jesse gray

team-builder, scientist. genomics. neurogenetics. RNA biology.

[jesse gray @yargessej]

If you're a neurogenomicist in Seattle with mad computational chops + interested in working for the @AllenInstitute LMK. Cool gig.

[Steve McCarroll @s_mccarroll]

Excited to share this discovery: Huntington's disease is a DNA process for almost all of a cell's life. Inherited HD alleles are innocuous, just unstable – CAG repeats slowy expand throughout life, acquiring toxicity only when quite long (>150 CAGs). https://t.co/6wIAZKCWKN

[jesse gray @yargessej]

Team leads for different aspects of genome recording

Scientist & team lead for sensing biological signals
https://t.co/QwpWQuBRLX
Scientist & team lead for writing to DNA
https://t.co/LP7MfsYHGd
Scientist & team lead for reading from DNA
https://t.co/PkPlhQQOJS

(4/4)

[jesse gray @yargessej]

Exciting! Seven awesome new scientist & operations roles in my new hometown of #Seattle #Biotech #TheEcoSystem!
"Reimagine living cells and genomes as devices for recording biology and diagnostic information over time, as well as for encoding real-time decision-making."
(1/4)

[jesse gray @yargessej]

Large scale DNA synthesis

Research Associate Scientist
https://t.co/ZZ6dZPmbsa
Scientist
https://t.co/9cxydNwnBB

(3/4)

[jesse gray @yargessej]

The actions of @aga_naturalgas do not align with the values of @PGE4Me @PatriciaPoppe3. As trusted partners in the transition to healthy homes & buildings, 20 orgs are calling on PG&E leave AGA & stop funding climate obstruction.
https://t.co/IgOlKyGJba

[Jan Rosenow @janrosenow]

7/ I'm not aware of other countries putting in place mandates for hydrogen-ready boilers. Instead they increasingly tend to set end-dates for gas boilers to be installed.

[Jan Rosenow @janrosenow]

Fossil gas is a dead-end road.

For a long time, gas has been seen as a bridge from coal on the road to net-zero.

Not anymore. A hard-hitting report from the prestigious European Academies of Science @EASACnews makes the case to phase out fossil gas for good.

🧵

[John VanScoyoc @JohnVanScoyoc]

Vote on May 2 like the future depends on it. Thank you, Climate Forward Brookline, for endorsing my re-election to the Select Board!

[Jan Rosenow @janrosenow]

This is huge: Yesterday the German government confirmed plans to no longer allow stand-alone fossil fuel heating systems to be installed from 01 January 2024.

That’s in all buildings and will come into force in just 8 months.

https://t.co/MuRR2nWxXj

[jesse gray @yargessej]

This is a well-deserved award for one of the best scientists, mentors, and human beings on this planet. From the discovery of immediate early gene induction in cultured cells to how IEGs support learning in the hippocampus— quite a journey!

https://t.co/6GV54HlueE

[jesse gray @yargessej]

@drugmonkeyblog There are some sympathetic comments here. But ‘the lost decade’ in human genetics seems like a case of a field — under the usual academic pressure — publishing what can be published rather than what’s compelling.

It wasn’t compelling science at the time.

[jesse gray @yargessej]

Then I asked it to provide references. As usual, it seems to have made them up from whole cloth.

It seems to make up titles, attach valid DOIs from unrelated articles, make up the authors, and choose reasonable sounding real journal names.

Does this mean the facts are wrong?

[jesse gray @yargessej]

I asked chatGPT4 which AAV serotypes when administered systemically transduce skin.

The answer seemed very reasonable on the face of it, and maybe it’s accurate.

[Angelos Georgakis @angelosgeo]

Bench scientist to biotech CEO is a brutal transition.

6 key mindset shifts for the biotech leaders of tomorrow:

[jesse gray @yargessej]

Team dynamics are rate-limiting in every ambitious human enterprise.

“…fundamental issues with the dynamic of this group that resulted in an inability to work collaboratively and productively, impeding the standards-setting process.”

https://t.co/r9ubqmPUxf

[jesse gray @yargessej]

One of the great pleasures of industry is academic voyeurism (and recruiting) at conferences.

Nearly three years out of @harvardmed — and in @AscidianTx — I couldn’t be happier, or more exited to be headed back to #SfN22!

[jesse gray @yargessej]

Exciting day. Ascidian Therapeutics rewrites RNA. Enabling gene therapy to be applied to genes that don’t fit in AAV. https://t.co/nrCoxpDSCJ

[Jake M. Grumbach @JakeMGrumbach]

this is a slap in the face to everyone who worked hard and paid the $51 to Elsevier to rent an article for 24 hours