@MidwesternDoc@Terpolska1 Can you use a typical topical DMSO gel or cream on the gums directly or just nearby on the skin outside the mouth near the tooth that is affected?
In 15+ years of Obesity Medicine practice I had same or better results with low carb diets or meal replacement diets with or WITHOUT older medications such as phentermine, Qsymia, Contrave including the lipid benefits you described. On a low carb diet, triglycerides in particular drop greatly and quickly and fatty liver resolves. That doesn’t mean retatrutide isn’t beneficial; just that these results are achievable by other means as well. So if someone doesn’t tolerate or want the new meds, there are other modalities that achieve the same or better results. Footnote: Sema, Tirz, and Reta all pair nicely mechanistically with low carb/real food diets to enhance and maintain the benefits.
Nicolas. This is interesting personally. I had life threatening side effects to the Pfizer vaccine (among the diagnoses you have in all caps above) in February/March 2021. I filed a VAERS report and the only thing I got back in response was a request for the lot number of the vaccine I received (which was ALREADY in the report I had filed🤦🏻). There was no request for medical records from me (a physician) or any of my physicians. It was as if they just didn’t want to know…🤔
@P_McCulloughMD For anyone reading this post. Please note that after doing this procedure they GRADUALLY reintroduced meat. Mostly participants who had success did not consist back to consuming the quantity of meat they were eating before alpha gal syndrome presented.
Long post warning: Kyle, assuming you have obstructive sleep apnea and not central sleep apnea. Think of this as due to obstruction of the upper airway. This can be due to many things. Though it simply could be obstruction by enlarged tonsils/adenoids I have to assume this has been ruled out already. In the larger percentage of people OSA is correlated with a large neck circumference—17 or more inches in men. In a typical patient this enlarged neck circumference is due to excess fat. Thus the classic recommendation to lose “weight.” In your case, you likely have a normal or low fat percentage as an athlete; so it may be your genetic ability to hypertrophy muscles (in your neck in particular) to a large degree and the high percentage neck muscle mass you’ve likely built up since your teen years when you likely started lifting heavy and training for football. Excess muscle mass can cause enlarged neck circumference and airway obstruction just like excess fat could. Now clearly you need those strong neck muscles to prevent serious injury with football impacts, so changing that is tricky and probably not advised while you’re still playing. That being said, patients with normal weight/fat percentage may benefit from a ketogenic diet for improving sleep apnea. The benefits of this diet for sleep apnea are not just weight/fat loss which you likely don’t need. It can decrease inflammation that may be present, and decrease fluid retention just enough to relieve the airway obstruction leading to sleep apnea. It also may improve acid reflux which you stated you had and can also contribute to sleep apnea. If you tried this type of diet you need professional supervision to make sure you can perform athletically and not lose muscle mass that you need. Others have suggested a dental appliance which also may help. This is VERY dependent on the practitioner and manufacturer as to how effective and comfortable the device is. There is some trial and error involved in finding the right practitioner for this. I hope this is helpful.
@ChrisMasterjohn Great analysis. The other thing I took away from it was something I’ve always wondered about that Korean War Military study so often cited. Did “approximately” 77% of US Korean War soldiers in 1953 smoke…. 🤔
Doctors by and large aren’t recognizing this very real increase. An internist might diagnose only 1-5 new cases of cancer of any type in an entire month. So increases of these cancers in this range are largely imperceptible to any one doctor in their course of practice. Oncologists also typically are fully booked and may not have a feel for the increase in referrals to their practice and the time increases for new patients to get an appointment with them due to these cancer rate increases. What may be more noticeable is for instance rarer cancers I or colleagues have seen (appendiceal, cholangiocarcinoma for example) and more common cancers occurring in patients at a MUCH earlier age or at later stages than typical before the vaccine roll out.
Occupationally, you are of course at risk for osteoarthritis…in multiple joints. So, seeing a specialist (Rheumatologist or orthopedist) for a good history and exam and workup is a good idea. That being said and without knowing your complete history or examining you to guide treatment, I couldn’t give actual medical advice; but here are some general thoughts if I were seeing a patient with bilateral knee inflammation/pain. I would first want to rule out certain treatable causes of inflammatory arthritis. Initial bloodwork might be a CBC, ESR, ANA, Rheumatoid, factor and lyme antibody test…maybe a uric acid level as well. +/- x rays as well. If those were all essentially negative, and routine antiinflammatories didn’t help, and you wanted to try some alternative treatments, there are several things patients have tried that may have some benefit. Some patients have found benefit from a ketogenic diet or at least a very low carb, real food diet (just proteins and non-starchy vegetables). As you are lean, you would need to be careful to eat enough calories to not lose weight on this type of diet. This eating pattern decreases inflammation systemically, thus its benefit. Low level laser therapy (photobiomodulation) has helped many patients decrease orthopedic pain and inflammation. This requires multiple treatments over time but can be “magical” in its benefit in certain patients. There is a practice “Ortho Lazer” with multiple sites around the country that specializes in this. Some patients have used topical DMSO/aloe gel (yes its available on amazon) with success. This compound is a little controversial and should only be used under the supervision of a knowledgeable practitioner. There are treatments I am less knowledgeable about like certain peptides that are purported to have benefit in decreasing pain and inflammation..and there are practitioners who specialize in this; though the hard part is finding someone reputable in that field. If it turns out to be wear and tear from years of football, and you want to try something non-surgical, PRP and/or stem cell treatments have been used but the benefit may depend greatly on the exact diagnosis AND experience of the practitioner. There are also other conventional modalities and therapies that you as an athlete likely have access to. I hope this helps and good luck!
Childhood vaccines: no known issues except maybe a rash to a measles vaccine. (Unclear if related in retrospect: Severe allergies and eczema through youth into teens.)
DT: no issues
DTP: Month of sore arm, and diffuse myalgias.
Pneumovax (x2): no issues
Annual flu vaccine: sometimes no issues, sometimes sore arm and days to week of fatigue/aches.
Varicella vaccine (as young adult. Never had chicken pox as child): Severe rash that mimicked chicken pox. Got chicken pox a few years later anyway.
Hepatitis B series: no issues
Covid vaccine 1: sudden tachycardia. Diffuse ice pick neuropathy.
Covid vaccine 2: Fever, repeat of diffuse ice pick neuropathy, possible pericarditis, pleuritis and costochondritis followed by life threatening coronary artery blood clots, atrial and ventricular arrythmias, persistent and relapsing dysautonomia, relapsing musculoskeletal inflammation, relapsing genitourinary inflammation, weight gain, dysbiosis and gastroparesis, forced retirement/loss of career.
Neil, Dexamethasone wasn’t found to be “effective for COVID” In the way you are suggesting. The landmark NEJM study showed benefits in hospitalized patient treatment not early outpatient treatment so it would have had no effect on a vaccine EUA. In fact one study at least showed worse outcomes with EARLY dexamethasone treatment. My understanding of Kennedy and Rogans view is if a cheap repurposed drug like IV M and hydroxy was available that showed benefit particularly in early outpt treatment of Covid, then EUA could not have been granted. And they are correct in that such data did exist, clinical experience data also existed and it all was largely suppressed. In reality, both vax and ALL early treatment pathways should have been pursued concurrently in an ideal world. But as you know it became a political issue not just a medical issue…