Will Matlock

wellcome early-career award fellow @milnercentre | formerly @oxfordbiology and @modmedmicro

[Will Matlock @wtmatlock]

🚨 New preprint! 🚨 We reveal that blaTEM-1 expression varies across the E. coli phylogeny, driving differences in co-amoxiclav resistance: https://t.co/1FYxK0VZRl

[Tess Johnson @drtessjohnson.bsky.social @drtessjohnson]

Today my first editorial article came out! It's both an intro to my Monash Bioethics Review special issue on antimicrobial stewardship and social justice, and also an original article examining issues with the precautionary principle as a justification. https://t.co/yfejchSVFu

[Jose A Escudero @jaegc]

Finally out after peer review, our update on the integron model showing that translation rates of cassettes in first position influence the phenotypes conferred by others downstream.
Great effort by @AndrePCarvalho

https://t.co/f0j1LreGOU

[Will Matlock @wtmatlock]

@jaegc @AndrePCarvalho Wahoo! Congrats!

[Will Matlock @wtmatlock]

@JaviF_86 I hope it was interesting ☺️

[Will Matlock @wtmatlock]

@bbielggarcies11 Thank you!

[Will Matlock @wtmatlock]

So exciting to see our (Liam Shaw, @Sheppard_Lab, @EpicFeil_) piece on the current state of plasmid epidemiology is now out:

https://t.co/kJvLnflYWr

@NDMOxford @OxfordBiology @IneosOxford @MilnerCentre

[Will Matlock @wtmatlock]

Thanks for reading and let me know if you have any questions! (10/10)

[Will Matlock @wtmatlock]

A thread on our study… (1/10)

[Will Matlock @wtmatlock]

🚨 New preprint! 🚨 We reveal that blaTEM-1 expression varies across the E. coli phylogeny, driving differences in co-amoxiclav resistance: https://t.co/1FYxK0VZRl

[Will Matlock @wtmatlock]

2) How can we routinely incorporate phylogenetic information into AMR phenotype prediction? Hybrid assemblies are not always possible, so we need shortcuts. (9/10)

[Will Matlock @wtmatlock]

@gushamilton Thanks! DM me if anything isn’t clear 😊

[Will Matlock @wtmatlock]

🚨 New preprint! 🚨 We reveal that blaTEM-1 expression varies across the E. coli phylogeny, driving differences in co-amoxiclav resistance: https://t.co/1FYxK0VZRl

[bioRxiv Microbiology @biorxiv_micrbio]

E. coli phylogeny drives co-amoxiclav resistance through variable expression of blaTEM-1 https://t.co/pceFqEHXSx #biorxiv_micrbio

[Richard Neher @richardneher]

Ever wondered how fast accessory genome dynamics of bacteria really is?

In a new preprint we (@mrcmolari, Liam Shaw) explore how rapidly E coli picks up genes horizontally, breaks genome synteny, etc..

https://t.co/2msWt4c1z3

For a thread by Marco see
https://t.co/g0sr48eksf