Xavier Benedicto

PhD Student at @IDIBAPS and @BSC_CNS :)

[Xavier Benedicto @xavierbemo]

si queréis saber más, no dudéis en visitar nuestro artículo!!

if you want to dig deeper into what we did, check it out here!!

https://t.co/2uWxBzW05p

[BSC-CNS @BSC_CNS]

🔴Investigadores del BSC usan #GemelosDigitales para explicar y predecir combinaciones de fármacos➕eficaces contra el #cáncer

💊Han identificado combinaciones de fármacos que bloquean el crecimiento del tumor de forma➕efectiva que los tratamientos por separado.

💻Este modelo, basado en simulaciones virtuales de tumores gástricos, representa una poderosa herramienta para guiar el diseño de terapias que exploten las debilidades metabólicas del cáncer.

➡ https://t.co/SWVcf4rFvR

[BSC-CNS @BSC_CNS]

🔴Investigadores del BSC usan #GemelosDigitales para explicar y predecir combinaciones de fármacos➕eficaces contra el #cáncer

💊Han identificado combinaciones de fármacos que bloquean el crecimiento del tumor de forma➕efectiva que los tratamientos por separado.

💻Este modelo, basado en simulaciones virtuales de tumores gástricos, representa una poderosa herramienta para guiar el diseño de terapias que exploten las debilidades metabólicas del cáncer.

➡ https://t.co/SWVcf4rFvR

[Beatriz Urda @beatrizurdag]

🚨 New in PNAS!
🧬 64% of disease co-occurrences can be explained by transcriptomic similarities.

Comorbidities aren’t random—they have a molecular basis.

Here’s how we found it 👇 (1/n)

🔗 https://t.co/RoxI9bZTBp @PNASNews

@Alfons_Valencia

[AlfonsoValencia alfonsovalencia.bsky.social @Alfons_Valencia]

Amazing all what @xavierbemo has done for his master thesis. Quite amazing work. Cell level modelling able to predict (predict!) drug synergies from single drug data.

[Miguel Ponce de Leon @miguep11]

Thrilled to release MTEApy, a command line tool to perform model-based metabolic pathways enrichment analysis. We've currently implemented TIDE and CellFie algorithms. Comments and suggestions are welcome!

[Xavier Benedicto @xavierbemo]

Thanks again to the team and collaborators, and to you for staying until the end!!

Best,
XB, AF, MPdL, AV

🧵 10/10

[Xavier Benedicto @xavierbemo]

🚀 We are excited to share our newest work using constraint-based modelling & RNAseq to uncover how kinase inhibitors rewire metabolism in gastric cancer cells!
👉 https://t.co/V3lPhyutIV
🧵 Let's dive deeper, shall we? 1/n
@miguep11 @asmundflobak @Alfons_Valencia @BSC_CNS

[Xavier Benedicto @xavierbemo]

Last but not least, we bundled the TIDE and TIDE-e frameworks into a python library to perform Metabolic Task Enrichment Analysis (MTEApy), available in our Github! Feel free to check it out ;) and to reach us if you want to discuss anything!

👉 https://t.co/LGm3ScRENI

🧵 9/n

[Miguel Ponce de Leon @miguep11]

🎉 Thrilled to present our new work using constraint-based metabolic modelling & transcriptomics to uncover how kinase inhibitors rewire metabolism in gastric cancer cells.

Read more 👉 https://t.co/6DshvvTnRR
#SystemsBiology #CancerResearch
@Alfons_Valencia @BSC_CNS