Karen Crum

Global Strategy, Partner @ EY exp. McCann, Ogilvy, Xbox, Nestlé, Coca-Cola BBC ft. musician, football & golfer Spotify:

[Karen Crum @vonburl]

@TimesRadio @AasmahMir ‘Two things can be true at once’ ❤️ @AasmahMir - your show with Stig was exceptional. I’ll miss how you brought great depth and insight to difficult subjects, but also managed to make room for laughter. Best of luck with whatever you do next.

[Karen Crum @vonburl]

@mrianleslie @tracey_thorn This is wonderful

[Sophie Wilkinson @sophwilkinson]

when you go to ppl's 'childhood friends' for a statement of their adult behaviours you're basically going as close to their beginning as possible, in order to confirm the sexist bias that it's their mum who fucked them up. when it's society, not mums, who train men to be vicious

[Karen Crum @vonburl]

@zoescaman So sorry to hear that - sending you all love ❤️

[Karen Crum @vonburl]

@Will_Humphrey Happy birthday!!!

[Karen Crum @vonburl]

‘Genetically sarcastic’ - never have two words captured the Northern Ireland disposition as perfectly as this.

[The author, Séamas O'Reilly @shockproofbeats]

Not knowing what else to do, she smiled and said she’d read it out to the whole class. I said please no don't. But she did, and even they - a room full of Northern Irish 7-year-olds, so genetically sarcastic as to be basically evil - seemed genuinely worried for my mental state.

[Karen Crum @vonburl]

@Will_Humphrey Wish I’d heard it!

[Karen Crum @vonburl]

@Robertc1970 Amanda Jones, CSO at McCann Canada would be good to chat to. Happy to connect you

[Karen Crum @vonburl]

@Will_Humphrey Thanks, Will! So lovely to meet you in person. Really enjoyed our chat.

[Sean Leahy @thepunningman]

Today is gonna be the day that they're gonna throw it back to you

[Karen Crum @vonburl]

@MattHaighPoetry I’m reading this at the moment and think it covers some of those themes. It’s exceptional! https://t.co/mgC6KlEW33

[Karen Crum @vonburl]

@sounder_golf I concur

[Karen Crum @vonburl]

@littoralpenguin @Daylight_Music Just donated. And really hope you are able to continue bringing music to everyone.

[Karen Crum @vonburl]

@keano81 This is brilliant

[Karen Crum @vonburl]

@cindygallop @makelovenotporn @Meta @wearehims @AvestriaVC @Forbes This is ridiculous. What’s their rationale for rejecting them?

[Veera Rajagopal  @doctorveera]

A mind-blowing paper has come out today in @Nature

In 2016, JC Venter Institute scientists trimmed a bacterial genome to its barest minimum required for life to synthesize what they called a "minimal genome" (https://t.co/Rk8oZJ0bUj).

Today, a group of scientists from Indiana University reports how that minimal genome evolved over 2000 generations in comparison to the non-minimal genome.

The authors found that even when you reduce a bacterial genome to its absolute minimum where every nucleotide matters, the genome undergoes mutational events generation after generation as much as the non-minimal genome. One simply cannot stop the evolution.

Just over 300 days of evolution (equivalent to 40,000 years in humans) the minimal cell has gained everything it lacked in fitness on day one in comparison to the non-minimal cell.

When comparing the evolved traits between the minimal and non-minimal cells, the scientists found something striking. The evolutionary process increased the cell size of non-minimal cells but not that of the minimal cell. But that is not the striking part.

The scientists were able to identify the key mutation that resulted in cell size evolution. And it turned out that the mutation that helped the non-minimal cells to grow bigger is the same that helped the minimal cells to stay smaller. Growing bigger had a survival advantage for non-minimal cells and not growing bigger had a survival advantage for minimal cells. So, the mutation had a context-dependent effect. This just demonstrates that the evolutionary effects on traits have no absolute direction. All that matter is what is beneficial for the organism's survival.

The conclusion of the paper is metaphorically a quote from the Jurassic Park movie:

“Listen, if there’s one thing the history of evolution has taught us is that life will not be contained. Life breaks free. It expands to new territories, and it crashes through barriers painfully, maybe even dangerously, but . . . life finds a way". (https://t.co/UlxRlb86CT)

https://t.co/zA9OAqSoAu

[Karen Crum @vonburl]

@nattergraeme @nilsleonard Congratulations - so good to see you all win ❤️

[Karen Crum @vonburl]

@Robertc1970 Yes, the last 2.5 mins of ‘Vomit’ by Girls song is something I adore more than song itself (and the song is brilliant, but the ending is breathtaking). https://t.co/L8nO6ktdzq
(As an aside, a very difficult song for SEO)

[Karen Crum @vonburl]

@mrsimonraymonde @julesbuckley @BBCSO @BarbicanCentre @fatherjohnmisty Just coming back home from it. It was incredible.

[Karen Crum @vonburl]

@ThatEricAlper John Prine and Iris DeMent doing ‘In Spite of Ourselves’