@jeromeleonard5 Oh, I forgot about PRMT5/MAT2A
Point still the same, even if not all of them hit, ultimately the share price doesnβt count the Daro opportunity, not even close. And the closer is Daro to approval, the firmer is the floor on valuation
@jeromeleonard5 Probably first data from B7-H3 PTK7
and maybe some data from dose escalation of their KAT6/7, though its probably pushing to the end of Q1
@jeromeleonard5 am I wrong though? Around YE or slightly afterwards we should have Daro approved (with a few options that are not priced in like wide label, or full approval on OS trend)
Updates on DLL3 ADC, initial data for DLL3 ADC + PARG - where PARG could be best in class, first in class
IMO the question is not about carcinogenicity, as those tumors probably existed before those people started to take obe. Just the rate of multiplication doesnβt allow for cancer to grow from 1 cell to a detectable blob in 1 year. Its more about immune system not killing those cancers
@DmitryKovalchuk signals immune system to chill out >> decreased cancer surveillance >> more cancers 'mature'
it suddenly become a 'too hard' story for a lot of people
Sorry for an unrelated question but I would love to know your opinion on concerns that COR1M is at peak low right now and should mean revert bringing some carnage along the way. Do you think that the IV differential could be a factor for reversal on itself? Or is just a downstream thing and the fact that it usually mean reverts stems from state of the market itself and simply because it cant go much lower mathematically
I assume those are not fix rate loans though and SOFR can rise dramatically
Maybe it actually favours the dry bulk market the most as those are cheaper ships and with demand for tankers high, its probably harder to get a slot for a dry bulk newbuild. Fleet is already aged and it may push the renewal even further