Very proud to share our most recent work, now out in @CellReports. 🎉
We show that brief #locuscoeruleus noradrenergic signals in the #orbitofrontalcortex, triggered by surprising rewards, support reversal learning and predict how quickly animals adapt.
https://t.co/XGX8vuw7Qt
ALBUM OF THE WEEK: "Little Wide Open" di @kevinmorby, un’ode intima e ostinata alla sua terra (il Midwest) e alla suo essere americano. Prodotto da @aaron_dessner (The National) per @DeadOceans. #americana#folk https://t.co/r5AbezIYrt
Wait… localized norepinephrine transients in the awake visual cortex?!
Who would have guessed this neuromodulatory signal is that spatially precise, right where visual processing is happening. Brain state control just got a lot more local. https://t.co/e4OGR9dlTB
New preprint from @yavinshaham lab.
Using FDG-PET in rats, we show that heroin self-administration and addiction vulnerability are associated with specific whole-brain metabolic alterations, without impairments in social reward processing.
Very proud to share our most recent work, now out in @CellReports. 🎉
We show that brief #locuscoeruleus noradrenergic signals in the #orbitofrontalcortex, triggered by surprising rewards, support reversal learning and predict how quickly animals adapt.
https://t.co/XGX8vuw7Qt
It's official! I've been awarded an #MSCA Postdoctoral Fellowship to work at @univca w/ Miriam Melis 🏖️🇮🇹
SPICE-FONTS will investigate the role of #noradrenaline in neurodevelopmental deficits caused by prenatal #cannabis exposure 🤰🌿
Grateful @MSCActions @EU_Commission 🙏🇪🇺
Despite the translational failure of CRF1 receptor antagonists (see https://t.co/OnPqXMpOrh), these results show how some of these compounds might find new life in treating opioid-induced social deficits, which are known for worsening the clinical outcome of opioid use disorders.
Let's just say that when these experiments took place I had no idea where Wuhan was or how to change a diaper. So, you can just imagine how relieved I am to see this work out! A smooth and positive experience with the new @eLife model, which I recommend. https://t.co/pPJBFy0nWh
At last, we show that, in male mice, antalarmin abolishes morphine-induced firing in neurons co-expressing OXY and AVP, but not in neurons expressing only AVP, thereby suggesting a sex-dependent mechanism of action involving CRF1 receptors and oxytocinergic neurons of the PVN.
Successfully defended my PhD thesis: 'Contribution of the rat insular cortex to stimulus-guided action.' Grateful to my supervisor @ShaunaParkes, my thesis committee, and all my lab mates who made this work possible! 🎉🍾🔬🐀 #DECAD @inciabordeaux
🧬Excited to share a piece of my PhD work now available on bioRxiv!
With Louis Morel and @ShaunaParkes, we investigated how the rat insular cortex contributes to stimulus-guided action.
Read on to find out more!🧵👇🏻
#Neuroscience#PIT#InsularCortex#DecisionMaking
The last piece of work from my PhD is finally available on bioRxiv! We show how disrupting the #CRF/#CRF1 receptor pathway sex-dependently eliminates #morphine-induced #sociability deficits and abnormal firing of #PVN#oxytocin neurons in mice.
https://t.co/7f03lnT7ia