Raja Ganesan

Architect @AWSCloud. Talks about #containers #k8s #DevX All tweets are personal views and not representing my past or current employer(s)

[Raja Ganesan @zeagord]

Some personal announcement. I am excited to announce that I'm taking on a new role as Cloud Architect at @awscloud. I cannot wait to see where this new chapter of my career will take me, and to grow and learn within this role. #newjob #aws #amazon

[Raja Ganesan @zeagord]

@VancouverSun BC’s economy is already strained (deficits, out-migration pressures, external trade risks). Prioritizing one segment’s framework over broad-based growth and certainty doesn’t serve long-term reconciliation; it risks eroding the tax base and opportunities that lift all boats

[Raja Ganesan @zeagord]

@elonmusk When do we get Tesla SUV?

@grok create a Tesla SUV concept car.

[tobi lutke @tobi]

@JohnNabuurs yep. Canada can be the richest country on planet earth any time it chooses. It's literally just choices.

[TheLiverDoc™ @theliverdoc]

STAY WITH ME.

A few years ago, a patient was referred to me because he was diagnosed with complicated cirrhosis. He had an infection which led to a condition called hepatic encephalopathy (brain failure due to high ammonia levels). The treatment largely involved ammonia reducing therapies. One drug was central to this - Rifaximin - a non-absorbable antibiotic that reduced ammonia in the body. I prescribed him Rifaximin for 6 weeks and advised him follow-up.

He came back to me, not after six weeks, but in 4 weeks, this time, in liver coma (worst stage of brain failure - due to very high ammonia). He spent two days in the ICU and six days in total in the hospital. His hospital bill was close to INR 80,000. He had no insurance and his wife borrowed the money from neighbors and friends to clear hospital dues.

Upon questioning, I found that he was not taking the Rifaximin drug I had prescribed. He was only on the other two drugs (one, a syrup called lactulose for improving ammonia clearance in gut). I was furious, because the patient spent a whole week unecessarily in the ICU and wasted so much money that he never had - just because he was "not compliant" to my orders. I decided it was time for me to school him a bit.

But I was wrong. He was compliant. He had purchased Rifaximin and was on it. For 15 days. Thereafter, he could not afford it. He was an autorickshaw driver who shuttled school children every morning and evening. He could hardly make ends meet. He had two children of his own. The Rifaximin brand I prescribed him was 42 rupees per tablet. He had to consume two a day - which would mean 2520 rupees a month. He just did not have that money - so he skipped it - to not compromise on other important matters - childrens education and food.

He was confused and scared about opting for a cheaper version of Rifaximin because one, he was unsure about the quality of Rifaximin that was not prescribed by me and two, he was "scared" that I would scold him for buying a cheaper Rifaximin and if that got him into trouble.

I was confused and scared about prescribing a cheaper version of Rifaximin because one, I was unsure about the quality of Rifaximin that was not "a good promoted brand" and two, I was "scared" that his family would scold me for prescribing a cheaper Rifaximin and if that got him into trouble.

It is heartbreaking that many doctors still simply don’t trust generic medicines. Too often, they worry that these cheaper options are lower quality or might cause more problems than the big, famous brands. This fear leads them to prescribe expensive drugs instead, and the real tragedy is that it pushes vital healthcare out of reach for the ordinary people who need it most - like my patient.

This narrative, that generic drugs 'are never good' and that only big pharmaceutical marketed drugs are what works has been deeply ingrained into doctors and patients alike - I do not know by whom and since when. Looking back, these strong emotions were based on either opinions, testimonials or second- and third-hand information. Not evidence.

Like I said. Stay with me. This is life changing and will disrupt the drug market in India. Here are the results of The Citizens Generic vs. Brand Drugs Quality Project.
1/11

[HindolSengupta @HindolSengupta]

To celebrate Christmas which falls in between the Marghazi calendar here is the late T. N. Krishnan, Sangeeta Kalanidhi 1980, playing jingle bells at a Music Academy concert, no less, before beginning the Carnatic music.

[Swami Sivasubramanian @SwamiSivasubram]

🚀 Today, we announced frontier agents, a new class of AI agents which are a step-function change in what you can do with agents. Our first three agents mark the beginning of a new era in software development:

🟠 Kiro autonomous agent maintains persistent context and learns over time while working independently, so you can focus on your biggest priorities. It can handle a range of tasks—from triaging bugs to improving code coverage—with a single change spanning multiple repositories.

🟠 AWS Security Agent is your virtual security engineer that helps build secure applications by being a security consultant for app design, code reviews, and penetration testing.

🟠 AWS DevOps Agent is your virtual operations team member that helps resolve and proactively prevent incidents. It is on call when incidents happen, instantly responding to issues and using its knowledge of your application and the relationship between components to find the root ause of the problem.

More on how we’re helping customers driving towards an agentic future: https://t.co/lXre9r73TL

#AWSreInvent

[Swami Sivasubramanian @SwamiSivasubram]

We started the morning here at #AWSreInvent with a keynote from Matt Garman. Great to see the impact AI agents are having on organizations across every industry. @awscloud is building the foundation for billions of agents and pushing past what’s possible with infrastructure and inventing new building blocks for customers. Really excited for how Frontier Agents will transform software development (I’ll break this down in a different post today).

Took some quick notes on the important news from Matt’s talk this morning, here’s my recap:

[Martin Pelletier @MPelletierCIO]

To my American followers. Did you know that the highest marginal tax rate in Ontario and British Columbia is 53.5%, both kicking in at incomes over $253,414. Meanwhile, the minimum income required to buy an average home in Toronto is approximately $225,000, and in Vancouver, it’s even higher at $245,270.

That means the income threshold to afford a home in Canada’s most expensive cities is just shy of the income level taxed at the highest rate. In other words, to simply qualify for a mortgage in these markets, a household must earn an income that is nearly taxed at the top federal-provincial marginal rate. Therefore, by definition, only Canada's very wealthiest can qualify for a mortgage to buy a home.

[Raja Ganesan @zeagord]

@jen_s_nicholson @mkheck Please DM me for any roles that you are interested in Amazon.

[Raja Ganesan @zeagord]

@adityaekbote Wild right.

[Raja Ganesan @zeagord]

Can’t believe the passing of Diogo Jota. Such a great talent and joy to watch. A tragic way to leave too soon. RIP.

[Raja Ganesan @zeagord]

@realEstateTrent Subaru is pretty good. Been using it for a while. Although mine is an older model. 2017 Forester. Starting to give oil issues as it burns fast. Keeping a can of oil to refill all the time. If I ever change, it will be a Toyota RAV4

[Raja Ganesan @zeagord]

Seven year old asked Alexa what is the number before infinity.

Alexa responded beautifully that infinity is not a number and there is no specific number before infinity in a way he can understand.

Impressed by both.

[Raja Ganesan @zeagord]

@gwenshap AWS SAM or CDK. Mostly CDK for production. Used SST as well which works great with CDK.

[Raja Ganesan @zeagord]

@golub U yo I