Vinayak Kulkarni

Engineer at heart, currently building @revelation.health.
Previously @southparkcommons. @Invitae @Agilent @Merck Research @illumina

Views expressed are mine.

[Vinayak Kulkarni @vkullu]

@ashpreetbedi Isn't he saying if you rent the intelligence you give away your intelligence? You need to own the intelligence too.

[Vinayak Kulkarni @vkullu]

@adityaag it's there already imo, both anthropic and openai have primitives I used to do async agents in cloud for long running "hill climbing" sort of jobs. Only question I deal with is helping set the right iterative loop so the recursion can make meaningful improvements.

[Vinayak Kulkarni @vkullu]

The most talent sense community which supports each other scale their own mountain. Do hard things, fail at hard things, try again. Apply and be a part of something bigger than you've ever done.

[Aditya Agarwal @adityaag]

Every founder I meet worries about missing this moment.

The best worry about wasting it. There’s a difference.

It’s a waste to ignore how much the world has changed. It’s a waste to think you can capture value with pure software the same as 5 years ago.

It’s a waste to build something small.

We have seen the shift slowly and then very quickly at @southpkcommons.

Here’s who we want in the Founder Fellowship now: hardware tinkerers, mad scientists, obsessives, biohackers, people who build nuclear reactors in their basements.

People who want to get their hands dirty and touch grass and atoms.

If you are only building software, then please (for your own sake!) have a thesis that all your friends laugh at you about. Heresy is the price of ambition.

Then put yourself in the right environment to maximize your ambition.

(Apply by August 2nd)

[Vinayak Kulkarni @vkullu]

@jxnlco I have a huge requirement for this at Natera. Can it work in the background and still allow me to do my tasks without hijacking the browser?

[Vinayak Kulkarni @vkullu]

@mitch_troy We have roles at Natera for a team I am building for exactly this purpose. Do you mind introducing us? Thank you.

[Vinayak Kulkarni @vkullu]

Recommendation pipelines courtesy LinkedIN :). I'd love to be connected with @SnoopDogg and understand more about sales order processing.

[Vinayak Kulkarni @vkullu]

@iuditg For the throughout you would need at that scale of the company as well as all the extremely complicated work that goes in inferencing at scale efficiently, this is far from just buy your GPUs. Twitterverse makes your believe otherwise.

[Vinayak Kulkarni @vkullu]

@adityaag Like your hot takes a few months ago with @evantana are you going to do updated priors session soon from your travels? Please do!

[Vinayak Kulkarni @vkullu]

@AgrawalArian I literally had it tell me after I asked clarification (third time) -- I am checking if I was saying to truth or making it up.

What!?!? This is Claude Code on Opus 4.7.

[Vinayak Kulkarni @vkullu]

@AgrawalArian @jxnlco @southpkcommons Jason helped us at revelation health as well to ideate on structured parsing of medical records. I wish I could join in person. Thank you @jaso

[Vinayak Kulkarni @vkullu]

@AgrawalArian I'd prefer that with humans too!

[Vinayak Kulkarni @vkullu]

@AgrawalArian @tryprofound @dbabbs @soleio @southpkcommons What's the story behind the mail?

[Vinayak Kulkarni @vkullu]

@adityaag Aditya, I also thought for all the fanfare I see about computer use, it's not as reliable and context effective to do any real work. That is also the next frontier than just integrations via tool calling

[Vinayak Kulkarni @vkullu]

@anshulkundaje @EricTopol More of this please!

[Vinayak Kulkarni @vkullu]

@adityaag Most interesting aspect of openclaw architecture was the pi can rewrite a skill/feature and deploy it immediately so you have infinite versions of the same starting base claw across users. How do you test for this, if you were an enterprise? Fun times!

[Vinayak Kulkarni @vkullu]

@sarahwooders @sarahwooders I have always been a fan of memGPT/Letta and have included it in the architecture of a few systems I have built. I see recently you have moved to coding agents. What happens to the generic harness and tools y'all built past 3 years?

[Vinayak Kulkarni @vkullu]

@AgrawalArian @ashwinl https://t.co/Jq7gFIxKcI. Along the lines you are thinking but starting with genomics. I know the founders very well (coworkers at Invitae). Holler, if you are interested and I can connect.

[Vinayak Kulkarni @vkullu]

@pritopian @pritopian -- This is an amazing ad! So so well done from start to finish! Good luck.

[Vinayak Kulkarni @vkullu]

@garrytan The unfortunate truth still is though, how companies hire, even for big tech hasn't change (personal experience).

[Vinayak Kulkarni @vkullu]

@evantana @adityaag @southpkcommons Have fond memories of this day back in Fall 2023. Good luck to everyone in the -1 to 0 phase. May the force be with you!