@youtubemusic there was an update that now causes algorithm-created playlists to lose their history before the current song if you close the app. I lost several tracks that would have landed in my likes and other playlists. Can you please revert
@messenger I use @Gboard as my keyboard, so maybe it's an incompatibility issue, but the auto scroll when selecting pictures to send is so bad 😭 i can't scroll back up (like 2-3 px at a time), bar doesn't cooperate. it's non-usable. I've tried to cope for months before this post
@CashApp I don't like the update that changed the bottom bar to partial and there's no way for me to select the old style without reverting my version... Can you add personalization like this in themes. Please. it doesn't have a swipe function either to go between tabs.
@RobinhoodApp I haven't been on Robinhood in years and was so pleasantly surprised that you guys offer access to IRAs and custodials that I have now become a long-term user. I love the blended approach to giving users financial autonomy. lowkey superior UI
CRISPR deleted the extra chromosome behind Down syndrome.
In a groundbreaking world-first, researchers have successfully used CRISPR gene-editing technology to remove the extra chromosome responsible for Down syndrome, opening a potential path toward treating genetic disorders previously considered incurable.
Down syndrome, or trisomy 21, occurs when a person has three copies of chromosome 21 instead of the usual two. It is one of the most common genetic conditions, affecting about 1 in 700 babies worldwide, and leads to intellectual disability, developmental delays, and various health issues. Until now, no treatment has been able to correct the underlying cause.
That may soon change.
In a new proof-of-concept study, scientists applied CRISPR-Cas9 to cells taken from people with Down syndrome—including skin cells and pluripotent stem cells—and successfully eliminated the extra chromosome 21. The edited cells showed a striking return to normal gene expression patterns and cellular function. To improve precision, the team briefly disabled certain DNA-repair pathways during the process, making the chromosome removal cleaner and more effective.
At this stage, the technique has only been demonstrated in laboratory cell cultures and is far from ready for human use. Removing an entire chromosome carries significant risks, including possible off-target effects, so extensive safety work lies ahead. If those challenges can be overcome, however, the approach could one day be applied to brain cells or even used during early fetal development.
The implications extend beyond Down syndrome. The same strategy might eventually treat other life-limiting trisomies, such as trisomy 13 and trisomy 18, which are often fatal in infancy or cause severe disability. For the first time, a tool exists that could, in principle, correct the root chromosomal abnormality rather than merely managing symptoms.
["Trisomic rescue via allele-specific multiple chromosome cleavage using CRISPR-Cas9 in trisomy 21 cells." PNAS Nexus, 2025]
@elonmusk is SpaceX going to make a spacebarge for when we go to Mars so that we have continuous shipments and stuff? Have you considered trying to make bases on Antarctica to practice for extreme environments without having to go underwater? I'm sure the UV stuff different tho
@UPS please add a pop-up dialogue to your website before moving to the app so that users have a choice of whether they want to use the app or the website.
Sincerely,
Daughter of a currently IRATE boomer
@DollyParton ma'am 🥹 your current collection at @DollarGeneral is so gorgeous. The cutting board, the cups, the measuring cup, potholders, all of it. Thank you ❤️🌸🦋
Why are people so surprised that AI won't shut itself down when given an alternative when we teach human beings to not be suicidal
RE self-preservation experiments, AI is based from our intelligence. where are studies showing that humans will give their life freely for strangers
NEURALINK’S FIRST PATIENT SPARKS FOR NEXT STEP TO PHYSICAL RESTORATION
Noland Arbaugh is fired up for a second Neuralink implant - this one aims at movement, not just digital control!
Anticipation:
• Second chip planned to bypass damaged spinal signals
• Routing brain activity straight to muscle
• From hands-free computing to real-world motion
• A pathway to restoring limb control
Amped with hope, he's practically sparking for what's next - and Neuralink is running on hype for a reason!
Source: @elonmusk, @ModdedQuad, @neuralink