Winter Jefferson

Second Life inhabitant, Glampire Extraordinaire. I keep forgetting about Twitter, and when I do tweet/retweet it's usually political... or narcissistic. He/Him

[Winter Jefferson @WinterJefferson]

@MarvelExrth616 I reckon it's Loki. Like he's there pre-God of Stories ascension to warn our crew of what's going to happen but can't resist being just a bit of a dick to Thor one last time.

[Winter Jefferson @WinterJefferson]

@NotAgnor It's bigger on the inside

[Winter Jefferson @WinterJefferson]

@daisiebird @KareemRevived Had my teeth clenched the whole way through

[Brooke from Let’s Not Date @TheLetsNotDate]

A man made a homophobic comment on my Facebook post about gay marriage. Turns out this man was a stunt actor. Perfect, because what came next was the role of a lifetime. 1/3

[Winter Jefferson @WinterJefferson]

@blackpegasus02 @theworld_ender Hughie would be so conflicted

[Anish Moonka @anishmoonka]

Toru Miyazaki gave 11 cats with advanced kidney disease an experimental injection. 15 others didn’t get it. A year later, 9 of the 11 treated cats were alive. Only 3 of the 15 untreated cats survived. He just filed for approval, and the drug fixes a defect only cats have.

Most cats die from one thing: their kidneys fail. By age 10, 4 in 10 cats already have chronic kidney disease, and by age 15, the rate doubles to 8 in 10. Once diagnosed, a cat has about 2 years left.

The reason kidney disease hits cats so hard is a broken protein in their blood. All mammals carry a protein that helps the kidneys clean out waste. In humans and dogs, the protein floats freely and goes to work when the kidneys are in trouble. In cats, it stays stuck to another protein and can’t get loose. So the waste piles up, and the kidneys eventually give out.

Miyazaki originally found the protein in 1999, back when he was at the University of Tokyo. He figured out the cat-specific glitch in 2015. The paper he published in the Veterinary Journal in February laid out the trial. The injection is a working version of the missing protein. His company, the Institute for AIM Medicine, filed the approval paperwork with Japan’s Ministry of Agriculture on April 24, 2026. If the review clears, the drug goes on sale in spring 2027.

The 30-year lifespan figure in the tweet is Miyazaki’s own projection of what cats could reach without kidney disease. The trial only ran a year, and the average cat today lives 15. Most die from the same disease this injection treats.

The research almost died in 2020. After running out of funding during COVID, Miyazaki went public. Cat owners across Japan responded by sending in 300 million yen, around 2 million dollars total. He resigned from the University of Tokyo and worked on the drug full time. The treatment in front of regulators today exists because cat lovers refused to let the research die.

[Winter Jefferson @WinterJefferson]

@trndytrndy @hoseokite First nine days were great! January 10th is when we lost the magic.

[Marvel Entertainment @Marvel]

love, persevering

[Winter Jefferson @WinterJefferson]

@Floweyfan314 @auminiii @neorouxls I've also seen DoritoBite used

[derek guy @dieworkwear]

One day, "It" will happen, by which I mean sudden and unexpected news that you want to celebrate. In such cases, you will want the right outfit. 🧵

[madoka magicock @rifflexielian]

If people are fighting for an orb you are reading fantasy. If people are fighting for a cube you are reading sci-fi. If it has more sides than that. I dont know. I dont know man.

[Winter Jefferson @WinterJefferson]

@Kirythegoat I would very much like you to finish this project also

[Winter Jefferson @WinterJefferson]

@s_unnihope Yay!

[Winter Jefferson @WinterJefferson]

@AmpelosWings @forever_gf618 Is he a twin? Or do we need to wait another year and a half to find out?

[Winter Jefferson @WinterJefferson]

@Ooh_Khamil Really, put some respect on the guy's name. Bill worked really hard on bringing about Weirdmaggedon, it's rude to not give him the credit.

[Winter Jefferson @WinterJefferson]

@FoxieSkullzArtz This is lovely

[Winter Jefferson @WinterJefferson]

@Pr0_0ddity @_AlexHirsch @bryan_johnson I think he let Bill reply to this one

[Winter Jefferson @WinterJefferson]

@orxinus You're obviously loved and valued by the right people then.

[Winter Jefferson @WinterJefferson]

@orxinus It's not surprising that you had a bad moment, looking at what you're going through. I think we are all just glad that you're okay.

[Winter Jefferson @WinterJefferson]

@orxinus Orxa are you okay?