SUPER IMPRESSIVE: pancreatic cancer just got its most meaningful survival improvement
daraxonrasib vs chemotherapy:
- 13.2 months median survival vs 6.7 months
- 53% of patients alive at 12 months vs 17%
- hazard ratio 0.40. that means a 60% reduction in the risk of death
but here is what's even more impressive
RAS mutations drive 30% of all human cancers. lung, colon, pancreatic. the most common and the deadliest. RAS has been called undruggable for 40 years. Revolution Medicines just drugged it
an oral pill. once daily. FDA Breakthrough Therapy designation and it's being presented at ASCO this week
that is what happens when you combine precision genomics, targeted therapy design, and the audacity to go after the target everyone said was impossible
the era of cancer as a death sentence is soon ending
bio/acc
you think the Enhanced Games is just a sporting event for enhanced humans?
it's actually the opening ceremony of a new world order
the normalization campaign for human 2.0
- what if sex was more pleasurable?
- what if you could look better at 60 than you did at 30?
- what if you never got sick again
-what if your mind worked at a frequency most people never reach?
- what if happiness was not a mood but a baseline?
-what would happen if you took psychedelics before choosing who to marry, where to live, and what to do with your life
that is the actual conversation happening in Las Vegas tonight
a few days ago I sat down with Christian Angermayer, the man who put $100M into psychedelics before anyone else would touch it. the man behind ENHANCED GAMES.
link below
Vanity drugs make more money than AI.
Billionaire investor @C_Angermayer explains why peptides, GLP-1s, psychedelics, longevity & performance enhancement are exploding.
And why optimizing the human body and mind will become the next trillion-dollar industry.
0:00 - Human Enhancement Is Here
06:38 - Trans vs Looksmaxxing
11:12 - Enhanced Games
22:32 - Next Red Bull
25:48 - Going Too Far
32:18 - Psychedelics Unlock
37:49 - Universal Happiness
43:30 - MDMA x Marriage
46:27 - 12 vs 2h Trips
54:18 - Trump, Ibogaine, Addiction
1:00:22 - Sex, Pleasure, Female Orgasm
1:10:04 - Vanity Drugs & Future
>be me
>interview the Harvard professor
>ask about gene editing humans
>"we're already doing it"
>what about germline editing?
>"it's the cleaner solution"
>ask about modified humans walking among us
>"they're already here"
>how far away sir?
>"tomorrow"
>ask why we haven't
>[redacted]
>shift gears
>"US biotech losing to UAE?"
>he nods
>ask about the next dire wolf moment for humans
>"our ancestors wouldn't [redacted]"
>thank George, banger episode
>I post the episode on X
>algorithm nukes it
>cry
>WTF? link below
I interviewed @geochurch and learnt we're already gene editing humans. You just haven't noticed.
0:00 - Gene Editing Mammals → Humans
8:36 - Germline vs Somatic
14:56 - Modified Humans Are Already Here
18:50 - Enhancing Healthy Humans
25:00 - Aging Therapies vs Cognitive Enhancement
30:20 - Embryo Selection
38:10 - Is US Losing To UAE?
42:33 - Biotech Failures
49:31 - Next Dire Wolf Moment
54:21 - AI x Science
1:02:07 - Synthetizing Entire Genomes