Oscar Yanes

Biochemist. Coordinator @ciberdem @IISPereVirgili #Metabolomics Platform. Assistant Prof @etseURV. Affiliated member @IRBBarcelona. Former @scrippsresearch

[Oscar Yanes @yaneslab]

go to #BlueskySocial #BlueSky to see a thread https://t.co/eO474njKdb

[Oscar Yanes @yaneslab]

We’re excited to share our latest work "Improving MALDI Mass Spectrometry Imaging Performance: Low-Temperature Thermal Evaporation for Controlled Matrix Deposition and Improved Image Quality" | Journal of the American Society for Mass Spectrometry https://t.co/osES2hkvFD 🧵👇

[Oscar Yanes @yaneslab]

Delighted and honored to have participated in this fascinating study led by @ManelEsteller

[Manel Esteller @ManelEsteller]

Excited to share our #multiomics study of who was the world's #oldest living person! Our research on this record-breaking #supercentenarian suggests that, under certain conditions, #aging and #disease can become decoupled—challenging the common belief that they are inherently linked. #longevity #science Enjoy!
https://t.co/SN1Bavv40x

[Marcus Buschbeck and Lab @MarcusBuschbeck]

ONLY 3 DAYS LEFT for computational biologists ...!

To apply for a PhD position
- on Metabolic Genome Regulation
- in Acute Myeloid Leukemia
- supervised by @tvavouri and me
- at @carrerasIJC
- in Barcelona, Spain
- part of @MSCActions HubMOL

https://t.co/CKPH0Snhhg

Please RT!

[Oscar Yanes @yaneslab]

5/ Want to learn more? 📄 Read our full paper on #bioRxiv: https://t.co/0HdEuHz89h
#Metabolomics #MachineLearning #DeepLearning #MSMS We’d love to hear your thoughts!
This is another successful collaboration with @sees_lab at @universitatURV

[Oscar Yanes @yaneslab]

🚀 New paper alert! 🚀 Happy to introduce #ChemEmbed, a deep learning framework for metabolite identification that enhances MS/MS data and leverages multidimensional molecular embeddings. A 🧵 on how it works ⬇️ #metabolomics #MachineLearning #DeepLearning

[Oscar Yanes @yaneslab]

4/ The results:
✅ ChemEmbed ranks the correct metabolite #1 in 42% of cases in a test dataset.
✅ Finds the correct compound in the top 5 in 76% of cases
✅ Against external benchmarks CASMI 2016/2022, and ARUS dataset (human plasma & urine), ChemEmbed outperforms #sirius 6

[Oscar Yanes @yaneslab]

I finally moved to #BlueSky #BlueskySocial Kind of funny to add this in X, but I'll end up quitting this platform. Here's my profile in BlueSky for those interested : https://t.co/LYp0I56j9g

[Oscar Yanes @yaneslab]

An ongoing study in our lab focuses on developing new matrices for MALDI-MSI of small molecules (m/z <400) using LTE deposition. We're minimizing matrix background interference while enhancing metabolite ionization and coverage, paving the way for #Spatial #Metabolomics

[Oscar Yanes @yaneslab]

🚀 Excited to share our latest study on a novel approach for #MALDI-#MSI matrix deposition! We’ve developed a low-temperature thermal evaporation (LTE) method that optimizes sensitivity, spatial resolution, and reproducibility. 🧵

[Oscar Yanes @yaneslab]

🔬 Read more about how LTE advances the field of MALDI-MSI, including crystal morphology, stability tests, and comparative analysis with spray-coating, in our new preprint: https://t.co/Ru9MXUsnZG #MALDIMS #MassSpectrometry #Lipidomics

[Valentina Ramponi @ValentinaRampo5]

I am thrilled to finally share our work on persister cancer cells: we identify distinctive features and actionable #vulnerabilities ⚡️of persister cancer cells (#DTP), and provide mechanistic insight into their low #inflammatory activity:
https://t.co/hf5gHbmtq0

👩‍🔬🧪🔎 ⬇️

[Oscar Yanes @yaneslab]

Mai oblidaré el teu bon tracte i la confiança que vas dipositar en mi. Joan, sempre t'estaré agraït. DEP 🫶🏼

[IRB Barcelona @IRBBarcelona]

Amb profunda tristesa, lamentem comunicar la mort aquesta passada matinada del Dr. Joan Guinovart, fundador, exdirector, exinvestigador i professor emèrit de l’IRB Barcelona.

El Dr. Guinovart ha estat una figura clau en l’àmbit de la bioquímica, deixant una empremta inesborrable tant a nivell científic com de gestió. La seva intel.ligència, lideratge i el seu profund humanisme han estat fonamentals per a les persones que hem tingut la sort de compartir camí amb aquest home irrepetible i per al món de la recerca.

Expressem el nostre més sentit condol a la seva família, amics, companys i a tota la comunitat de l'IRB Barcelona.

Joan, la teva absència ens deixa un gran buit, però el teu llegat perdurarà per sempre.

Et recordarem sempre, capità.