny Yu @iamjohnnyyu]

1/3 Our Tahoe-100M paper is out in Cell today, in a special edition dedicated to modeling human cell. We released Tahoe-100M last year. It has been downloaded 600K+ times and it has become the basis for most serious efforts in building cell state models. We are proud of that. @tahoe_ai

[Ryan Corces @ryancorces]

Just posted a preprint on a huge new single-cell study of Parkinson’s and its application to understanding noncoding variation. 🧵below. Led by Shreya Menon and Adam Turner and in collab w/ GP2 (@ASAP_Research), @BelloyMichael, @ZihHuaFang and others. https://t.co/tBKZgq5bQ7

[Hani Goodarzi @genophoria]

Preprint drop from our team at @arcinstitute! Introducing STATE: a model that learns and predicts transcriptomic responses to chemical or genetic perturbations. This is the first model to beat simple linear baselines and our first step toward building a virtual cell model.

[Arc Institute @arcinstitute]

Introducing Arc Institute’s first virtual cell model: STATE

[Noam Teyssier @noamteyssier]

I'm excited to release what I've been cooking up the past few months at @arcinstitute

BINSEQ is a family of binary file formats for sequencing data built with paired records and parallel processing in mind with big performance gains (2x-40x) over gzip-fastq with similar storage

[Davide Ruggero @RuggeroDavide]

Happy to share our new work with @haognguyen on targeting mRNA translation of oncogenes by RNA structure remodeling with a small molecule zotatifin. Congrats to ⁦@DuyguKuzuoglu⁩ an amazing postdoc and all the authors and collaborators!

https://t.co/RGH6wZqkLl

[Nature Cell Biology @NatureCellBio]

☕️@ScientistJoanna, @RuggeroDavide & co perform a genome-wide CRISPRi screen and identify RBM42 as a ribosome-associated protein that modulates MYC translation and an #oncogenic mRNA program required for #PancreaticCancer growth.
👉🏼https://t.co/SWt5DxRqpF
https://t.co/IHcOfFPdDn

[Davide Ruggero @RuggeroDavide]

Thanks Levi Gadye, for the wonderful and insightful highlight of our last publication! @UCSF

https://t.co/mQtyA7yCS6

[Joanna Kovalski @ScientistJoanna]

We are excited to share our new work out today in @NatureCellBio uncovering a new Achilles heel of pancreatic cancer. Myc is a key driver of PDAC and predicts poor survival. Thus, we asked the question of how Myc protein levels are regulated in PDAC.
👉 https://t.co/EMqDE5hX9M 🎉

[Hani Goodarzi @genophoria]

Our latest from the indefatigable @iamjohnnyyu in collaboration with @JswLab and @kevansf. Meet GENEVA, which enables simultaneous phenotyping and profiling of cancer cell drug responses at scale; both in vitro and in vivo across a variety of models: https://t.co/KswU7qtIRE

[Hani Goodarzi @genophoria]

The final version of is now published: https://t.co/CW0xH4MqYo
Congratulations @khorms57 and our team across 3 groups, ours, @FKHM, and @halfacrocodile!

[Hani Goodarzi @genophoria]

Folks about to graduate with bioinformatics/data science backgrounds who are interested in research, please apply: https://t.co/CljPxtxLoG

[Arc Institute @arcinstitute]

We’re thrilled to welcome Hani Goodarzi @genophoria, Associate Professor of Biochemistry & Biophysics @UCSF, as our newest Core Investigator

His groundbreaking research uses machine learning models and experimental frameworks to dig into cancer progression and metastasis.

[Arpana Church @ArpanaChurch]

congratulations @Michelle8Guan on your work highlighting #resilience and #braingutmicrobiome alterations with Physical Activity
https://t.co/GEFxKZvoIm @UCLAHealth @UCLAFSPH @UCLAGIHep @TienDongMD @DOM_UCLA @uclaimchiefs

[Hani Goodarzi @genophoria]

Check out our latest paper in @NatureCellBio exploring the link between alternative polyadenylation, translation efficiency, and metastasis. https://t.co/0tmJUj4KwG

[Hani Goodarzi @genophoria]

Check out this shiny new shiny app @vishvak2000 and @khorms57 have put together... go check out your favorite RBPs!

[Matvei Khoroshkin @khorms57]

Thanks to @vishvak2000 we are also releasing an RNA binding protein (RBP) browser for dynamic visualization of RBP-RBP interactions in our preprint (1/7) https://t.co/BMlAeZ9jIQ

[Hani Goodarzi @genophoria]

We have open positions for Jr Specialists in our group, both wet and dry. Anyone who is interested, feel free to reach out.
https://t.co/UgnLjqJ3Hx
https://t.co/CljPxtyjee

[Elsevier News @ElsevierNews]

New research in @BiologicalPsyc1 shows how discrimination affects the brain-gut microbiome-immune system. Suggests discrimination contributes to health inequalities & psychological symptoms:https://t.co/TCKIfjAGmh

@AGuptaCNS
@TienDongMD
@vishvak2000
@emeranamayer

[Arpana Church @ArpanaChurch]

how does discrimination effect our biology and make us sick 👉https://t.co/aGfsNFc3jY
@NIMHD @NIMHDirector @TienDongMD @GilbertGee6 @UCLAGIHep @ucladomedi @UCLAHealthNews @ucladgsomdigest