Xavier Dole

[Xavier Dole @xavierdole]

The difference between utopia and dystopia is financial engineering.

[Simon Maechling @simonmaechling]

Saying “I don’t need experts, I think for myself” is like saying “I don’t need a map, I have confidence.

[Simon Maechling @simonmaechling]

@RIPBrotherDavid RIP, Brother David.

[Xavier Dole @xavierdole]

@simonmaechling I don’t think that’s enough. My impression is that basically literacy, from high school, isn’t enough without critical thinking (assessing methodologies, fallacies, etc)

[Xavier Dole @xavierdole]

@LovingMY_Aniya Yes but for social impact bonds the risk to reward ratio is not favorable for investors. There is far more incentive for politicians than investors currently.

[Xavier Dole @xavierdole]

@theWhyteClan @ClareONeilMP Whats wrong with social impact bonds?

[Xavier Dole @xavierdole]

@DanielHayes31 @kacdnp91 Social impact bonds have the potential to be something truly positive for humanity

[Xavier Dole @xavierdole]

@theWhyteClan @deemadigan Would you care to expand on your opinions on social impact bonds?

[Xavier Dole @xavierdole]

@simonmaechling All problems and solutions are a downstream result of the education system.

[Xavier Dole @xavierdole]

@salkhanacademy I was wondering if I could present an idea to someone at Khan Academy. I believe I’ve discovered a new lens for Khan Academy that could generate a massive uptick in revenue — without increasing donations, compromising data privacy, or putting education behind a paywall.

[Kevin C. Klatt, PhD, RD @KCKlatt]

There's lots of rhetoric lately about the poor state of nutrition & chronic disease in the USA that flies in the face of several realities:

1 - Nutrition is much harder to study than drugs yet we have minimally invested in nutrition research seriously. It is disjointedly tackled via NIH & USDA and it doesn't have a pharma industry to fund much needed trials. Funding has only gotten worse in the past 2 decades with the switch from the GCRC to CTSI model. Most nutrition initiatives will suffer from limited high quality evidence backing them.

2 - Where we do have solid evidence, there has rarely been the political will to take action. Regulation has long been mocked as nanny state tactics (see responses to Michelle Obama efforts) or been subject to merchants of doubt-type efforts (see Sodium post 2015 DGAs). We've never seen serious investment in lifestyle programs despite decades since Landmark trials like the DPP. We don't see reimbursement for dietitian & other lifestyle services.

3 - the 'F' in FDA has been chronically underfunded. It doesn't have the staff, doesn't get user fees, and is tasked with everything from foodborne illness to contaminants and chronic disease.

Political actors (eg @calleymeans) are painting the failures of some imagined nutrition establishment who've drowned in resources and have failed the American people, even throwing solid researchers like @KevinH_PhD under the bus as if they had any power to change the above. This anti-establishment narrative is convenient but unserious. It may line the pocket of the personal businesses of administration members but history will judge it harshly for being so unserious and squandering serious cultural capital to take action on nutrition & chronic disease.

[Simon Maechling @simonmaechling]

No chemical is inherently good or bad.

It depends on how it’s used, how much, and in what situation.

[Ben Stinar @BenStinar]

RESPECT TO EVAN MOBLEY

BUT NO ONE WAS A BETTER DEFENDER IN 2025 THAN DYSON DANIELS 🔒

[Xavier Dole @xavierdole]

@tsarnick What brand Tshirt is he wearing? Where can I buy it?

[Xavier Dole @xavierdole]

@brave Brave is awesome.

[Xavier Dole @xavierdole]

@dr1337 @michaelfrazis Primary school students don’t get assigned homework anymore. Although, regarding ChatGPT that is the case in high schools. Nowadays an effective means is to market their homework to them through concepts like opportunity cost.

[Xavier Dole @xavierdole]

@kevinnbass Can I ask what was the methodology behind this study? As to my understanding we are not able to accurately measure serotonin through blood. It would be interesting if you elaborated on this conclusion you have come to.

[Xavier Dole @xavierdole]

@dr1337 @michaelfrazis [Trying to make kids interested in STEM]

Me:
“The number of lives we have saved from GMOs is over 1 billion. If we made a video where one person equaled one second, that video would go for over 32 years.”

The student:
“Have you played the new Lego Fortnite update?”

[Xavier Dole @xavierdole]

@dr1337 @michaelfrazis There isn’t a lot in their environment to inspire them to be interested in STEM. I work in a primary school and it is very difficult to make kids interested in STEM.

[Xavier Dole @xavierdole]

@dr1337 @michaelfrazis [Trying to make kids interested in STEM]

Me:
“The number of lives we have saved from GMOs is over 1 billion. If we made a video where one person equaled one second, that video would go for over 32 years.”

The student:
“Have you played the new Lego Fortnite update?”