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Public Health, Technology, Nutrition, Good Governance.๐ท๐ด
This table summarizes NICE recommendations for using SGLT2 inhibitors (Empagliflozin, Dapagliflozin, Canagliflozin, Ertugliflozin) for type 2 diabetes management.
https://t.co/leOBekr5J6
Most people treat wisdom teeth like an inconvenience. Something that grows in wrong, causes pain, and gets thrown away. Recent research suggests we may have been discarding something far more valuable than anyone realized.
Wisdom teeth contain mesenchymal stem cells inside their dental pulp, the soft living tissue at the core of the tooth. These are not ordinary cells. Stem cells are the body's raw material, capable of transforming into many different types of specialized tissue. And the ones found in wisdom teeth are remarkably versatile.
Studies have shown these cells can develop into cardiac muscle cells to help repair heart tissue after a heart attack. They can become neural cells, opening possibilities for stroke recovery and diseases like Parkinson's. They can also become bone and cartilage for skeletal repair.
What makes wisdom teeth especially valuable is the timing. They are removed between ages 17 and 25, exactly when stem cells are at their most potent and adaptable. Young stem cells survive longer, respond better, and integrate more effectively into damaged tissue.
And unlike embryonic stem cells which carry ethical controversy, dental stem cells come from tissue that was already being removed. No extra procedures. No ethical complications. Just a resource we have been throwing in a medical waste bin for decades.
There are now companies that will cryogenically preserve your wisdom teeth stem cells at extraction, the same way parents bank umbilical cord blood at birth.
The science is still developing. But the research is serious and growing fast.
It turns out the tooth your dentist pulled when you were a teenager may have contained the seeds of your own biological repair kit.
From the surface of the Moon, Earth appears as a bright and beautiful sphere our home floating in the vast darkness of space. Every ocean, continent, and form exists on that distant blue world. The contrast between the Moon's silent, grey landscape and Earth's vibrant colors makes this view truly powerful. It reminds us how special and unique our planet is. Standing on another world and looking back at Earth changes perspective everything we know is contained in that small glowing sphere.
A distant view... but still home
PhD Students - Here are the 8 types of research gaps you must know.
1. ๐๐ง๐จ๐ฐ๐ฅ๐๐๐ ๐ ๐๐๐ฉ
โณ There is no or limited research on your topic.
2. ๐๐ฏ๐ข๐๐๐ง๐๐ ๐๐๐ฉ
โณ Your research contradicts existing research
3. ๐๐๐ญ๐ก๐จ๐๐จ๐ฅ๐จ๐ ๐ข๐๐๐ฅ ๐๐๐ฉ
โณ The existing research methods for your topic are insufficient.
4. ๐๐ฆ๐ฉ๐ข๐ซ๐ข๐๐๐ฅ ๐๐๐ฉ
โณ There is no or limited empirical data for your research topic.
5. ๐๐ซ๐๐๐ญ๐ข๐๐๐ฅ ๐๐ง๐จ๐ฐ๐ฅ๐๐๐ ๐ ๐๐๐ฉ
โณ There is a disconnect between theory and practice in your topic.
6. ๐๐ก๐๐จ๐ซ๐๐ญ๐ข๐๐๐ฅ ๐๐๐ฉ
โณ Theoretical explanation for your topic is inadequate.
7. ๐๐จ๐ฉ๐ฎ๐ฅ๐๐ญ๐ข๐จ๐ง ๐๐๐ฉ
โณ Population is not fully or correctly represented in existing research.
8. ๐๐๐ญ๐ ๐๐๐ฉ
โณ The existing data is insufficient to address the research question.
Si Trump s'en prenait aux infrastructures รฉnergรฉtiques critiques de l'Iran comme les centrales รฉlectriques et les raffineries, alors ce cas il s'รฉcarterait totalement de ses objectifs de guerre qui รฉtaient d'anรฉantir les capacitรฉs militaires iraniennes.
Orforglipron: The Oral GLP-1 Era Has Truly Begun
By Dr Firdous Shaikh, Mumbai
๐น Orforglipron (Foundayoโข) is now the first FDA-approved once-daily oral nonpeptide GLP-1 receptor agonist, marking a major shift for patients who prefer effective metabolic therapy without injections.
๐น In type 2 diabetes, the ACHIEVE-3 trial showed superior HbA1c reduction and greater weight loss versus oral semaglutide, positioning orforglipron as a potentially powerful oral incretin option.
๐น Its benefits appear to extend beyond glucose lowering, with improvements also seen in body weight, systolic blood pressure, and lipid/triglyceride parameters, reinforcing its cardiometabolic relevance.
๐น In the ATTAIN obesity program, orforglipron delivered substantial weight loss (up to 14.7%), highlighting its emerging role not only in diabetes but also in obesity management.
๐น The biggest practical advantage is ease of useโa once-daily pill without food/water timing restrictionsโalthough clinicians must remain vigilant for GI adverse effects, discontinuation risk, and pulse rate increase, consistent with the GLP-1 class effect.
Bottom Line
Orforglipron may become a major disruptor in diabetes and obesity careโbringing potent GLP-1 efficacy into a far more acceptable oral format for real-world patients.
Glucometer devices aren't as precise as hospital lab machines. The ISO 15197:2013 standard dictates exactly how accurate these home glucometers must be to be sold and used safely.
The main rule is simple. If your blood sugar is below 100 mg/dL, the meter reading should be no more than 15 points higher or lower than the real value (at least 95% of the time).
If it's 100 or higher, the reading should be within 15% of the true number (again, 95% of readings).
For example, if true blood sugar is 105, a good meter could show anywhere from about 89 to 121 and still pass. They test this using three different batches of test strips. There's also a safety check. Almost all results (99%) must be safe enough that they wouldn't cause a person to make a dangerous decision about insulin or food.
This standard exists because tiny differences are normal due to how the strips work, temperature, how you use it, etc. In the video, the meters showed 100 to 111 values which are only about 10% difference and is completely normal and safe according to this standard. It's not perfect lab accuracy, but it's good enough for daily life with diabetes.
*** I do not promote any companies that make these glucometers.
Research Methodology and Scientific Writing Publisher Springer (2021)
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L'Iran refuse le deux poids, deux mesures occidental qui consiste ร fabriquer les armes les plus sophistiquรฉes tout en privant les autres de moyens de defense.