Alessandro Piccin

Neuroscientist @univca | Neuromodulation and (mal)adaptive behaviour | Sonic correspondent @impattosonoro | 🇸🇪🇫🇷🇮🇹🇪🇺

[Alessandro Piccin @yeahtoastz]

Very proud to share our most recent work, now out in @CellReports. 🎉

We show that brief #locuscoeruleus noradrenergic signals in the #orbitofrontalcortex, triggered by surprising rewards, support reversal learning and predict how quickly animals adapt.

https://t.co/XGX8vuw7Qt

[Alessandro Piccin @yeahtoastz]

ALBUM OF THE WEEK: "Little Wide Open" di @kevinmorby, un’ode intima e ostinata alla sua terra (il Midwest) e alla suo essere americano. Prodotto da @aaron_dessner (The National) per @DeadOceans. #americana #folk https://t.co/r5AbezIYrt

[tommaso patriarchi @tpatriarchi]

Wait… localized norepinephrine transients in the awake visual cortex?!
Who would have guessed this neuromodulatory signal is that spatially precise, right where visual processing is happening. Brain state control just got a lot more local. https://t.co/e4OGR9dlTB

[Ginevra D'Ottavio @ginevradottavio]

New preprint from @yavinshaham lab.

Using FDG-PET in rats, we show that heroin self-administration and addiction vulnerability are associated with specific whole-brain metabolic alterations, without impairments in social reward processing.

[RaffaellaTonini@ IIT Neuromodulation @RaffaellaTonini]

Happy to share the latest published study from the lab!!

https://t.co/Y1niSGl3jI

[Alessandro Piccin @yeahtoastz]

Most exciting project I’ve worked on so far. A real #DECAD team effort alongside @HadrienPlat, @YacineTensaouti, Mathieu Wolff, Alain Marchand & Etienne Coutureau. Grateful to @Neuro_Bordeaux, @univbordeaux_EN, @AgenceRecherche and @BBRFoundation for supporting this work. 🙏

[Alessandro Piccin @yeahtoastz]

Very proud to share our most recent work, now out in @CellReports. 🎉

We show that brief #locuscoeruleus noradrenergic signals in the #orbitofrontalcortex, triggered by surprising rewards, support reversal learning and predict how quickly animals adapt.

https://t.co/XGX8vuw7Qt

[Alessandro Piccin @yeahtoastz]

@fornari_claudia @steph_daumas @fgeorges007bnst @FuschiaSerre @anna_beyeler @CelineNicolas2 @chloe_arrondeau Congratulazioni Claudia!! 🥳

[Alessandro Piccin @yeahtoastz]

It's official! I've been awarded an #MSCA Postdoctoral Fellowship to work at @univca w/ Miriam Melis 🏖️🇮🇹

SPICE-FONTS will investigate the role of #noradrenaline in neurodevelopmental deficits caused by prenatal #cannabis exposure 🤰🌿

Grateful @MSCActions @EU_Commission 🙏🇪🇺

[Alessandro Piccin @yeahtoastz]

Despite the translational failure of CRF1 receptor antagonists (see https://t.co/OnPqXMpOrh), these results show how some of these compounds might find new life in treating opioid-induced social deficits, which are known for worsening the clinical outcome of opioid use disorders.

[Alessandro Piccin @yeahtoastz]

Let's just say that when these experiments took place I had no idea where Wuhan was or how to change a diaper. So, you can just imagine how relieved I am to see this work out! A smooth and positive experience with the new @eLife model, which I recommend. https://t.co/pPJBFy0nWh

[Alessandro Piccin @yeahtoastz]

At last, we show that, in male mice, antalarmin abolishes morphine-induced firing in neurons co-expressing OXY and AVP, but not in neurons expressing only AVP, thereby suggesting a sex-dependent mechanism of action involving CRF1 receptors and oxytocinergic neurons of the PVN.

[Yacine Tensaouti, PhD ⵣ @YacineTensaouti]

Successfully defended my PhD thesis: 'Contribution of the rat insular cortex to stimulus-guided action.' Grateful to my supervisor @ShaunaParkes, my thesis committee, and all my lab mates who made this work possible! 🎉🍾🔬🐀 #DECAD @inciabordeaux

[Yacine Tensaouti, PhD ⵣ @YacineTensaouti]

🧬Excited to share a piece of my PhD work now available on bioRxiv!

With Louis Morel and @ShaunaParkes, we investigated how the rat insular cortex contributes to stimulus-guided action.

Read on to find out more!🧵👇🏻
#Neuroscience #PIT #InsularCortex #DecisionMaking

[Alessandro Piccin @yeahtoastz]

@vgarciarivas Looks awesome! Have fun guys ❤️

[Alessandro Piccin @yeahtoastz]

@CelineNicolas2 @CNRS @Neuro_Bordeaux Congrats Céline! What a year! 🎉🎉🎉

[Alessandro Piccin @yeahtoastz]

The last piece of work from my PhD is finally available on bioRxiv! We show how disrupting the #CRF/#CRF1 receptor pathway sex-dependently eliminates #morphine-induced #sociability deficits and abnormal firing of #PVN #oxytocin neurons in mice.
https://t.co/7f03lnT7ia